TMC1 forms the pore of mechanosensory transduction channels in vertebrate inner ear hair cells B Pan, N Akyuz, XP Liu, Y Asai, C Nist-Lund, K Kurima, BH Derfler, ... Neuron 99 (4), 736-753. e6, 2018 | 313 | 2018 |
Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss B György, C Nist-Lund, B Pan, Y Asai, KD Karavitaki, BP Kleinstiver, ... Nature medicine 25 (7), 1123-1130, 2019 | 204 | 2019 |
Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders CA Nist-Lund, B Pan, A Patterson, Y Asai, T Chen, W Zhou, H Zhu, ... Nature communications 10 (1), 236, 2019 | 156 | 2019 |
A fluorinated alkoxyaluminate electrolyte for magnesium-ion batteries JT Herb, CA Nist-Lund, CB Arnold ACS Energy Letters 1 (6), 1227-1232, 2016 | 143 | 2016 |
Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP. B J Lee, C Nist-Lund, P Solanes, H Goldberg, J Wu, B Pan, BL Schneider, ... Hearing research 394, 107882, 2020 | 73 | 2020 |
Single and dual vector gene therapy with AAV9-PHP. B rescues hearing in Tmc1 mutant mice J Wu, P Solanes, C Nist-Lund, S Spataro, O Shubina-Oleinik, I Marcovich, ... Molecular Therapy 29 (3), 973-988, 2021 | 58 | 2021 |
Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss O Shubina-Oleinik, C Nist-Lund, C French, S Rockowitz, AE Shearer, ... Science advances 7 (51), eabi7629, 2021 | 46 | 2021 |
Direct delivery of antisense oligonucleotides to the middle and inner ear improves hearing and balance in Usher mice JJ Lentz, B Pan, A Ponnath, CM Tran, C Nist-Lund, A Galvin, H Goldberg, ... Molecular Therapy 28 (12), 2662-2676, 2020 | 40 | 2020 |
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175 W Zheng, C Shen, L Wang, S Rawson, WJ Xie, C Nist-Lund, J Wu, Z Shen, ... Science advances 8 (12), eabm1568, 2022 | 35 | 2022 |
A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs WH van der Valk, ESA van Beelen, MR Steinhart, C Nist-Lund, D Osorio, ... Cell reports 42 (6), 2023 | 33 | 2023 |
Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1 Y Asai, B Pan, C Nist-Lund, A Galvin, AN Lukashkin, VA Lukashkina, ... Scientific Reports 8 (1), 12124, 2018 | 28 | 2018 |
A fluorinated dialkoxide-based magnesium-ion electrolyte JT Herb, CA Nist-Lund, CB Arnold Journal of Materials Chemistry A 5 (17), 7801-7805, 2017 | 24 | 2017 |
Advancements in inner ear development, regeneration, and repair through otic organoids C Nist-Lund, J Kim, KR Koehler Current opinion in genetics & development 76, 101954, 2022 | 12 | 2022 |
Improving halide-containing magnesium-ion electrolyte performance via sterically hindered alkoxide ligands CA Nist-Lund, JT Herb, CB Arnold Journal of Power Sources 362, 308-314, 2017 | 12 | 2017 |
Structural effects of magnesium dialkoxides as precursors for magnesium-ion electrolytes JT Herb, C Nist-Lund, J Schwartz, CB Arnold ECS Electrochemistry Letters 4 (6), A49, 2015 | 12 | 2015 |
Electrolytes for magnesium-ion batteries J Herb, C Arnold, C Nist-Lund US Patent App. 15/084,862, 2016 | 7 | 2016 |
Mapping oto-pharyngeal development in a human inner ear organoid model MR Steinhart, WH van der Valk, D Osorio, SA Serdy, J Zhang, C Nist-Lund, ... Development 150 (19), dev201871, 2023 | 6 | 2023 |
A fluorinated alkoxyaluminate electrolyte for magnesium-ion batteries. ACS Energy Lett 1: 1227–1232 JT Herb, CA Nist-Lund, CB Arnold | 6 | 2016 |
Delivery of CRISPR/Cas9 using AAV-PHP. B in the inner ear leads to allele-specific inactivation of the mutated Tmc1 allele and protects auditory function in Beethoven mice P Solanes, S Spataro, Y Asai, B Pan, CA Nist-Lund, JR Holt, ... Human Gene Therapy 30 (11), A106-A107, 2019 | 2 | 2019 |
Allele-specific gene disruption through discrimination of a single base change by S. aureus Cas9-KKH prevents progressive hearing loss after AAV-mediated gene delivery B Gyorgy, C Nist-Lund, B Pan, Y Asai, KD Karavitaki, BP Kleinstiver, ... Human Gene Therapy 30 (11), A11-A12, 2019 | 1 | 2019 |