Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (∗) S Zhang, J Han, MA Sells, J Chernoff, UG Knaus, RJ Ulevitch, GM Bokoch Journal of Biological Chemistry 270 (41), 23934-23936, 1995 | 933 | 1995 |
Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases KD Martyn, LM Frederick, K Von Loehneysen, MC Dinauer, UG Knaus Cellular signalling 18 (1), 69-82, 2006 | 926 | 2006 |
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells MA Sells, UG Knaus, S Bagrodia, DM Ambrose, GM Bokoch, J Chernoff Current biology 7 (3), 202-210, 1997 | 888 | 1997 |
Toll-like receptor 2–mediated NF-κB activation requires a Rac1-dependent pathway L Arbibe, JP Mira, N Teusch, L Kline, M Guha, N Mackman, PJ Godowski, ... Nature immunology 1 (6), 533-540, 2000 | 844 | 2000 |
Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2 UG Knaus, PG Heyworth, T Evans, JT Curnutte, GM Bokoch Science 254 (5037), 1512-1515, 1991 | 830 | 1991 |
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b A Schnelzer, D Prechtel, U Knaus, K Dehne, M Gerhard, H Graeff, ... Oncogene 19 (26), 3013-3020, 2000 | 555 | 2000 |
NADPH oxidases: not just for leukocytes anymore! GM Bokoch, UG Knaus Trends in biochemical sciences 28 (9), 502-508, 2003 | 504 | 2003 |
Regulation of human leukocyte p21-activated kinases through G protein—coupled receptors UG Knaus, S Morris, HJ Dong, J Chernoff, GM Bokoch Science 269 (5221), 221-223, 1995 | 496 | 1995 |
Interaction of the Nck adapter protein with p21-activated kinase (PAK1) GM Bokoch, Y Wang, BP Bohl, MA Sells, LA Quilliam, UG Knaus Journal of Biological Chemistry 271 (42), 25746-25749, 1996 | 424 | 1996 |
Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway JP Mira, V Benard, J Groffen, LC Sanders, UG Knaus Proceedings of the National Academy of Sciences 97 (1), 185-189, 2000 | 354 | 2000 |
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 341 | 2017 |
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion AY Chan, SJ Coniglio, Y Chuang, D Michaelson, UG Knaus, MR Philips, ... Oncogene 24 (53), 7821-7829, 2005 | 313 | 2005 |
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling I Al Ghouleh, NKH Khoo, UG Knaus, KK Griendling, RM Touyz, ... Free Radical Biology and Medicine 51 (7), 1271-1288, 2011 | 296 | 2011 |
A GTPase-independent mechanism of p21-activated kinase activation: regulation by sphingosine and other biologically active lipids GM Bokoch, AM Reilly, RH Daniels, CC King, A Olivera, S Spiegel, ... Journal of Biological Chemistry 273 (14), 8137-8144, 1998 | 287 | 1998 |
ROS in gastrointestinal inflammation: rescue or sabotage? G Aviello, UG Knaus British journal of pharmacology 174 (12), 1704-1718, 2017 | 280 | 2017 |
The p21rac/cdc42-activated kinases (paks) UG Knaus, GM Bokoch The international journal of biochemistry & cell biology 30 (8), 857-862, 1998 | 255 | 1998 |
Rac GTPase interacts specifically with phosphatidylinositol 3-kinase GM Bokoch, CJ Vlahos, Y Wang, UG Knaus, AE Traynor-Kaplan Biochemical Journal 315 (3), 775-779, 1996 | 248 | 1996 |
NADPH oxidases and ROS signaling in the gastrointestinal tract G Aviello, UG Knaus Mucosal immunology 11 (4), 1011-1023, 2018 | 215 | 2018 |
Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. UG Knaus, PG Heyworth, BT Kinsella, JT Curnutte, GM Bokoch Journal of Biological Chemistry 267 (33), 23575-23582, 1992 | 210 | 1992 |
GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. TH Chuang, X Xu, UG Knaus, MJ Hart, GM Bokoch Journal of Biological Chemistry 268 (2), 775-778, 1993 | 185 | 1993 |