Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers Y Lin, H Zhang, J Liang, K Li, W Zhu, L Fu, F Wang, X Zheng, H Shi, S Wu, ... Proceedings of the National Academy of Sciences 111 (42), E4504-E4512, 2014 | 158 | 2014 |
The anti-Warburg effect elicited by the cAMP-PGC1α pathway drives differentiation of glioblastoma cells into astrocytes F Xing, Y Luan, J Cai, S Wu, J Mai, J Gu, H Zhang, K Li, Y Lin, X Xiao, ... Cell reports 18 (2), 468-481, 2017 | 119 | 2017 |
Activation of cyclic AMP/PKA pathway inhibits bladder cancer cell invasion by targeting MAP4-dependent microtubule dynamics Y Ou, X Zheng, Y Gao, M Shu, T Leng, Y Li, W Yin, W Zhu, Y Huang, ... Urologic Oncology: Seminars and Original Investigations 32 (1), 47. e21-47. e28, 2014 | 75 | 2014 |
Targeting VCP enhances anticancer activity of oncolytic virus M1 in hepatocellular carcinoma H Zhang, K Li, Y Lin, F Xing, X Xiao, J Cai, W Zhu, J Liang, Y Tan, L Fu, ... Science translational medicine 9 (404), eaam7996, 2017 | 71 | 2017 |
Characterization of the Myocarditis during the worst outbreak of dengue infection in China Y Li, Z Hu, Y Huang, J Li, W Hong, Z Qin, Y Tong, J Li, M Lv, M Li, X Zheng, ... Medicine 95 (27), e4051, 2016 | 62 | 2016 |
Liposome encapsulation of oncolytic virus M1 to reduce immunogenicity and immune clearance in vivo Y Wang, H Huang, H Zou, X Tian, J Hu, P Qiu, H Hu, G Yan Molecular Pharmaceutics 16 (2), 779-785, 2019 | 51 | 2019 |
Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein J Hu, XF Cai, G Yan Cell cycle 8 (20), 3328-3339, 2009 | 51 | 2009 |
DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage X Xiao, J Liang, C Huang, K Li, F Xing, W Zhu, Z Lin, W Xu, G Wu, J Zhang, ... Nature Communications 9 (1), 4342, 2018 | 47 | 2018 |
Naturally existing oncolytic virus M1 is nonpathogenic for the nonhuman primates after multiple rounds of repeated intravenous injections H Zhang, Y Lin, K Li, J Liang, X Xiao, J Cai, Y Tan, F Xing, J Mai, Y Li, ... Human Gene Therapy 27 (9), 700-711, 2016 | 47 | 2016 |
Activation of cyclic adenosine monophosphate pathway increases the sensitivity of cancer cells to the oncolytic virus M1 K Li, H Zhang, J Qiu, Y Lin, J Liang, X Xiao, L Fu, F Wang, J Cai, Y Tan, ... Molecular Therapy 24 (1), 156-165, 2016 | 43 | 2016 |
Determining molecular predictors of adverse drug reactions with causality analysis based on structure learning M Liu, R Cai, Y Hu, ME Matheny, J Sun, J Hu, H Xu Journal of the American Medical Informatics Association 21 (2), 245-251, 2014 | 41 | 2014 |
Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC J Zhang, Y Liu, J Tan, Y Zhang, CW Wong, Z Lin, X Liu, M Sander, X Yang, ... Oncogene 40 (29), 4783-4795, 2021 | 35 | 2021 |
Triptolide inhibits proliferation and invasion of malignant glioma cells H Zhang, W Zhu, X Su, S Wu, Y Lin, J Li, Y Wang, J Chen, Y Zhou, P Qiu, ... Journal of neuro-oncology 109, 53-62, 2012 | 35 | 2012 |
Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells Y Zhou, S Wu, C Liang, Y Lin, Y Zou, K Li, B Lu, M Shu, Y Huang, W Zhu, ... Neuro-oncology 17 (12), 1578-1588, 2015 | 29 | 2015 |
Inhibition of the mevalonate pathway enhances cancer cell oncolysis mediated by M1 virus J Liang, L Guo, K Li, X Xiao, W Zhu, X Zheng, J Hu, H Zhang, J Cai, Y Yu, ... Nature Communications 9 (1), 1524, 2018 | 28 | 2018 |
Identification of the receptor of oncolytic virus M1 as a therapeutic predictor for multiple solid tumors D Song, X Jia, X Liu, L Hu, K Lin, T Xiao, Y Qiao, J Zhang, J Dan, C Wong, ... Signal transduction and targeted therapy 7 (1), 100, 2022 | 25 | 2022 |
Diazepam inhibits proliferation of human glioblastoma cells through triggering a G0/G1 cell cycle arrest J Chen, Y Ouyang, L Cao, W Zhu, Y Zhou, Y Zhou, H Zhang, X Yang, ... Journal of Neurosurgical Anesthesiology 25 (3), 285-291, 2013 | 25 | 2013 |
A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1 K Li, J Liang, Y Lin, H Zhang, X Xiao, Y Tan, J Cai, W Zhu, F Xing, J Hu, ... Oncotarget 7 (30), 48443, 2016 | 24 | 2016 |
Systematic characterization of the biodistribution of the oncolytic virus M1 J Cai, W Zhu, Y Lin, S Zhang, X Chen, S Gong, S He, J Hu, G Yan, J Liang Human Gene Therapy 31 (21-22), 1203-1213, 2020 | 21 | 2020 |
Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell X Liu, C Guo, T Leng, Z Fan, J Mai, J Chen, J Xu, Q Li, B Jiang, K Sai, ... Cell Death & Disease 14 (2), 142, 2023 | 19 | 2023 |