Generation of inner ear hair cells by direct lineage conversion of primary somatic cells L Menendez, T Trecek, S Gopalakrishnan, L Tao, AL Markowitz, HV Yu, ... elife 9, e55249, 2020 | 75 | 2020 |
Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1 HI Jen, MC Hill, L Tao, K Sheng, W Cao, H Zhang, HV Yu, J Llamas, ... Elife 8, e44328, 2019 | 61 | 2019 |
POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism HV Yu, L Tao, J Llamas, X Wang, JD Nguyen, T Trecek, N Segil Proceedings of the National Academy of Sciences 118 (29), e2105137118, 2021 | 57 | 2021 |
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration L Tao, VY Haoze, J Llamas, T Trecek, X Wang, Z Stojanova, AK Groves, ... Developmental cell 56 (17), 2471-2485. e5, 2021 | 49 | 2021 |
Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal K Gnedeva, X Wang, MM McGovern, M Barton, L Tao, T Trecek, ... Proceedings of the National Academy of Sciences 117 (24), 13552-13561, 2020 | 43 | 2020 |
Early transcriptional response to aminoglycoside antibiotic suggests alternate pathways leading to apoptosis in sensory hair cells in the mouse inner ear L Tao, N Segil Frontiers in cellular neuroscience 9, 190, 2015 | 41 | 2015 |
Tri‐layered and gel‐like nanofibrous scaffolds with anisotropic features for engineering heart valve leaflets S Wu, Y Li, C Zhang, L Tao, M Kuss, JY Lim, J Butcher, B Duan Advanced healthcare materials 11 (10), 2200053, 2022 | 35 | 2022 |
Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea P Salehi, MX Ge, U Gundimeda, L Michelle Baum, H Lael Cantu, ... PLoS Genetics 13 (10), e1007048, 2017 | 27 | 2017 |
STAT3 promotes a youthful epigenetic state in articular chondrocytes A Sarkar, NQ Liu, J Magallanes, J Tassey, S Lee, R Shkhyan, Y Lee, J Lu, ... Aging Cell 22 (2), e13773, 2023 | 21 | 2023 |
GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor HI Jen, S Singh, L Tao, HR Maunsell, N Segil, AK Groves Scientific Reports 12 (1), 7793, 2022 | 18 | 2022 |
Endoplasmic Reticulum Mediated Necrosis-like Apoptosis of Hela Cells Induced by Ca^ 2^+ Oscillation Q Hu, J Chang, L Tao, G Yan, M Xie, Z Wang Journal of Biochemistry and Molecular Biology 38 (6), 709, 2005 | 16 | 2005 |
Characterization of the expression of CTRP9, a paralog of adiponectin Z Huang, T Cui, J Liu, Y Zhuang, Q Meng, L Tao, Z Li Tsinghua Science & Technology 13 (4), 492-499, 2008 | 15 | 2008 |
SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti X Wang, J Llamas, T Trecek, T Shi, L Tao, W Makmura, JG Crump, N Segil, ... Proceedings of the National Academy of Sciences 120 (34), e2301301120, 2023 | 7 | 2023 |
The role of molecular and cellular aging pathways on age-related hearing loss T Ege, L Tao, BJ North International journal of molecular sciences 25 (17), 9705, 2024 | 4 | 2024 |
CDK2 regulates aminoglycoside-induced hair cell death through modulating c-Jun activity: Inhibiting CDK2 to preserve hearing L Tao, N Segil Frontiers in Molecular Neuroscience 15, 1013383, 2022 | 3 | 2022 |
Investigation of the molecular mechanisms of ototoxicity L Tao University of Southern California, 2014 | 1 | 2014 |
Rational design of a Lfng-enhancer AAV construct drives specific and efficient gene expression in inner ear supporting cells R Seist, JS Copeland, L Tao, AK Groves Hearing Research, 109203, 2025 | | 2025 |
Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells RN Rainey, SD Houman, L Menendez, R Chang, L Tao, H Bugacov, ... bioRxiv, 2025.02. 20.639352, 2025 | | 2025 |
Single-cell Transcriptomics Unravel Stereocilia Degeneration as a Key Contributor to Age-related Vestibular Dysfunction in Mice and Humans S Kulasooriya, H Liu, S Vijayakumar, C Bloom, S Tu, B Borgmeier, ... bioRxiv, 2025.02. 02.636113, 2025 | | 2025 |
Genome-wide DNA methylation and multi-omics study of human chondrocyte ontogeny and an epigenetic clock analysis of adult chondrocytes A Sarkar, S Lee, R Shkhyan, NQ Liu, BV Handel, J Magallanes, Y Lee, ... bioRxiv, 2021.08. 02.454544, 2021 | | 2021 |