Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCζ-dependent mechanism DJ Powell, E Hajduch, G Kular, HS Hundal Molecular and cellular biology 23 (21), 7794-7808, 2003 | 464 | 2003 |
Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes M Daval, F Diot-Dupuy, R Bazin, I Hainault, B Viollet, S Vaulont, ... Journal of Biological Chemistry 280 (26), 25250-25257, 2005 | 434 | 2005 |
Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen … E Hajduch, DR Alessi, BA Hemmings, HS Hundal Diabetes 47 (7), 1006-1013, 1998 | 432 | 1998 |
Protein kinase B (PKB/Akt)–a key regulator of glucose transport? E Hajduch, GJ Litherland, HS Hundal FEBS letters 492 (3), 199-203, 2001 | 397 | 2001 |
New insights into ER stress-induced insulin resistance M Flamment, E Hajduch, P Ferré, F Foufelle Trends in Endocrinology & Metabolism 23 (8), 381-390, 2012 | 382 | 2012 |
Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells DJ Powell, S Turban, A Gray, E Hajduch, HS Hundal Biochemical Journal 382 (2), 619-629, 2004 | 337 | 2004 |
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells E Hajduch, A Balendran, IH Batty, GJ Litherland, AS Blair, CP Downes, ... Diabetologia 44, 173-183, 2001 | 299 | 2001 |
L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the … K PEYROLLIER, E HAJDUCH, AS BLAIR, R HYDE, HS HUNDAL Biochemical Journal 350 (2), 361-368, 2000 | 246 | 2000 |
Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase. LG Fryer, E Hajduch, F Rencurel, IP Salt, HS Hundal, DG Hardie, ... Diabetes 49 (12), 1978-1985, 2000 | 241 | 2000 |
Cholesterol‐induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis S Le Lay, E Hajduch, MR Lindsay, X Le Lièpvre, C Thiele, P Ferré, ... Traffic 7 (5), 549-561, 2006 | 221 | 2006 |
IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde? S Perrier, F Darakhshan, E Hajduch FEBS letters 580 (27), 6289-6294, 2006 | 215 | 2006 |
Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress: evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated … AS Blair, E Hajduch, GJ Litherland, HS Hundal Journal of Biological Chemistry 274 (51), 36293-36299, 1999 | 205 | 1999 |
Serotonin (5-hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle E Hajduch, F Rencurel, A Balendran, IH Batty, CP Downes, HS Hundal Journal of Biological Chemistry 274 (19), 13563-13568, 1999 | 163 | 1999 |
Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance S Turban, E Hajduch FEBS letters 585 (2), 269-274, 2011 | 157 | 2011 |
Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells R Hyde, E Hajduch, DJ Powell, PM Taylor, HS Hundal The FASEB journal 19 (3), 1-24, 2005 | 157 | 2005 |
Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner GR Christie, E Hajduch, HS Hundal, CG Proud, PM Taylor Journal of Biological Chemistry 277 (12), 9952-9957, 2002 | 147 | 2002 |
Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide E Hajduch, S Turban, X Le Liepvre, S Le Lay, C Lipina, N Dimopoulos, ... Biochemical Journal 410 (2), 369-379, 2008 | 145 | 2008 |
Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling CM Blouin, C Prado, KK Takane, F Lasnier, A Garcia-Ocana, P Ferré, ... Diabetes 59 (3), 600-610, 2010 | 144 | 2010 |
Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects CM Blouin, S Le Lay, A Eberl, HC Köfeler, IC Guerrera, C Klein, ... Journal of lipid research 51 (5), 945-956, 2010 | 135 | 2010 |
Fish oil in a high lard diet prevents obesity, hyperlipemia, and adipocyte insulin resistance in rats. I Hainault, M Carlotti, E Hajduch, C Guichard, M Lavau | 133 | 1993 |