| Tau protein liquid–liquid phase separation can initiate tau aggregation S Wegmann, B Eftekharzadeh, K Tepper, KM Zoltowska, RE Bennett, ... The EMBO journal 37 (7), e98049, 2018 | 972 | 2018 |
| LRP1 is a master regulator of tau uptake and spread JN Rauch, G Luna, E Guzman, M Audouard, C Challis, YE Sibih, ... Nature 580 (7803), 381-385, 2020 | 498 | 2020 |
| Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ... Neuron 99 (5), 925-940. e7, 2018 | 422 | 2018 |
| Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo MA Busche, S Wegmann, S Dujardin, C Commins, J Schiantarelli, ... Nature neuroscience 22 (1), 57-64, 2019 | 418 | 2019 |
| Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain S Takeda, S Wegmann, H Cho, SL DeVos, C Commins, AD Roe, ... Nature communications 6 (1), 8490, 2015 | 391 | 2015 |
| Local nucleation of microtubule bundles through tubulin concentration into a condensed tau phase A Hernández-Vega, M Braun, L Scharrel, M Jahnel, S Wegmann, ... Cell reports 20 (10), 2304-2312, 2017 | 371 | 2017 |
| A current view on Tau protein phosphorylation in Alzheimer's disease S Wegmann, J Biernat, E Mandelkow Current opinion in neurobiology 69, 131-138, 2021 | 349 | 2021 |
| Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease AM Pooler, M Polydoro, EA Maury, SB Nicholls, SM Reddy, S Wegmann, ... Acta neuropathologica communications 3, 1-11, 2015 | 271 | 2015 |
| Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo KV Kuchibhotla, S Wegmann, KJ Kopeikina, J Hawkes, N Rudinskiy, ... Proceedings of the National Academy of Sciences 111 (1), 510-514, 2014 | 228 | 2014 |
| Atypical, non-standard functions of the microtubule associated Tau protein I Sotiropoulos, MC Galas, JM Silva, E Skoulakis, S Wegmann, MB Maina, ... Acta neuropathologica communications 5, 1-11, 2017 | 216 | 2017 |
| The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush S Wegmann, ID Medalsy, E Mandelkow, DJ Müller Proceedings of the National Academy of Sciences 110 (4), E313-E321, 2013 | 214 | 2013 |
| Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice B Caballero, M Bourdenx, E Luengo, A Diaz, PD Sohn, XU Chen, C Wang, ... Nature communications 12 (1), 2238, 2021 | 172 | 2021 |
| Oligomer formation of tau protein hyperphosphorylated in cells K Tepper, J Biernat, S Kumar, S Wegmann, T Timm, S Hübschmann, ... Journal of Biological Chemistry 289 (49), 34389-34407, 2014 | 170 | 2014 |
| Experimental evidence for the age dependence of tau protein spread in the brain S Wegmann, RE Bennett, L Delorme, AB Robbins, M Hu, D MacKenzie, ... Science advances 5 (6), eaaw6404, 2019 | 148 | 2019 |
| Human Tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability S Wegmann, YJ Jung, S Chinnathambi, EM Mandelkow, E Mandelkow, ... Journal of Biological Chemistry 285 (35), 27302-27313, 2010 | 138 | 2010 |
| Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity S Wegmann, EA Maury, MJ Kirk, L Saqran, A Roe, SL DeVos, S Nicholls, ... The EMBO journal 34 (24), 3028-3041, 2015 | 131 | 2015 |
| Multiparametric high-resolution imaging of native proteins by force-distance curve–based AFM M Pfreundschuh, D Martinez-Martin, E Mulvihill, S Wegmann, DJ Muller nature protocols 9 (5), 1113-1130, 2014 | 131 | 2014 |
| Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets AM Pooler, M Polydoro, S Wegmann, SB Nicholls, TL Spires-Jones, ... Alzheimer's research & therapy 5, 1-8, 2013 | 128 | 2013 |
| TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau PEA Ash, S Lei, J Shattuck, S Boudeau, Y Carlomagno, M Medalla, ... Proceedings of the National Academy of Sciences 118 (9), e2014188118, 2021 | 121 | 2021 |
| Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients S Takeda, C Commins, SL DeVos, CK Nobuhara, S Wegmann, AD Roe, ... Annals of neurology 80 (3), 355-367, 2016 | 119 | 2016 |