| Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 … C Allemani, T Matsuda, V Di Carlo, R Harewood, M Matz, M Nikšić, ... The Lancet 391 (10125), 1023-1075, 2018 | 5243 | 2018 |
| Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin S Valleix, JD Gillmore, F Bridoux, PP Mangione, A Dogan, B Nedelec, ... New England Journal of Medicine 366 (24), 2276-2283, 2012 | 229 | 2012 |
| The solution structure of human β2‐microglobulin reveals the prodromes of its amyloid transition G Verdone, A Corazza, P Viglino, F Pettirossi, S Giorgetti, P Mangione, ... Protein Science 11 (3), 487-499, 2002 | 212 | 2002 |
| A partially structured species of β2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis F Chiti, E De Lorenzi, S Grossi, P Mangione, S Giorgetti, G Caccialanza, ... Journal of Biological Chemistry 276 (50), 46714-46721, 2001 | 172 | 2001 |
| A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis J Marcoux, PP Mangione, R Porcari, MT Degiacomi, G Verona, GW Taylor, ... EMBO molecular medicine 7 (10), 1337-1349, 2015 | 169 | 2015 |
| Collagen plays an active role in the aggregation of β2-microglobulin under physiopathological conditions of dialysis-related amyloidosis A Relini, C Canale, S De Stefano, R Rolandi, S Giorgetti, M Stoppini, ... Journal of Biological Chemistry 281 (24), 16521-16529, 2006 | 166 | 2006 |
| Targeting amyloid aggregation: an overview of strategies and mechanisms S Giorgetti, C Greco, P Tortora, FA Aprile International journal of molecular sciences 19 (9), 2677, 2018 | 165 | 2018 |
| Structure, function and amyloidogenic propensity of apolipoprotein AI L Obici, G Franceschini, L Calabresi, S Giorgetti, M Stoppini, G Merlini, ... Amyloid 13 (4), 191-205, 2006 | 165 | 2006 |
| Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic β2-microglobulin variant K Domanska, S Vanderhaegen, V Srinivasan, E Pardon, F Dupeux, ... Proceedings of the National Academy of Sciences 108 (4), 1314-1319, 2011 | 153 | 2011 |
| Heparin strongly enhances the formation of β2-microglobulin amyloid fibrils in the presence of type I collagen A Relini, S De Stefano, S Torrassa, O Cavalleri, R Rolandi, A Gliozzi, ... Journal of Biological Chemistry 283 (8), 4912-4920, 2008 | 145 | 2008 |
| Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis PP Mangione, R Porcari, JD Gillmore, P Pucci, M Monti, M Porcari, ... Proceedings of the National Academy of Sciences 111 (4), 1539-1544, 2014 | 138 | 2014 |
| Italian cancer figures, report 2012: cancer in children and adolescents AIRTUM Working Group, AIEOP Working Group Epidemiologia e prevenzione 37 (1 Suppl 1), 1-225, 2013 | 137* | 2013 |
| Detection of two partially structured species in the folding process of the amyloidogenic protein β2-microglobulin F Chiti, P Mangione, A Andreola, S Giorgetti, M Stefani, CM Dobson, ... Journal of molecular biology 307 (1), 379-391, 2001 | 134 | 2001 |
| ITALIAN CANCER FIGURES-REPORT 2015: The burden of rare cancers in Italy= I TUMORI IN ITALIA-RAPPORTO 2015: I tumori rari in Italia S Busco, C Buzzoni, S Mallone, A Trama, M Castaing, F Bella, R Amodio, ... Epidemiologia e prevenzione 40 (1, suppl. 2), 1-120, 2016 | 127 | 2016 |
| Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils*♦ S Giorgetti, S Raimondi, K Pagano, A Relini, M Bucciantini, A Corazza, ... Journal of Biological Chemistry 286 (3), 2121-2131, 2011 | 124 | 2011 |
| The workings of the amyloid diseases V Bellotti, M Nuvolone, S Giorgetti, L Obici, G Palladini, P Russo, ... Annals of medicine 39 (3), 200-207, 2007 | 116 | 2007 |
| Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein AI A Andreola, V Bellotti, S Giorgetti, P Mangione, L Obici, M Stoppini, ... Journal of Biological Chemistry 278 (4), 2444-2451, 2003 | 111 | 2003 |
| The controlling roles of Trp60 and Trp95 in β2-microglobulin function, folding and amyloid aggregation properties G Esposito, S Ricagno, A Corazza, E Rennella, D Gümral, MC Mimmi, ... Journal of molecular biology 378 (4), 887-897, 2008 | 109 | 2008 |
| Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin PP Mangione, G Esposito, A Relini, S Raimondi, R Porcari, S Giorgetti, ... Journal of Biological Chemistry 288 (43), 30917-30930, 2013 | 106 | 2013 |
| Plasminogen activation triggers transthyretin amyloidogenesis in vitro PP Mangione, G Verona, A Corazza, J Marcoux, D Canetti, S Giorgetti, ... Journal of Biological Chemistry 293 (37), 14192-14199, 2018 | 96 | 2018 |