| Application of BRET to monitor ligand binding to GPCRs LA Stoddart, EKM Johnstone, AJ Wheal, J Goulding, MB Robers, ... Nature methods 12 (7), 661-663, 2015 | 285 | 2015 |
| NanoBRET: the bright future of proximity-based assays NC Dale, EKM Johnstone, CW White, KDG Pfleger Frontiers in Bioengineering and Biotechnology 7, 56, 2019 | 186 | 2019 |
| Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer C Duffy, A Sorolla, E Wang, E Golden, E Woodward, K Davern, D Ho, ... NPJ precision oncology 4 (1), 24, 2020 | 137 | 2020 |
| Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis RJ Pickering, C Tikellis, CJ Rosado, D Tsorotes, A Dimitropoulos, M Smith, ... The Journal of clinical investigation 129 (1), 406-421, 2019 | 81 | 2019 |
| Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time CW White, HK Vanyai, HB See, EKM Johnstone, KDG Pfleger Scientific Reports 7 (1), 3187, 2017 | 61 | 2017 |
| Functional interaction between angiotensin II receptor type 1 and chemokine (CC motif) receptor 2 with implications for chronic kidney disease MA Ayoub, Y Zhang, RS Kelly, HB See, EKM Johnstone, EA McCall, ... PLoS One 10 (3), e0119803, 2015 | 56 | 2015 |
| AT1R-AT2R-RXFP1 functional crosstalk in myofibroblasts: impact on the therapeutic targeting of renal and cardiac fibrosis BSM Chow, M Kocan, M Shen, Y Wang, L Han, JY Chew, C Wang, ... Journal of the American Society of Nephrology 30 (11), 2191-2207, 2019 | 44 | 2019 |
| NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing CW White, EKM Johnstone, HB See, KDG Pfleger Cellular signalling 54, 27-34, 2019 | 39 | 2019 |
| Orexin signaling: a complex, multifaceted process NC Dale, D Hoyer, LH Jacobson, KDG Pfleger, EKM Johnstone Frontiers in Cellular Neuroscience 16, 812359, 2022 | 33 | 2022 |
| The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer E Golden, R Rashwan, EA Woodward, A Sgro, E Wang, A Sorolla, ... Nature Communications 12 (1), 1920, 2021 | 32 | 2021 |
| GPCR heteromers: an overview of their classification, function and physiological relevance NC Dale, EKM Johnstone, KDG Pfleger Frontiers in Endocrinology 13, 931573, 2022 | 31 | 2022 |
| BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes SL O'Brien, EKM Johnstone, D Devost, J Conroy, ME Reichelt, ... Biochemical pharmacology 158, 232-242, 2018 | 25 | 2018 |
| Receptor-Heteromer Investigation Technology and its application using BRET EKM Johnstone, KDG Pfleger Frontiers in endocrinology 3, 101, 2012 | 23 | 2012 |
| Investigation of receptor heteromers using NanoBRET ligand binding EKM Johnstone, HB See, RS Abhayawardana, A Song, KJ Rosengren, ... International journal of molecular sciences 22 (3), 1082, 2021 | 16 | 2021 |
| Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer. NPJ Precis Oncol 4: 24 C Duffy, A Sorolla, E Wang, E Golden, E Woodward, K Davern, D Ho, ... | 14 | 2020 |
| Insights into the interaction of LVV-Hemorphin-7 with angiotensin II type 1 receptor A Ali, EKM Johnstone, B Baby, HB See, A Song, KJ Rosengren, ... International journal of molecular sciences 22 (1), 209, 2020 | 7 | 2020 |
| Novel pharmacology following heteromerization of the angiotensin II type 2 receptor and the bradykinin type 2 receptor EKM Johnstone, MA Ayoub, RJ Hertzman, HB See, RS Abhayawardana, ... Frontiers in Endocrinology 13, 848816, 2022 | 5 | 2022 |
| Bioluminescence resonance energy transfer approaches to discover bias in GPCR signaling EKM Johnstone, KDG Pfleger G Protein-Coupled Receptors in Drug Discovery: Methods and Protocols, 191-204, 2015 | 5 | 2015 |
| Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners EKM Johnstone, RS Abhayawardana, HB See, RM Seeber, SL O'Brien, ... Biochemical Pharmacology 188, 114521, 2021 | 4 | 2021 |
| Bioluminescence resonance energy transfer (BRET) technologies to study GPCRs NC Dale, CW White, EKM Johnstone, KDG Pfleger GPCRs as Therapeutic Targets 2, 841-873, 2022 | 3 | 2022 |
Professor Kevin PflegerThe University of Western Australia and Harry Perkins Institute of Medical ResearchEmail được xác minh tại uwa.edu.au
