Physiological and structural differences in spatially distinct subpopulations of cardiac mitochondria: influence of cardiac pathologies JM Hollander, D Thapa, DL Shepherd American Journal of Physiology-Heart and Circulatory Physiology 307 (1), H1-H14, 2014 | 203 | 2014 |
Proteomic alterations of distinct mitochondrial subpopulations in the type 1 diabetic heart: contribution of protein import dysfunction WA Baseler, ER Dabkowski, CL Williamson, TL Croston, D Thapa, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011 | 152 | 2011 |
miR-141 as a regulator of the mitochondrial phosphate carrier (Slc25a3) in the type 1 diabetic heart WA Baseler, D Thapa, R Jagannathan, ER Dabkowski, TL Croston, ... American Journal of Physiology-Cell Physiology 303 (12), C1244-C1251, 2012 | 132 | 2012 |
Translational regulation of the mitochondrial genome following redistribution of mitochondrial microRNA in the diabetic heart R Jagannathan, D Thapa, CE Nichols, DL Shepherd, JC Stricker, ... Circulation: Cardiovascular Genetics 8 (6), 785-802, 2015 | 129 | 2015 |
Functional deficiencies of subsarcolemmal mitochondria in the type 2 diabetic human heart TL Croston, D Thapa, AA Holden, KJ Tveter, SE Lewis, DL Shepherd, ... American Journal of Physiology-Heart and Circulatory Physiology 307 (1), H54-H65, 2014 | 96 | 2014 |
Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase WA Baseler, ER Dabkowski, R Jagannathan, D Thapa, CE Nichols, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2013 | 93 | 2013 |
Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway D Thapa, MW Stoner, M Zhang, B Xie, JR Manning, D Guimaraes, S Shiva, ... Redox biology 18, 25-32, 2018 | 92 | 2018 |
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA D Thapa, K Wu, MW Stoner, B Xie, M Zhang, JR Manning, Z Lu, JH Li, ... Journal of Biological Chemistry 293 (46), 17676-17684, 2018 | 82 | 2018 |
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart D Thapa, M Zhang, JR Manning, DA Guimarães, MW Stoner, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (2 …, 2017 | 82 | 2017 |
Transgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunction D Thapa, CE Nichols, SE Lewis, DL Shepherd, R Jagannathan, ... Journal of molecular and cellular cardiology 79, 212-223, 2015 | 79 | 2015 |
Adropin reduces blood glucose levels in mice by limiting hepatic glucose production D Thapa, B Xie, JR Manning, M Zhang, MW Stoner, BR Huckestein, ... Physiological reports 7 (8), e14043, 2019 | 62 | 2019 |
Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice D Thapa, B Xie, M Zhang, MW Stoner, JR Manning, BR Huckestein, ... Journal of molecular and cellular cardiology 129, 174-178, 2019 | 57 | 2019 |
GCN5L1/BLOS1 links acetylation, organelle remodeling, and metabolism I Scott, L Wang, K Wu, D Thapa, MN Sack Trends in cell biology 28 (5), 346-355, 2018 | 56 | 2018 |
Early detection of cardiac dysfunction in the type 1 diabetic heart using speckle-tracking based strain imaging DL Shepherd, CE Nichols, TL Croston, SL McLaughlin, AB Petrone, ... Journal of molecular and cellular cardiology 90, 74-83, 2016 | 53 | 2016 |
Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart TL Croston, DL Shepherd, D Thapa, CE Nichols, SE Lewis, ... Life sciences 93 (8), 313-322, 2013 | 49 | 2013 |
Reactive oxygen species damage drives cardiac and mitochondrial dysfunction following acute nano-titanium dioxide inhalation exposure CE Nichols, DL Shepherd, QA Hathaway, AJ Durr, D Thapa, A Abukabda, ... Nanotoxicology 12 (1), 32-48, 2018 | 48 | 2018 |
Cardiac and mitochondrial dysfunction following acute pulmonary exposure to mountaintop removal mining particulate matter CE Nichols, DL Shepherd, TL Knuckles, D Thapa, JC Stricker, ... American Journal of Physiology-Heart and Circulatory Physiology 309 (12 …, 2015 | 48 | 2015 |
Cardiac-specific deletion of GCN5L1 restricts recovery from ischemia-reperfusion injury JR Manning, D Thapa, M Zhang, MW Stoner, J Traba, CF McTiernan, ... Journal of molecular and cellular cardiology 129, 69-78, 2019 | 27 | 2019 |
Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling JR Manning, D Thapa, M Zhang, MW Stoner, J Traba, C Corey, S Shiva, ... Biochemical Journal 476 (12), 1713-1724, 2019 | 26 | 2019 |
Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol M Kerr, JJ Miller, D Thapa, S Stiewe, KN Timm, CNM Aparicio, I Scott, ... JCI insight 5 (17), e140326, 2020 | 25 | 2020 |