mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt KE O'Reilly, F Rojo, QB She, D Solit, GB Mills, D Smith, H Lane, ... Cancer research 66 (3), 1500-1508, 2006 | 3033 | 2006 |
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity LH Saal, P Johansson, K Holm, SK Gruvberger-Saal, QB She, M Maurer, ... Proceedings of the National Academy of Sciences 104 (18), 7564-7569, 2007 | 647 | 2007 |
Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase QB She, AM Bode, WY Ma, NY Chen, Z Dong Cancer research 61 (4), 1604-1610, 2001 | 548 | 2001 |
The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells QB She, DB Solit, Q Ye, KE O’Reilly, J Lobo, N Rosen Cancer cell 8 (4), 287-297, 2005 | 485 | 2005 |
4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors QB She, E Halilovic, Q Ye, W Zhen, S Shirasawa, T Sasazuki, DB Solit, ... Cancer cell 18 (1), 39-51, 2010 | 457 | 2010 |
ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation QB She, N Chen, Z Dong Journal of Biological Chemistry 275 (27), 20444-20449, 2000 | 442 | 2000 |
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling QB She, S Chandarlapaty, Q Ye, J Lobo, KM Haskell, KR Leander, ... PloS one 3 (8), e3065, 2008 | 364 | 2008 |
Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive … QB She, D Solit, A Basso, MM Moasser Clinical Cancer Research 9 (12), 4340-4346, 2003 | 354 | 2003 |
Suppression of skin tumorigenesis in c-Jun NH2-terminal kinase-2-deficient mice N Chen, M Nomura, QB She, WY Ma, AM Bode, L Wang, RA Flavell, ... Cancer research 61 (10), 3908-3912, 2001 | 282 | 2001 |
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF F Xing, Y Persaud, CA Pratilas, BS Taylor, M Janakiraman, QB She, ... Oncogene 31 (4), 446-457, 2012 | 249 | 2012 |
Deficiency of c-Jun-NH2-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate QB She, N Chen, AM Bode, RA Flavell, Z Dong Cancer research 62 (5), 1343-1348, 2002 | 221 | 2002 |
Models from experiments: combinatorial drug perturbations of cancer cells S Nelander, W Wang, B Nilsson, QB She, C Pratilas, N Rosen, ... Molecular systems biology 4 (1), 216, 2008 | 216 | 2008 |
A novel lectin with potent immunomodulatory activity isolated from both fruiting bodies and cultured mycelia of the edible MushroomVolvariella volvacea QB She, TB Ng, WK Liu Biochemical and Biophysical Research Communications 247 (1), 106-111, 1998 | 209 | 1998 |
PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling E Halilovic, QB She, Q Ye, R Pagliarini, WR Sellers, DB Solit, N Rosen Cancer research 70 (17), 6804-6814, 2010 | 194 | 2010 |
ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer Q Ye, W Cai, Y Zheng, BM Evers, QB She Oncogene 33 (14), 1828-1839, 2014 | 184 | 2014 |
A simple HPLC method for the determination of S-adenosylmethionine and S-adenosylhomocysteine in rat tissues: the effect of vitamin B6 deficiency on these concentrations in rat … QB She, I Nagao, T Hayakawa, H Tsuge Biochemical and Biophysical Research Communications 205 (3), 1748-1754, 1994 | 139 | 1994 |
Involvement of c‐jun NH2‐terminal kinases in resveratrol‐induced activation of p53 and apoptosis QB She, C Huang, Y Zhang, Z Dong Molecular Carcinogenesis: Published in cooperation with the University of …, 2002 | 134 | 2002 |
Genomic complexity and AKT dependence in serous ovarian cancer AJ Hanrahan, N Schultz, ML Westfal, RA Sakr, DD Giri, S Scarperi, ... Cancer discovery 2 (1), 56-67, 2012 | 129 | 2012 |
Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation QB She, WY Ma, S Zhong, Z Dong Journal of Biological Chemistry 277 (27), 24039-24048, 2002 | 124 | 2002 |
AKT and cancer—is it all mTOR? N Rosen, QB She Cancer cell 10 (4), 254-256, 2006 | 97 | 2006 |