Thermal promotion of the cobalt catalyzed intramolecular Pauson-Khand reaction—An alternative experimental protocol for cyclopentenone synthesis DB Belanger, DJR O'Mahony, T Livinghouse Tetrahedron letters 39 (42), 7637-7640, 1998 | 114 | 1998 |
Hexacarbonyldicobalt-alkyne complexes as convenient Co2 (CO) 8 surrogates in the catalytic Pauson-Khand reaction DB Belanger, T Livinghouse Tetrahedron letters 39 (42), 7641-7644, 1998 | 95 | 1998 |
Discovery of imidazo [1, 2-a] pyrazine-based Aurora kinase inhibitors DB Belanger, PJ Curran, A Hruza, J Voigt, Z Meng, AK Mandal, ... Bioorganic & medicinal chemistry letters 20 (17), 5170-5174, 2010 | 74 | 2010 |
Imidazopyrazines as protein kinase inhibitors L Zhao, P Curran, D Belanger, B Hamann, P Reddy, K Paruch, T Guzi, ... US Patent App. 11/598,186, 2007 | 54 | 2007 |
(Alkylthio) alkynes as addends in the Co (0) catalyzed intramolecular Pauson-Khand reaction. Substituent driven enhancements of annulation efficiency and stereoselectivity BL Pagenkopf, DB Belanger, DJR O'Mahony, T Livinghouse Synthesis 2000 (07), 1009-1019, 2000 | 50 | 2000 |
Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core T Yu, JR Tagat, AD Kerekes, RJ Doll, Y Zhang, Y Xiao, S Esposite, ... ACS Medicinal Chemistry Letters 1 (5), 214-218, 2010 | 49 | 2010 |
On the Counterion Dependence of the Rhodium (I)-Catalysed [4+ 2] Cycloaddition-A Remarkable Accelerating Effect of the Hexafluoroantimonate Anion DJR O'Mahony, DB Belanger, T Livinghouse Synlett 1998 (04), 443-445, 1998 | 49 | 1998 |
Discovery of novel imidazo [1, 2-a] pyrazin-8-amines as Brk/PTK6 inhibitors H Zeng, DB Belanger, PJ Curran, GW Shipps Jr, H Miao, JB Bracken, ... Bioorganic & medicinal chemistry letters 21 (19), 5870-5875, 2011 | 40 | 2011 |
Substrate control of stereoselection in the rhodium (I) catalyzed intramolecular [4+ 2] cycloaddition reaction DJR O'Mahony, DB Belanger, T Livinghouse Organic & biomolecular chemistry 1 (12), 2038-2040, 2003 | 40 | 2003 |
The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors KE Rosner, Z Guo, P Orth, GW Shipps Jr, DB Belanger, TY Chan, ... Bioorganic & medicinal chemistry letters 20 (3), 1189-1193, 2010 | 35 | 2010 |
Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors DB Belanger, MJ Williams, PJ Curran, AK Mandal, Z Meng, MP Rainka, ... Bioorganic & medicinal chemistry letters 20 (22), 6739-6743, 2010 | 24 | 2010 |
Substituted pyrazolo [1, 5-a] pyrimidines as protein kinase inhibitors TJ Guzi, K Paruch, MP Dwyer, MA Siddiqui, PAP Reddy, DB Belanger, ... US Patent 7,563,798, 2009 | 24 | 2009 |
Imidazopyrazines as cyclin dependent kinase inhibitors TJ Guzi, K Paruch, MP Dwyer, L Zhao, PJ Curran, DB Belanger, ... US Patent 7,576,085, 2009 | 23 | 2009 |
Novel jnk inhibitors PAP Reddy, MA Siddiqui, PK Tadikonda, UF Mansoor, GW Shipps Jr, ... US Patent App. 12/519,733, 2010 | 21 | 2010 |
Substituted pyridines that are JNK inhibitors DB Belanger, MA Siddiqui, PJ Curran, B Hamann, L Zhao, PAP Reddy, ... US Patent 8,278,337, 2012 | 20 | 2012 |
Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitors Z Meng, BA Kulkarni, AD Kerekes, AK Mandal, SJ Esposite, DB Belanger, ... Bioorganic & medicinal chemistry letters 21 (1), 592-598, 2011 | 20 | 2011 |
Compounds for the treatment of inflammatory disorders Z Guo, P Orth, Z Zhu, RD Mazzola, TY Chan, HA Vaccaro, B McKittrick, ... US Patent 7,652,020, 2010 | 19 | 2010 |
Methods for inhibiting protein kinases T Guzi, K Paruch, M Dwyer, D Parry, L Zhao, P Curran, D Belanger, ... US Patent App. 11/598,188, 2007 | 19 | 2007 |
Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivity ME Voss, MP Rainka, M Fleming, LH Peterson, DB Belanger, MA Siddiqui, ... Bioorganic & medicinal chemistry letters 22 (10), 3544-3549, 2012 | 17 | 2012 |
Structure and activity relationships of tartrate-based TACE inhibitors D Li, J Popovici-Muller, DB Belanger, J Caldwell, C Dai, M David, ... Bioorganic & medicinal chemistry letters 20 (16), 4812-4815, 2010 | 17 | 2010 |