Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets MD Gearhart, CM Corcoran, JA Wamstad, VJ Bardwell Molecular and cellular biology 26 (18), 6880-6889, 2006 | 403 | 2006 |
EZH2 and BCL6 cooperate to assemble CBX8-BCOR complex to repress bivalent promoters, mediate germinal center formation and lymphomagenesis W Béguelin, M Teater, MD Gearhart, MTC Fernández, RL Goldstein, ... Cancer cell 30 (2), 197-213, 2016 | 257 | 2016 |
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes SH Choi, MD Gearhart, Z Cui, D Bosnakovski, M Kim, N Schennum, ... Nucleic acids research 44 (11), 5161-5173, 2016 | 204 | 2016 |
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ... Cell reports 4 (3), 578-588, 2013 | 199 | 2013 |
Sexual cell-fate reprogramming in the ovary by DMRT1 RE Lindeman, MD Gearhart, A Minkina, AD Krentz, VJ Bardwell, ... Current Biology 25 (6), 764-771, 2015 | 155 | 2015 |
Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition MD Gearhart, SMA Holmbeck, RM Evans, HJ Dyson, PE Wright Journal of molecular biology 327 (4), 819-832, 2003 | 129 | 2003 |
An ancient protein-DNA interaction underlying metazoan sex determination MW Murphy, JK Lee, S Rojo, MD Gearhart, K Kurahashi, S Banerjee, ... Nature structural & molecular biology 22 (6), 442-451, 2015 | 126 | 2015 |
Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs SE Junco, R Wang, JC Gaipa, AB Taylor, V Schirf, MD Gearhart, ... Structure 21 (4), 665-671, 2013 | 114 | 2013 |
A non-canonical BCOR-PRC1. 1 complex represses differentiation programs in human ESCs Z Wang, MD Gearhart, YW Lee, I Kumar, B Ramazanov, Y Zhang, ... Cell stem cell 22 (2), 235-251. e9, 2018 | 94 | 2018 |
BCOR regulates myeloid cell proliferation and differentiation Q Cao, MD Gearhart, S Gery, S Shojaee, H Yang, H Sun, DC Lin, JW Bai, ... Leukemia 30 (5), 1155-1165, 2016 | 91 | 2016 |
The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis T Zhang, MW Murphy, MD Gearhart, VJ Bardwell, D Zarkower Development 141 (19), 3662-3671, 2014 | 84 | 2014 |
KDM2B recruitment of the polycomb group complex, PRC1. 1, requires cooperation between PCGF1 and BCORL1 SJ Wong, MD Gearhart, AB Taylor, DR Nanyes, DJ Ha, AK Robinson, ... Structure 24 (10), 1795-1801, 2016 | 67 | 2016 |
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis MJ Kelly, J So, AJ Rogers, G Gregory, J Li, M Zethoven, MD Gearhart, ... Nature communications 10 (1), 1347, 2019 | 66 | 2019 |
LIN-41 and OMA ribonucleoprotein complexes mediate a translational repression-to-activation switch controlling oocyte meiotic maturation and the oocyte-to-embryo transition in … T Tsukamoto, MD Gearhart, CA Spike, G Huelgas-Morales, M Mews, ... Genetics 206 (4), 2007-2039, 2017 | 62 | 2017 |
AP-1cFos/JunB/miR-200a regulate the pro-regenerative glial cell response during axolotl spinal cord regeneration KZ Sabin, P Jiang, MD Gearhart, R Stewart, K Echeverri Communications biology 2 (1), 91, 2019 | 54 | 2019 |
Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene M Lefebure, RW Tothill, E Kruse, ED Hawkins, J Shortt, GM Matthews, ... Nature communications 8 (1), 14581, 2017 | 50 | 2017 |
Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression D Bosnakovski, MD Gearhart, EA Toso, ET Ener, SH Choi, M Kyba Scientific reports 8 (1), 16957, 2018 | 48 | 2018 |
Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor α with minor groove binding polyamides MD Gearhart, L Dickinson, J Ehley, C Melander, PB Dervan, PE Wright, ... Biochemistry 44 (11), 4196-4203, 2005 | 48 | 2005 |
The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming RE Lindeman, MW Murphy, KS Agrimson, RL Gewiss, VJ Bardwell, ... Nucleic acids research 49 (11), 6144-6164, 2021 | 47 | 2021 |
Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary A Minkina, RE Lindeman, MD Gearhart, AA Chassot, MC Chaboissier, ... Developmental biology 424 (2), 208-220, 2017 | 42 | 2017 |