Protein kinase B (PKB/Akt)–a key regulator of glucose transport? E Hajduch, GJ Litherland, HS Hundal FEBS letters 492 (3), 199-203, 2001 | 397 | 2001 |
Cellular senescence in osteoarthritis pathology K McCulloch, GJ Litherland, TS Rai Aging cell 16 (2), 210-218, 2017 | 358 | 2017 |
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells E Hajduch, A Balendran, IH Batty, GJ Litherland, AS Blair, CP Downes, ... Diabetologia 44, 173-183, 2001 | 299 | 2001 |
Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases W Hui, GJ Litherland, MS Elias, GI Kitson, TE Cawston, AD Rowan, ... Annals of the rheumatic diseases 71 (3), 455-462, 2012 | 270 | 2012 |
Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress: evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated … AS Blair, E Hajduch, GJ Litherland, HS Hundal Journal of Biological Chemistry 274 (51), 36293-36299, 1999 | 205 | 1999 |
Key role for ceramides in mediating insulin resistance in human muscle cells L Pickersgill, GJ Litherland, AS Greenberg, M Walker, SJ Yeaman Journal of Biological Chemistry 282 (17), 12583-12589, 2007 | 199 | 2007 |
Differential Toll-like receptor-dependent collagenase expression in chondrocytes Q Zhang, W Hui, GJ Litherland, MJ Barter, R Davidson, C Darrah, ... Annals of the rheumatic diseases 67 (11), 1633-1641, 2008 | 116 | 2008 |
HDAC-mediated control of ERK-and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes MJ Barter, L Pybus, GJ Litherland, AD Rowan, IM Clark, DR Edwards, ... Matrix Biology 29 (7), 602-612, 2010 | 103 | 2010 |
Subcellular localization and adaptive up-regulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes R HYDE, GR CHRISTIE, GJ LITHERLAND, E HAJDUCH, PM TAYLOR, ... Biochemical Journal 355 (3), 563-568, 2001 | 101 | 2001 |
Metalloproteases as potential therapeutic targets in arthritis treatment AD Rowan, GJ Litherland, W Hui, JM Milner Expert opinion on therapeutic targets 12 (1), 1-18, 2008 | 89 | 2008 |
Fructose transport and metabolism in adipose tissue of Zucker rats: diminished GLUT5 activity during obesity and insulin resistance GJ Litherland, E Hajduch, GW Gould, HS Hundal Molecular and cellular biochemistry 261, 23-33, 2004 | 83 | 2004 |
Exosomes in intercellular communication and implications for osteoarthritis S Asghar, GJ Litherland, JC Lockhart, CS Goodyear, A Crilly Rheumatology 59 (1), 57-68, 2020 | 74 | 2020 |
A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B K Peyrollier, E Hajduch, A Gray, GJ Litherland, AR Prescott, NR Leslie, ... Biochemical Journal 352 (3), 617-622, 2000 | 74 | 2000 |
Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent GJ Litherland, C Dixon, RL Lakey, T Robson, D Jones, DA Young, ... Journal of Biological Chemistry 283 (21), 14221-14229, 2008 | 73 | 2008 |
The serpin superfamily and their role in the regulation and dysfunction of serine protease activity in COPD and other chronic lung diseases GA Kelly-Robinson, JA Reihill, FT Lundy, LP McGarvey, JC Lockhart, ... International journal of molecular sciences 22 (12), 6351, 2021 | 72 | 2021 |
Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family H Xie, SG Patching, MP Gallagher, GJ Litherland, AR Brough, H Venter, ... Molecular membrane biology 21 (5), 323-336, 2004 | 68 | 2004 |
Intracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues GJ Litherland, E Hajduch, HS Hundal Molecular membrane biology 18 (3), 195-204, 2001 | 67 | 2001 |
Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway W Hui, GJ Litherland, M Jefferson, MJ Barter, MS Elias, TE Cawston, ... Rheumatology 49 (11), 2043-2053, 2010 | 64 | 2010 |
Cytokine-induced MMP13 expression in human chondrocytes is dependent on activating transcription factor 3 (ATF3) regulation CM Chan, CD Macdonald, GJ Litherland, DJ Wilkinson, A Skelton, ... Journal of Biological Chemistry 292 (5), 1625-1636, 2017 | 61 | 2017 |
Protein kinase C isoforms ζ and ι mediate collagenase expression and cartilage destruction via STAT3-and ERK-dependent c-fos induction GJ Litherland, MS Elias, W Hui, CD Macdonald, JB Catterall, MJ Barter, ... Journal of Biological Chemistry 285 (29), 22414-22425, 2010 | 58 | 2010 |