Theo dõi
Jon S. Thorson
Jon S. Thorson
Professor and Associate Dean for Research, University of Kentucky College of Pharmacy
Email được xác minh tại uky.edu - Trang chủ
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Antitumor antibiotics: Bleomycin, enediynes, and mitomycin
U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen
Chemical Reviews 105 (2), 739-758, 2005
6742005
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
MW Nowak, PC Kearney, JR Sampson, ME Saks, CG Labarca, ...
Science 268 (5209), 439-439, 1995
4521995
A comprehensive review of glycosylated bacterial natural products
SI Elshahawi, KA Shaaban, MK Kharel, JS Thorson
Chemical Society Reviews 44 (21), 7591-7697, 2015
4352015
A genomics-guided approach for discovering and expressing cryptic metabolic pathways
E Zazopoulos, K Huang, A Staffa, W Liu, BO Bachmann, K Nonaka, ...
Nature Biotechnology 21 (2), 187-190, 2003
4122003
Structure, activity, synthesis and biosynthesis of aryl-C-glycosides
T Bililign, BR Griffith, JS Thorson
Natural Product Reports 22 (6), 742-760, 2005
3822005
The calicheamicin gene cluster and its iterative type I enediyne PKS
J Ahlert, E Shepard, N Lomovskaya, E Zazopoulos, A Staffa, ...
Science 297 (5584), 1173-1176, 2002
3722002
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria
H Liu, JS Thorson
Annual Reviews in Microbiology 48 (1), 223-256, 1994
3551994
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions
C Zhang, BR Griffith, Q Fu, C Albermann, X Fu, IK Lee, L Li, JS Thorson
Science 313 (5791), 1291-1294, 2006
3322006
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution
GJ Williams, C Zhang, JS Thorson
Nature Chemical Biology 3 (10), 657-662, 2007
3182007
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization
JM Langenhan, NR Peters, IA Guzei, FM Hoffmann, JS Thorson
Proceedings of the National Academy of Sciences 102 (35), 12305-12310, 2005
2982005
Enzymatic methods for glyco (diversification/randomization) of drugs and small molecules
RW Gantt, P Peltier-Pain, JS Thorson
Natural Product Reports 28 (11), 1811-1853, 2011
2812011
Antibiotic optimization via in vitro glycorandomization
X Fu, C Albermann, J Jiang, J Liao, C Zhang, JS Thorson
Nature Biotechnology 21 (12), 1467-1469, 2003
2792003
Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites
JS Thorson, TJ Hosted Jr, J Jiang, JB Biggins, J Ahlert
Current Organic Chemistry 5 (2), 139-167, 2001
2212001
Understanding and exploiting nature's chemical arsenal: The past, present and future of calicheamicin research
JS Thorson, EL Sievers, J Ahlert, E Shepard, RE Whitwam, KC Onwueme, ...
Current Pharmaceutical Design 6 (18), 1841-1879, 2000
2192000
‘Sweetening’natural products via glycorandomization
BR Griffith, JM Langenhan, JS Thorson
Current Opinion in Biotechnology 16 (6), 622-630, 2005
1892005
Enzymatic tools for engineering natural product glycosylation
S Blanchard, JS Thorson
Current Opinion in Chemical Biology 10 (3), 263-271, 2006
1872006
Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation
A Chang, S Singh, GN Phillips Jr, JS Thorson
Current Opinion in Biotechnology 22 (6), 800-808, 2011
1862011
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides
HC Losey, J Jiang, JB Biggins, M Oberthür, XY Ye, SD Dong, D Kahne, ...
Chemistry & Biology 9 (12), 1305-1314, 2002
1842002
Neoglycorandomization and chemoenzymatic glycorandomization: Two complementary tools for natural product diversification
JM Langenhan, BR Griffith, JS Thorson
Journal of Natural Products 68 (11), 1696-1711, 2005
1792005
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization
WA Barton, J Lesniak, JB Biggins, PD Jeffrey, J Jiang, KR Rajashankar, ...
Nature Structural Biology 8 (6), 545-551, 2001
1642001
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