Polyketide biosynthesis: a millennium review J Staunton, KJ Weissman Natural product reports 18 (4), 380-416, 2001 | 2193 | 2001 |
Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 895 | 2021 |
Combinatorial biosynthesis of reduced polyketides KJ Weissman, PF Leadlay Nature reviews microbiology 3 (12), 925-936, 2005 | 616 | 2005 |
Complete genome sequence of the myxobacterium Sorangium cellulosum S Schneiker, O Perlova, O Kaiser, K Gerth, A Alici, MO Altmeyer, D Bartels, ... Nature biotechnology 25 (11), 1281-1289, 2007 | 492 | 2007 |
Myxobacterial secondary metabolites: bioactivities and modes-of-action KJ Weissman, R Müller Natural product reports 27 (9), 1276-1295, 2010 | 383 | 2010 |
The structure of docking domains in modular polyketide synthases RW Broadhurst, D Nietlispach, MP Wheatcroft, PF Leadlay, KJ Weissman Chemistry & biology 10 (8), 723-731, 2003 | 271 | 2003 |
The structural biology of biosynthetic megaenzymes KJ Weissman Nature Chemical Biology 11 (9), 660-670, 2015 | 262 | 2015 |
Introduction to polyketide biosynthesis KJ Weissman Methods in enzymology 459, 3-16, 2009 | 192 | 2009 |
Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology KJ Weissman Natural product reports 33 (2), 203-230, 2016 | 185 | 2016 |
A brief tour of myxobacterial secondary metabolism KJ Weissman, R Müller Bioorganic & medicinal chemistry 17 (6), 2121-2136, 2009 | 176 | 2009 |
Protein–protein interactions in multienzyme megasynthetases KJ Weissman, R Müller ChemBioChem 9 (6), 826-848, 2008 | 168 | 2008 |
Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases AP Siskos, A Baerga-Ortiz, S Bali, V Stein, H Mamdani, D Spiteller, ... Chemistry & biology 12 (10), 1145-1153, 2005 | 148 | 2005 |
Mutasynthesis–uniting chemistry and genetics for drug discovery KJ Weissman Trends in biotechnology 25 (4), 139-142, 2007 | 143 | 2007 |
Pretubulysin, a potent and chemically accessible tubulysin precursor from Angiococcus disciformis A Ullrich, Y Chai, D Pistorius, YA Elnakady, JE Herrmann, KJ Weissman, ... Angewandte Chemie International Edition 48 (24), 4422-4425, 2009 | 139 | 2009 |
Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137 BM Harvey, T Mironenko, Y Sun, H Hong, Z Deng, PF Leadlay, ... Chemistry & biology 14 (6), 703-714, 2007 | 136 | 2007 |
The molecular basis of Celmer's rules: the stereochemistry of the condensation step in chain extension on the erythromycin polyketide synthase KJ Weissman, M Timoney, M Bycroft, P Grice, U Hanefeld, J Staunton, ... Biochemistry 36 (45), 13849-13855, 1997 | 129 | 1997 |
Multienzyme docking in hybrid megasynthetases CD Richter, D Nietlispach, RW Broadhurst, KJ Weissman Nature Chemical Biology 4 (1), 75-81, 2008 | 110 | 2008 |
Uncovering the structures of modular polyketide synthases KJ Weissman Natural product reports 32 (3), 436-453, 2015 | 107 | 2015 |
Myxochelin biosynthesis: direct evidence for two-and four-electron reduction of a carrier protein-bound thioester Y Li, KJ Weissman, R Müller Journal of the American Chemical Society 130 (24), 7554-7555, 2008 | 105 | 2008 |
Artificial metalloenzymes for enantioselective catalysis: Recent advances C Letondor, TR Ward ChemBioChem 7 (12), 1845-1852, 2006 | 104 | 2006 |