| A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, ... Science 335 (6070), 823-828, 2012 | 1428 | 2012 |
| The UK10K project identifies rare variants in health and disease Statistics group Ciampi Antonio 8 Greenwood Celia MT (co-chair) 7 8 14 19 ... Nature 526 (7571), 82-90, 2015 | 1140 | 2015 |
| Enhanced detection of circulating tumor DNA by fragment size analysis F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, ... Science translational medicine 10 (466), eaat4921, 2018 | 944 | 2018 |
| Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ... Science 342 (6160), 866-871, 2013 | 680 | 2013 |
| Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 T Cooks, IS Pateras, LM Jenkins, KM Patel, AI Robles, J Morris, ... Nature communications 9 (1), 771, 2018 | 479 | 2018 |
| High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development D Lin, AW Wyatt, H Xue, Y Wang, X Dong, A Haegert, R Wu, S Brahmbhatt, ... Cancer research 74 (4), 1272-1283, 2014 | 417 | 2014 |
| Direct arylation of thiazoles on water GL Turner, JA Morris, MF Greaney Angewandte Chemie-International Edition 46 (42), 7996-8000, 2007 | 362 | 2007 |
| Effective drug combinations in breast, colon and pancreatic cancer cells P Jaaks, EA Coker, DJ Vis, O Edwards, EF Carpenter, SM Leto, L Dwane, ... Nature 603 (7899), 166-173, 2022 | 322 | 2022 |
| Ligand-promoted C3-selective arylation of pyridines with Pd catalysts: gram-scale synthesis of (±)-preclamol M Ye, GL Gao, AJF Edmunds, PA Worthington, JA Morris, JQ Yu Journal of the American Chemical Society 133 (47), 19090-19093, 2011 | 280 | 2011 |
| Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients F Mouliere, R Mair, D Chandrananda, F Marass, CG Smith, J Su, J Morris, ... EMBO molecular medicine 10 (12), e9323, 2018 | 173 | 2018 |
| ctDNA monitoring using patient-specific sequencing and integration of variant reads JCM Wan, K Heider, D Gale, S Murphy, E Fisher, F Mouliere, ... Science translational medicine 12 (548), eaaz8084, 2020 | 169 | 2020 |
| Pan-cancer proteomic map of 949 human cell lines E Gonçalves, RC Poulos, Z Cai, S Barthorpe, SS Manda, N Lucas, A Beck, ... Cancer cell 40 (8), 835-849. e8, 2022 | 136 | 2022 |
| optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants TS Shah, JZ Liu, JAB Floyd, JA Morris, N Wirth, JC Barrett, CA Anderson Bioinformatics 28 (12), 1598-1603, 2012 | 133 | 2012 |
| A robust protocol for Pd (ii)-catalyzed C-3 arylation of (1 H) indazoles and pyrazoles: total synthesis of nigellidine hydrobromide M Ye, AJF Edmunds, JA Morris, D Sale, Y Zhang, JQ Yu Chemical Science 4 (6), 2374-2379, 2013 | 121 | 2013 |
| Association of plasma and urinary mutant DNA with clinical outcomes in muscle invasive bladder cancer KM Patel, KE Van Der Vos, CG Smith, F Mouliere, D Tsui, J Morris, ... Scientific Reports 7 (1), 5554, 2017 | 114 | 2017 |
| Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors CG Smith, T Moser, F Mouliere, J Field-Rayner, M Eldridge, AL Riediger, ... Genome medicine 12, 1-17, 2020 | 105 | 2020 |
| Effects of collection and processing procedures on plasma circulating cell-free DNA from cancer patients B Risberg, DWY Tsui, H Biggs, ARVM de Almagro, SJ Dawson, ... The Journal of Molecular Diagnostics 20 (6), 883-892, 2018 | 99 | 2018 |
| Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens E Gonçalves, A Segura‐Cabrera, C Pacini, G Picco, FM Behan, P Jaaks, ... Molecular Systems Biology 16 (7), e9405, 2020 | 91 | 2020 |
| Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients F Mouliere, CG Smith, K Heider, J Su, Y van der Pol, M Thompson, ... EMBO Molecular Medicine 13 (8), e12881, 2021 | 86 | 2021 |
| Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer DWY Tsui, M Murtaza, ASC Wong, OM Rueda, CG Smith, ... EMBO molecular medicine 10 (6), e7945, 2018 | 69 | 2018 |
