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| An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium Nature 489 (7414), 57-74, 2012 | 17594 | 2012 |
| Massively parallel digital transcriptional profiling of single cells GXY Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ... Nature Communications 8, 14049, 2017 | 6438 | 2017 |
| Integrative analysis of 111 reference human epigenomes EC Roadmap, A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, ... Nature 518, 317-330, 2015 | 6418* | 2015 |
| A bivalent chromatin structure marks key developmental genes in embryonic stem cells BE Bernstein, TS Mikkelsen, X Xie, M Kamal, DJ Huebert, J Cuff, B Fry, ... Cell 125 (2), 315-326, 2006 | 6408 | 2006 |
| The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells C Trapnell, D Cacchiarelli, J Grimsby, P Pokharel, S Li, M Morse, ... Nature biotechnology 32 (4), 381-386, 2014 | 5997 | 2014 |
| Genome-scale CRISPR-Cas9 knockout screening in human cells O Shalem, NE Sanjana, E Hartenian, X Shi, DA Scott, TS Mikkelsen, ... Science 343 (6166), 84-87, 2014 | 5915 | 2014 |
| Genome-wide maps of chromatin state in pluripotent and lineage-committed cells TS Mikkelsen, M Ku, DB Jaffe, B Issac, E Lieberman, G Giannoukos, ... Nature 448 (7153), 553-560, 2007 | 5005 | 2007 |
| Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ... Nature 458 (7235), 223-227, 2009 | 4914 | 2009 |
| Mapping and analysis of chromatin state dynamics in nine human cell types J Ernst, P Kheradpour, TS Mikkelsen, N Shoresh, LD Ward, CB Epstein, ... Nature 473 (7345), 43-49, 2011 | 3381 | 2011 |
| Genome sequence, comparative analysis and haplotype structure of the domestic dog K Lindblad-Toh, CM Wade, TS Mikkelsen, EK Karlsson, DB Jaffe, ... Nature 438 (7069), 803-819, 2005 | 3194 | 2005 |
| Genome-scale DNA methylation maps of pluripotent and differentiated cells A Meissner, TS Mikkelsen, H Gu, M Wernig, J Hanna, A Sivachenko, ... Nature 454 (7205), 766-770, 2008 | 3053 | 2008 |
| The ENCODE (ENCyclopedia of DNA elements) project ENCODE Project Consortium Science 306 (5696), 636-640, 2004 | 2460* | 2004 |
| Initial sequence of the chimpanzee genome and comparison with the human genome TC Sequencing, Analysis Consortium Nature 437 (7055), 69-87, 2005 | 2321 | 2005 |
| The NIH roadmap epigenomics mapping consortium BE Bernstein, JA Stamatoyannopoulos, JF Costello, B Ren, ... Nature biotechnology 28 (10), 1045-1048, 2010 | 1976 | 2010 |
| Dissecting direct reprogramming through integrative genomic analysis TS Mikkelsen, J Hanna, X Zhang, M Ku, M Wernig, P Schorderet, ... Nature 454 (7200), 49-55, 2008 | 1861 | 2008 |
| A user's guide to the encyclopedia of DNA elements (ENCODE) ENCODE Project Consortium PLoS biology 9 (4), e1001046, 2011 | 1499 | 2011 |
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| Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains M Ku, RP Koche, E Rheinbay, EM Mendenhall, M Endoh, TS Mikkelsen, ... PLoS genetics 4 (10), e1000242, 2008 | 1190 | 2008 |
Bradley BernsteinProfessor of Pathology, Harvard UniversityEmail được xác minh tại broadinstitute.org