Acidity generated by the tumor microenvironment drives local invasion V Estrella, T Chen, M Lloyd, J Wojtkowiak, HH Cornnell, ... Cancer research 73 (5), 1524-1535, 2013 | 1462 | 2013 |
Bicarbonate increases tumor pH and inhibits spontaneous metastases IF Robey, BK Baggett, ND Kirkpatrick, DJ Roe, J Dosescu, BF Sloane, ... Cancer research 69 (6), 2260-2268, 2009 | 793 | 2009 |
Neutralization of tumor acidity improves antitumor responses to immunotherapy S Pilon-Thomas, KN Kodumudi, AE El-Kenawi, S Russell, AM Weber, ... Cancer research 76 (6), 1381-1390, 2016 | 605 | 2016 |
Imaging pH and metastasis AI Hashim, X Zhang, JW Wojtkowiak, GV Martinez, RJ Gillies NMR in Biomedicine 24 (6), 582-591, 2011 | 309 | 2011 |
Acid suspends the circadian clock in hypoxia through inhibition of mTOR ZE Walton, CH Patel, RC Brooks, Y Yu, A Ibrahim-Hashim, M Riddle, ... Cell 174 (1), 72-87. e32, 2018 | 225 | 2018 |
Hypoxia and acidosis: immune suppressors and therapeutic targets S Damgaci, A Ibrahim‐Hashim, PM Enriquez‐Navas, S Pilon‐Thomas, ... Immunology 154 (3), 354-362, 2018 | 203 | 2018 |
Immunohistochemistry in the evaluation of neovascularization in tumor xenografts D Wang, CR Stockard, L Harkins, P Lott, C Salih, K Yuan, D Buchsbaum, ... Biotechnic & histochemistry 83 (3-4), 179-189, 2008 | 199 | 2008 |
Targeting the metabolic microenvironment of tumors KM Bailey, JW Wojtkowiak, AI Hashim, RJ Gillies Advances in pharmacology 65, 63-107, 2012 | 183 | 2012 |
A physical sciences network characterization of non-tumorigenic and metastatic cells Scientific reports 3 (1), 1449, 2013 | 178 | 2013 |
Acidosis and cancer: from mechanism to neutralization A Ibrahim-Hashim, V Estrella Cancer and Metastasis Reviews 38, 149-155, 2019 | 147 | 2019 |
Cancer‐associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF‐κB activation S Avnet, G Di Pompo, T Chano, C Errani, A Ibrahim‐Hashim, RJ Gillies, ... International journal of cancer 140 (6), 1331-1345, 2017 | 143 | 2017 |
Systemic buffers inhibit carcinogenesis in TRAMP mice A Ibrahim-Hashim, HH Cornnell, D Abrahams, M Lloyd, M Bui, RJ Gillies, ... The Journal of urology 188 (2), 624-631, 2012 | 139 | 2012 |
Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer A El-Kenawi, C Gatenbee, M Robertson-Tessi, R Bravo, J Dhillon, ... British journal of cancer 121 (7), 556-566, 2019 | 137 | 2019 |
T-cells produce acidic niches in lymph nodes to suppress their own effector functions H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, ... Nature communications 11 (1), 4113, 2020 | 133 | 2020 |
Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution A Ibrahim-Hashim, M Robertson-Tessi, PM Enriquez-Navas, M Damaghi, ... Cancer research 77 (9), 2242-2254, 2017 | 133 | 2017 |
Reduction of metastasis using a non-volatile buffer A Ibrahim Hashim, HH Cornnell, ML Coelho Ribeiro, D Abrahams, ... Clinical & experimental metastasis 28, 841-849, 2011 | 116 | 2011 |
Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance D Verduzco, M Lloyd, L Xu, A Ibrahim-Hashim, Y Balagurunathan, ... PloS one 10 (3), e0120958, 2015 | 100 | 2015 |
Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function G Szebenyi, B Hall, R Yu, AI Hashim, H Krämer Traffic 8 (1), 32-46, 2007 | 73 | 2007 |
Free base lysine increases survival and reduces metastasis in prostate cancer model A Ibrahim-Hashim, JW Wojtkowiak, MLC Ribeiro, V Estrella, KM Bailey, ... Journal of cancer science & therapy, JCST-S1-004, 2011 | 67 | 2011 |
Tris–base buffer: a promising new inhibitor for cancer progression and metastasis A Ibrahim‐Hashim, D Abrahams, PM Enriquez‐Navas, K Luddy, ... Cancer medicine 6 (7), 1720-1729, 2017 | 62 | 2017 |