| Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy CMG De Luca, AE Elia, SM Portaleone, FA Cazzaniga, M Rossi, E Bistaffa, ... Translational neurodegeneration 8, 1-14, 2019 | 169 | 2019 |
| TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients C Scialò, TH Tran, G Salzano, G Novi, C Caponnetto, A Chiò, A Calvo, ... Brain communications 2 (2), fcaa142, 2020 | 83 | 2020 |
| Structural consequences of copper binding to the prion protein G Salzano, G Giachin, G Legname Cells 8 (8), 770, 2019 | 63 | 2019 |
| Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia V Redaelli, E Bistaffa, G Zanusso, G Salzano, L Sacchetto, M Rossi, ... Scientific reports 7 (1), 46269, 2017 | 55 | 2017 |
| The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion G Giachin, PT Mai, TH Tran, G Salzano, F Benetti, V Migliorati, A Arcovito, ... Scientific reports 5 (1), 15253, 2015 | 48 | 2015 |
| The N terminus of the prion protein mediates functional interactions with the neuronal cell adhesion molecule (NCAM) fibronectin domain U Slapšak, G Salzano, L Amin, RNN Abskharon, G Ilc, B Zupančič, I Biljan, ... Journal of Biological Chemistry 291 (42), 21857-21868, 2016 | 44 | 2016 |
| A mechanistic review of Parkin activation M Gundogdu, R Tadayon, G Salzano, GS Shaw, H Walden Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (6), 129894, 2021 | 26 | 2021 |
| Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids E Bistaffa, TT Vuong, FA Cazzaniga, L Tran, G Salzano, G Legname, ... Scientific Reports 9 (1), 18595, 2019 | 24 | 2019 |
| Synthetic prions and other human neurodegenerative proteinopathies NTT Le, J Narkiewicz, S Aulić, G Salzano, HT Tran, D Scaini, F Moda, ... Virus research 207, 25-37, 2015 | 22 | 2015 |
| Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene G Di Fede, M Catania, C Atzori, F Moda, C Pasquali, A Indaco, M Grisoli, ... Acta Neuropathologica Communications 7, 1-11, 2019 | 16 | 2019 |
| Deciphering copper coordination in the mammalian prion protein amyloidogenic domain G Salzano, M Brennich, G Mancini, TH Tran, G Legname, P D’Angelo, ... Biophysical Journal 118 (3), 676-687, 2020 | 13 | 2020 |
| PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease FA Cazzaniga, E Bistaffa, CMG De Luca, SM Portaleone, M Catania, ... Frontiers in Aging Neuroscience 14, 848991, 2022 | 8 | 2022 |
| In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives L Zaccagnini, G Rossetti, TH Tran, G Salzano, A Gandini, AC Baldeschi, ... European journal of medicinal chemistry 196, 112295, 2020 | 8 | 2020 |
| Synthetic prion selection and adaptation E Bistaffa, F Moda, T Virgilio, I Campagnani, CMG De Luca, M Rossi, ... Molecular Neurobiology 56, 2978-2989, 2019 | 8 | 2019 |
| Unique structural features of mule deer prion protein provide insights into chronic wasting disease U Slapšak, G Salzano, G Ilc, G Giachin, J Bian, G Telling, G Legname, ... ACS omega 4 (22), 19913-19924, 2019 | 6 | 2019 |
| Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by parkin KM Dunkerley, AC Rintala-Dempsey, G Salzano, R Tadayon, D Hadi, ... Biochemical Journal 479 (6), 751-766, 2022 | 4 | 2022 |
| Structural and dynamical determinants of a β-sheet-enriched intermediate involved in amyloid fibrillar assembly of human prion protein L Russo, G Salzano, A Corvino, E Bistaffa, F Moda, L Celauro, ... Chemical Science 13 (35), 10406-10427, 2022 | 4 | 2022 |
| A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1 J Koszela, A Rintala-Dempsey, G Salzano, V Pimenta, O Kamarainen, ... bioRxiv, 2024 | 2 | 2024 |
| Synthetic mammalian prions F Moda, E Bistaffa, J Narkiewicz, G Salzano, G Legname Prion Diseases, 209-228, 2017 | 2 | 2017 |
| Unfolding Mechanism and Fibril Formation Propensity of Human Prion Protein in the Presence of Molecular Crowding Agents M Madheswaran, N Ventserova, G D’Abrosca, G Salzano, L Celauro, ... International Journal of Molecular Sciences 25 (18), 9916, 2024 | | 2024 |
Giuseppe LegnameProfessor of Biochemistry - SISSA - UCSF - NIMR/MRCEmail được xác minh tại sissa.it