Cell-penetrating peptides—mechanisms of cellular uptake and generation of delivery systems S Trabulo, AL Cardoso, M Mano, MCP De Lima Pharmaceuticals 3 (4), 961-993, 2010 | 386 | 2010 |
Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms M Cioffi, S Trabulo, M Hidalgo, E Costello, W Greenhalf, M Erkan, J Kleeff, ... Clinical Cancer Research 21 (10), 2325-2337, 2015 | 228 | 2015 |
Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells E Lonardo, M Cioffi, P Sancho, Y Sanchez-Ripoll, SM Trabulo, J Dorado, ... PloS one 8 (10), e76518, 2013 | 188 | 2013 |
Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling A Balic, MD Sørensen, SM Trabulo, B Sainz, M Cioffi, CR Vieira, ... Molecular cancer therapeutics 13 (7), 1758-1771, 2014 | 170 | 2014 |
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells M Cioffi, SM Trabulo, Y Sanchez-Ripoll, I Miranda-Lorenzo, E Lonardo, ... Gut 64 (12), 1936-1948, 2015 | 149 | 2015 |
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression S Ottaviani, J Stebbing, AE Frampton, S Zagorac, J Krell, A de Giorgio, ... Nature communications 9 (1), 1845, 2018 | 127 | 2018 |
MiR-93 controls adiposity via inhibition of Sirt7 and Tbx3 M Cioffi, M Vallespinos-Serrano, SM Trabulo, PJ Fernandez-Marcos, ... Cell reports 12 (10), 1594-1605, 2015 | 114 | 2015 |
Multifunctionalized iron oxide nanoparticles for selective targeting of pancreatic cancer cells S Trabulo, A Aires, A Aicher, C Heeschen, AL Cortajarena Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (6), 1597-1605, 2017 | 106 | 2017 |
ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation L Dumartin, W Alrawashdeh, SM Trabulo, TP Radon, K Steiger, ... Oncogene 36 (22), 3094-3103, 2017 | 106 | 2017 |
Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology D Osuna de la Peña, SMD Trabulo, E Collin, Y Liu, S Sharma, M Tatari, ... Nature Communications 12 (1), 5623, 2021 | 95 | 2021 |
The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1 M Cioffi, SM Trabulo, M Vallespinos, D Raj, TB Kheir, ML Lin, J Begum, ... Oncotarget 8 (13), 21609-21625, 2017 | 77 | 2017 |
Roles of cell fusion, hybridization and polyploid cell formation in cancer metastasis I Shabo, J Svanvik, A Lindström, T Lechertier, S Trabulo, J Hulit, T Sparey, ... World journal of clinical oncology 11 (3), 121, 2020 | 72 | 2020 |
Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents S Trabulo, AM Cardoso, T Santos-Ferreira, AL Cardoso, S Simoes, ... Molecular pharmaceutics 8 (4), 1120-1131, 2011 | 68 | 2011 |
S4 (13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: Implications for cell internalization A Cardoso, S Trabulo, AL Cardoso, A Lorents, CM Morais, P Gomes, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (3), 877-888, 2012 | 57 | 2012 |
Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma M Alonso-Nocelo, L Ruiz-Cañas, P Sancho, K Görgülü, S Alcalá, ... Gut 72 (2), 345-359, 2023 | 52 | 2023 |
A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides S Trabulo, S Resina, S Simões, B Lebleu, MCP de Lima Journal of controlled release 145 (2), 149-158, 2010 | 47 | 2010 |
S413‐PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA S Trabulo, M Mano, H Faneca, AL Cardoso, S Duarte, A Henriques, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2008 | 44 | 2008 |
Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus KM Moore, A Desai, B de Luxán Delgado, SMD Trabulo, C Reader, ... Theranostics 10 (7), 2930, 2020 | 42 | 2020 |
Drug delivery systems: advanced technologies potentially applicable in personalised treatment H Faneca, A Cardoso, S Trabulo, S Duarte, MCP de Lima Advances in Predictive, Preventive and Personalised Medicine 4, 153-184, 2013 | 40 | 2013 |
Multimodal treatment eliminates cancer stem cells and leads to long-term survival in primary human pancreatic cancer tissue xenografts PC Hermann, SM Trabulo, B Sainz Jr, A Balic, E Garcia, SA Hahn, ... PloS one 8 (6), e66371, 2013 | 39 | 2013 |