| STING is a direct innate immune sensor of cyclic di-GMP DL Burdette, KM Monroe, K Sotelo-Troha, JS Iwig, B Eckert, M Hyodo, ... Nature 478 (7370), 515-518, 2011 | 1708 | 2011 |
| Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection G Doitsh, NLK Galloway, X Geng, Z Yang, KM Monroe, O Zepeda, ... Nature 505 (7484), 509-514, 2014 | 1453 | 2014 |
| The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING EJ Diner, DL Burdette, SC Wilson, KM Monroe, CA Kellenberger, ... Cell reports 3 (5), 1355-1361, 2013 | 846 | 2013 |
| The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic … JD Sauer, K Sotelo-Troha, J Von Moltke, KM Monroe, CS Rae, ... Infection and immunity 79 (2), 688-694, 2011 | 658 | 2011 |
| IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV KM Monroe, Z Yang, JR Johnson, X Geng, G Doitsh, NJ Krogan, ... Science 343 (6169), 428-432, 2014 | 609 | 2014 |
| TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge AA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ... Neuron 105 (5), 837-854. e9, 2020 | 521 | 2020 |
| NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways IC Allen, CB Moore, M Schneider, Y Lei, BK Davis, MA Scull, D Gris, ... Immunity 34 (6), 854-865, 2011 | 413 | 2011 |
| A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP SM McWhirter, R Barbalat, KM Monroe, MF Fontana, M Hyodo, ... Journal of Experimental Medicine 206 (9), 1899-1911, 2009 | 366 | 2009 |
| Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region K Schlepckow, KM Monroe, G Kleinberger, L Cantuti‐Castelvetri, ... EMBO molecular medicine 12 (4), e11227, 2020 | 244 | 2020 |
| Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila KM Monroe, SM McWhirter, RE Vance PLoS pathogens 5 (11), e1000665, 2009 | 223 | 2009 |
| Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia BJ Andreone, L Przybyla, C Llapashtica, A Rana, SS Davis, ... Nature neuroscience 23 (8), 927-938, 2020 | 203 | 2020 |
| Emerging microglia biology defines novel therapeutic approaches for Alzheimer’s disease JW Lewcock, K Schlepckow, G Di Paolo, S Tahirovic, KM Monroe, ... Neuron 108 (5), 801-821, 2020 | 202 | 2020 |
| Induction of type I interferons by bacteria KM Monroe, SM McWhirter, RE Vance Cellular microbiology 12 (7), 881-890, 2010 | 200 | 2010 |
| Cell-to-cell transmission of HIV-1 is required to trigger pyroptotic death of lymphoid-tissue-derived CD4 T cells NLK Galloway, G Doitsh, KM Monroe, Z Yang, I Muñoz-Arias, DN Levy, ... Cell reports 12 (10), 1555-1563, 2015 | 181 | 2015 |
| Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava, SS Davis, RLY Low, ... Cell 184 (18), 4651-4668. e25, 2021 | 161 | 2021 |
| A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models B van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ... Nature neuroscience 26 (3), 416-429, 2023 | 158 | 2023 |
| Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination M Bosch-Queralt, L Cantuti-Castelvetri, A Damkou, M Schifferer, ... Nature metabolism 3 (2), 211-227, 2021 | 65 | 2021 |
| Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency A Reifschneider, S Robinson, B van Lengerich, J Gnörich, T Logan, ... The EMBO Journal 41 (4), e109108, 2022 | 55 | 2022 |
| Mummy, A UDP-N-acetylglucosamine pyrophosphorylase, modulates DPP signaling in the embryonic epidermis of Drosophila GB Humphreys, MC Jud, KM Monroe, SS Kimball, M Higley, D Shipley, ... Developmental biology 381 (2), 434-445, 2013 | 29 | 2013 |
| Correction: Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection G Doitsh, NLK Galloway, X Geng, Z Yang, KM Monroe, O Zepeda, ... Nature 544 (7648), 124-124, 2017 | 17 | 2017 |
