Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 14016* | 2021 |
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ... Science 357 (6357), 1255-1261, 2017 | 834 | 2017 |
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression P Reinhardt, B Schmid, LF Burbulla, DC Schöndorf, L Wagner, M Glatza, ... Cell stem cell 12 (3), 354-367, 2013 | 567 | 2013 |
Functional impairment in miro degradation and mitophagy is a shared feature in familial and sporadic Parkinson’s disease CH Hsieh, A Shaltouki, AE Gonzalez, AB da Cruz, LF Burbulla, ... Cell stem cell 19 (6), 709-724, 2016 | 469 | 2016 |
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1 G Krebiehl, S Ruckerbauer, LF Burbulla, N Kieper, B Maurer, J Waak, ... PloS one 5 (2), e9367, 2010 | 453 | 2010 |
Activation of β-glucocerebrosidase reduces pathological α-synuclein and restores lysosomal function in Parkinson's patient midbrain neurons JR Mazzulli, F Zunke, T Tsunemi, NJ Toker, S Jeon, LF Burbulla, ... Journal of Neuroscience 36 (29), 7693-7706, 2016 | 290 | 2016 |
Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis LF Burbulla, C Schelling, H Kato, D Rapaport, D Woitalla, C Schiesling, ... Human molecular genetics 19 (22), 4437-4452, 2010 | 162 | 2010 |
Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain. SM Graves, Z Xie, E Zampese, KA Stout, RA Tai, SE Schwarzschild, ... Nature Neuroscience, 1-6, 2019 | 153 | 2019 |
A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson’s disease LF Burbulla, S Jeon, J Zheng, P Song, RB Silverman, D Krainc Science translational medicine 11 (514), eaau6870, 2019 | 106 | 2019 |
Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1 LF Burbulla, JC Fitzgerald, K Stegen, J Westermeier, AK Thost, H Kato, ... Cell death & disease 5 (4), e1180-e1180, 2014 | 106 | 2014 |
Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function MJ Kim, S Jeon, LF Burbulla, D Krainc Human molecular genetics 27 (11), 1972-1988, 2018 | 81 | 2018 |
Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease LF Burbulla, R Krüger Journal of the neurological sciences 306 (1-2), 1-8, 2011 | 79 | 2011 |
Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells P Seibler, LF Burbulla, M Dulovic, S Zittel, J Heine, T Schmidt, F Rudolph, ... Brain 141 (10), 3052-3064, 2018 | 73 | 2018 |
Balance is the challenge–the impact of mitochondrial dynamics in Parkinson’s disease LF Burbulla, G Krebiehl, R Krüger European journal of clinical investigation 40 (11), 1048-1060, 2010 | 62 | 2010 |
Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders RM Wise, A Wagener, UM Fietzek, T Klopstock, EV Mosharov, FA Zucca, ... Neurobiology of Disease 175, 105920, 2022 | 56 | 2022 |
The convergence of alpha-synuclein, mitochondrial, and lysosomal pathways in vulnerability of midbrain dopaminergic neurons in Parkinson’s disease G Minakaki, D Krainc, LF Burbulla Frontiers in Cell and Developmental Biology 8, 580634, 2020 | 55 | 2020 |
Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson’s disease model J Zhu, N Vereshchagina, V Sreekumar, LF Burbulla, AC Costa, KJ Daub, ... PloS one 8 (12), e83714, 2013 | 53 | 2013 |
Genome-wide association and meta-analysis of age at onset in Parkinson disease: evidence from the COURAGE-PD consortium S Grover, AA Kumar Sreelatha, L Pihlstrom, C Domenighetti, C Schulte, ... Neurology 99 (7), e698-e710, 2022 | 50 | 2022 |
Variants in Miro1 cause alterations of ER-mitochondria contact sites in fibroblasts from Parkinson’s disease patients C Berenguer-Escuder, D Grossmann, F Massart, P Antony, LF Burbulla, ... Journal of clinical medicine 8 (12), 2226, 2019 | 48 | 2019 |
Gelator length precisely tunes supramolecular hydrogel stiffness and neuronal phenotype in 3D culture JM Godbe, R Freeman, LF Burbulla, J Lewis, D Krainc, SI Stupp ACS biomaterials science & engineering 6 (2), 1196-1207, 2020 | 47 | 2020 |