Theo dõi
Justin Gainor
Justin Gainor
Director, Center for Thoracic Cancers Program, Massachusetts General Hospital
Email được xác minh tại partners.org
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Nivolumab versus docetaxel in advanced squamous-cell non–small-cell lung cancer
J Brahmer, KL Reckamp, P Baas, L Crinò, WEE Eberhardt, ...
New England Journal of Medicine 373 (2), 123-135, 2015
92932015
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
NM Kuderer, TK Choueiri, DP Shah, Y Shyr, SM Rubinstein, DR Rivera, ...
The Lancet 395 (10241), 1907-1918, 2020
19632020
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ...
Cancer discovery 8 (7), 822-835, 2018
14102018
Molecular determinants of response to anti–programmed cell death (PD)-1 and anti–programmed death-ligand 1 (PD-L1) blockade in patients with non–small-cell lung cancer profiled …
H Rizvi, F Sanchez-Vega, K La, W Chatila, P Jonsson, D Halpenny, ...
Journal of clinical oncology 36 (7), 633-641, 2018
13402018
EGFR mutations and ALK rearrangements are associated with low response rates to PD-1 pathway blockade in non–small cell lung cancer: a retrospective analysis
JF Gainor, AT Shaw, LV Sequist, X Fu, CG Azzoli, Z Piotrowska, ...
Clinical cancer research 22 (18), 4585-4593, 2016
12192016
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer
JF Gainor, L Dardaei, S Yoda, L Friboulet, I Leshchiner, R Katayama, ...
Cancer discovery 6 (10), 1118-1133, 2016
11912016
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis
AT Shaw, BY Yeap, BJ Solomon, GJ Riely, J Gainor, JA Engelman, ...
The lancet oncology 12 (11), 1004-1012, 2011
11542011
The ALK inhibitor ceritinib overcomes crizotinib resistance in non–small cell lung cancer
L Friboulet, N Li, R Katayama, CC Lee, JF Gainor, AS Crystal, ...
Cancer discovery 4 (6), 662-673, 2014
9432014
Patient-derived models of acquired resistance can identify effective drug combinations for cancer
AS Crystal, AT Shaw, LV Sequist, L Friboulet, MJ Niederst, EL Lockerman, ...
Science 346 (6216), 1480-1486, 2014
8142014
Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell Lung Cancer
A Drilon, GR Oxnard, DSW Tan, HHF Loong, M Johnson, J Gainor, ...
New England Journal of Medicine 383 (9), 813-824, 2020
8012020
Lorlatinib in non-small-cell lung cancer with ALK or ROS1 rearrangement: an international, multicentre, open-label, single-arm first-in-man phase 1 trial
AT Shaw, E Felip, TM Bauer, B Besse, A Navarro, S Postel-Vinay, ...
The Lancet Oncology 18 (12), 1590-1599, 2017
7212017
ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer
JF Gainor, AM Varghese, SHI Ou, S Kabraji, MM Awad, R Katayama, ...
Clinical cancer research 19 (15), 4273-4281, 2013
6782013
First-line nivolumab plus ipilimumab in advanced non–small-cell lung cancer (CheckMate 568): outcomes by programmed death ligand 1 and tumor mutational burden as biomarkers
N Ready, MD Hellmann, MM Awad, GA Otterson, M Gutierrez, JF Gainor, ...
Journal of Clinical Oncology 37 (12), 992-1000, 2019
5792019
Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial
CA Shu, JF Gainor, MM Awad, C Chiuzan, CM Grigg, A Pabani, ...
The Lancet Oncology 21 (6), 786-795, 2020
5642020
Resensitization to crizotinib by the lorlatinib ALK resistance mutation L1198F
AT Shaw, L Friboulet, I Leshchiner, JF Gainor, S Bergqvist, A Brooun, ...
New England Journal of Medicine 374 (1), 54-61, 2016
5502016
PF-06463922, an ALK/ROS1 inhibitor, overcomes resistance to first and second generation ALK inhibitors in preclinical models
HY Zou, L Friboulet, DP Kodack, LD Engstrom, Q Li, M West, RW Tang, ...
Cancer cell 28 (1), 70-81, 2015
5052015
Nivolumab versus docetaxel in previously treated advanced non-small-cell lung cancer (CheckMate 017 and CheckMate 057): 3-year update and outcomes in patients with liver metastases
EE Vokes, N Ready, E Felip, L Horn, MA Burgio, SJ Antonia, OA Frontera, ...
Annals of oncology 29 (4), 959-965, 2018
4962018
Acquired resistance to crizotinib from a mutation in CD74–ROS1
MM Awad, R Katayama, M McTigue, W Liu, YL Deng, A Brooun, ...
New England Journal of Medicine 368 (25), 2395-2401, 2013
4782013
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
LV Sequist, RS Heist, AT Shaw, P Fidias, R Rosovsky, JS Temel, ...
Annals of oncology 22 (12), 2616-2624, 2011
4762011
A combinatorial strategy for treating KRAS-mutant lung cancer
E Manchado, S Weissmueller, JP Morris, CC Chen, R Wullenkord, ...
Nature 534 (7609), 647-651, 2016
4372016
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