Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion V Lyssenko, CLF Nagorny, MR Erdos, N Wierup, A Jonsson, P Spégel, ... Nature genetics 41 (1), 82-88, 2009 | 888 | 2009 |
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease M Lundblad, M Andersson, C Winkler, D Kirik, N Wierup, MA Cenci European Journal of Neuroscience 15 (1), 120-132, 2002 | 802 | 2002 |
The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas N Wierup, H Svensson, H Mulder, F Sundler Regulatory peptides 107 (1-3), 63-69, 2002 | 706 | 2002 |
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes MD Nitert, T Dayeh, P Volkov, T Elgzyri, E Hall, E Nilsson, BT Yang, ... Diabetes 61 (12), 3322-3332, 2012 | 478 | 2012 |
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin KL Egerod, MS Engelstoft, KV Grunddal, MK Nøhr, A Secher, I Sakata, ... Endocrinology 153 (12), 5782-5795, 2012 | 357 | 2012 |
Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes AS Axelsson, E Tubbs, B Mecham, S Chacko, HA Nenonen, Y Tang, ... Science translational medicine 9 (394), eaah4477, 2017 | 332 | 2017 |
Orexin loss in Huntington's disease Å Petersén, J Gil, MLC Maat-Schieman, M Björkqvist, H Tanila, IM Araujo, ... Human molecular genetics 14 (1), 39-47, 2005 | 313 | 2005 |
Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells N Wierup, S Yang, RJ McEvilly, H Mulder, F Sundler Journal of Histochemistry & Cytochemistry 52 (3), 301-310, 2004 | 296 | 2004 |
Increased melatonin signaling is a risk factor for type 2 diabetes T Tuomi, CLF Nagorny, P Singh, H Bennet, Q Yu, I Alenkvist, B Isomaa, ... Cell metabolism 23 (6), 1067-1077, 2016 | 282 | 2016 |
TCF7L2 is a master regulator of insulin production and processing Y Zhou, SY Park, J Su, K Bailey, E Ottosson-Laakso, L Shcherbina, ... Human molecular genetics 23 (24), 6419-6431, 2014 | 251 | 2014 |
A Central Role for GRB10 in Regulation of Islet Function in Man I Prokopenko, W Poon, R Maegi, R Prasad B, SA Salehi, P Almgren, ... PLoS genetics 10 (4), e1004235, 2014 | 189 | 2014 |
Capsaicin‐sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type … DX Gram, B Ahrén, I Nagy, UB Olsen, CL Brand, F Sundler, R Tabanera, ... European Journal of Neuroscience 25 (1), 213-223, 2007 | 184 | 2007 |
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient β-cell mass and exocytosis M Björkqvist, M Fex, E Renström, N Wierup, Å Petersén, J Gil, K Bacos, ... Human molecular genetics 14 (5), 565-574, 2005 | 177 | 2005 |
The islet ghrelin cell N Wierup, F Sundler, RS Heller Journal of molecular endocrinology 52 (1), R35-R49, 2014 | 166 | 2014 |
Increased metabolism in the R6/2 mouse model of Huntington’s disease JMM van der Burg, K Bacos, NI Wood, A Lindqvist, N Wierup, B Woodman, ... Neurobiology of disease 29 (1), 41-51, 2008 | 161 | 2008 |
Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects M Riva, MD Nitert, U Voss, R Sathanoori, A Lindqvist, C Ling, N Wierup Cell and tissue research 346, 393-405, 2011 | 127 | 2011 |
CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight N Wierup, WG Richards, AW Bannon, MJ Kuhar, B Ahrén, F Sundler Regulatory peptides 129 (1-3), 203-211, 2005 | 127 | 2005 |
Link between GIP and osteopontin in adipose tissue and insulin resistance E Ahlqvist, P Osmark, T Kuulasmaa, K Pilgaard, B Omar, C Brøns, ... Diabetes 62 (6), 2088-2094, 2013 | 124 | 2013 |
Gastrointestinal dysfunction contributes to weight loss in Huntington's disease mice JMM van der Burg, A Winqvist, NA Aziz, MLC Maat-Schieman, RAC Roos, ... Neurobiology of disease 44 (1), 1-8, 2011 | 122 | 2011 |
Cocaine‐and amphetamine‐regulated transcript: distribution and function in rat gastrointestinal tract E Ekblad, M Kuhar, N Wierup, F Sundler Neurogastroenterology & Motility 15 (5), 545-557, 2003 | 119 | 2003 |