| Generation of knock-in primary human T cells using Cas9 ribonucleoproteins K Schumann, S Lin, E Boyer, DR Simeonov, M Subramaniam, RE Gate, ... Proceedings of the National Academy of Sciences 112 (33), 10437-10442, 2015 | 848 | 2015 |
| Revisiting IL-2: Biology and therapeutic prospects AK Abbas, E Trotta, D R. Simeonov, A Marson, JA Bluestone Science immunology 3 (25), eaat1482, 2018 | 588 | 2018 |
| Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements MR Mumbach, AT Satpathy, EA Boyle, C Dai, BG Gowen, SW Cho, ... Nature genetics 49 (11), 1602-1612, 2017 | 492 | 2017 |
| Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 549 (7670), 111-115, 2017 | 308 | 2017 |
| GRIN2A mutation and early‐onset epileptic encephalopathy: personalized therapy with memantine TM Pierson, H Yuan, ED Marsh, K Fuentes‐Fajardo, DR Adams, ... Annals of clinical and translational neurology 1 (3), 190-198, 2014 | 300 | 2014 |
| Thymic regulatory T cells arise via two distinct developmental programs DL Owen, SA Mahmud, LE Sjaastad, JB Williams, JA Spanier, ... Nature immunology 20 (2), 195-205, 2019 | 248 | 2019 |
| CRISPR screen in regulatory T cells reveals modulators of Foxp3 JT Cortez, E Montauti, E Shifrut, J Gatchalian, Y Zhang, O Shaked, Y Xu, ... Nature 582 (7812), 416-420, 2020 | 203 | 2020 |
| DNA variations in oculocutaneous albinism: an updated mutation list and current outstanding issues in molecular diagnostics DR Simeonov, X Wang, C Wang, Y Sergeev, M Dolinska, M Bower, ... Human mutation 34 (6), 827-835, 2013 | 153 | 2013 |
| Functional CRISPR dissection of gene networks controlling human regulatory T cell identity K Schumann, SS Raju, M Lauber, S Kolb, E Shifrut, JT Cortez, N Skartsis, ... Nature immunology 21 (11), 1456-1466, 2020 | 80 | 2020 |
| miR-15/16 restrain memory T cell differentiation, cell cycle, and survival JD Gagnon, R Kageyama, HM Shehata, MS Fassett, DJ Mar, EJ Wigton, ... Cell reports 28 (8), 2169-2181. e4, 2019 | 73 | 2019 |
| Nitisinone improves eye and skin pigmentation defects in a mouse model of oculocutaneous albinism IF Onojafe, DR Adams, DR Simeonov, J Zhang, CC Chan, IM Bernardini, ... The Journal of clinical investigation 121 (10), 3914-3923, 2011 | 69 | 2011 |
| Exome sequencing and SNP analysis detect novel compound heterozygosity in fatty acid hydroxylase-associated neurodegeneration TM Pierson, DR Simeonov, M Sincan, DA Adams, T Markello, G Golas, ... European journal of human genetics 20 (4), 476-479, 2012 | 66 | 2012 |
| CRISPR-based tools in immunity DR Simeonov, A Marson Annual review of immunology 37 (1), 571-597, 2019 | 50 | 2019 |
| Protein complexes at the microtubule organizing center regulate bipolar spindle assembly AS Rodriguez, AN Killilea, J Batac, J Filopei, D Simeonov, I Lin, JL Paluh Cell Cycle 7 (9), 1246-1253, 2008 | 47 | 2008 |
| Defining disease, diagnosis, and translational medicine within a homeostatic perturbation paradigm: The national institutes of health undiagnosed diseases program experience T Gall, E Valkanas, C Bello, T Markello, C Adams, WP Bone, AJ Brandt, ... Frontiers in medicine 4, 62, 2017 | 42 | 2017 |
| Exome sequencing as a diagnostic tool in a case of undiagnosed juvenile-onset GM1-gangliosidosis TM Pierson, DA Adams, T Markello, G Golas, S Yang, M Sincan, ... Neurology 79 (2), 123-126, 2012 | 42 | 2012 |
| A divalent interaction between HPS1 and HPS4 is required for the formation of the biogenesis of lysosome-related organelle complex-3 (BLOC-3) C Carmona-Rivera, DR Simeonov, ND Cardillo, WA Gahl, CL Cadilla Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (3), 468-478, 2013 | 39 | 2013 |
| The mechanical properties of Drosophila jump muscle expressing wild-type and embryonic myosin isoforms CC Eldred, DR Simeonov, RA Koppes, C Yang, DT Corr, DM Swank Biophysical journal 98 (7), 1218-1226, 2010 | 38 | 2010 |
| VAR‐MD: A tool to analyze whole exome–genome variants in small human pedigrees with mendelian inheritance M Sincan, DR Simeonov, D Adams, TC Markello, TM Pierson, C Toro, ... Human mutation 33 (4), 593-598, 2012 | 32 | 2012 |
| Distinct Kinesin-14 mitotic mechanisms in spindle bipolarity DR Simeonov, K Kenny, L Seo, A Moyer, J Allen, JL Paluh Cell Cycle 8 (21), 3571-3583, 2009 | 29 | 2009 |