Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells G Gallina, L Dolcetti, P Serafini, C De Santo, I Marigo, MP Colombo, ... The Journal of clinical investigation 116 (10), 2777-2790, 2006 | 1001 | 2006 |
Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression P Serafini, I Borrello, V Bronte Seminars in cancer biology 16 (1), 53-65, 2006 | 974 | 2006 |
Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function P Serafini, K Meckel, M Kelso, K Noonan, J Califano, W Koch, L Dolcetti, ... Journal of Experimental Medicine 203 (12), 2691-2702, 2006 | 895 | 2006 |
Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells P Serafini, S Mgebroff, K Noonan, I Borrello Cancer research 68 (13), 5439-5449, 2008 | 864 | 2008 |
Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism A Mazzoni, V Bronte, A Visintin, JH Spitzer, E Apolloni, P Serafini, ... The Journal of Immunology 168 (2), 689-695, 2002 | 849 | 2002 |
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells I Marigo, L Dolcetti, P Serafini, P Zanovello, V Bronte Immunological reviews 222 (1), 162-179, 2008 | 795 | 2008 |
L-arginine metabolism in myeloid cells controls T-lymphocyte functions V Bronte, P Serafini, A Mazzoni, DM Segal, P Zanovello Trends in immunology 24 (6), 301-305, 2003 | 750 | 2003 |
Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+T cells V Bronte, E Apolloni, A Cabrelle, R Ronca, P Serafini, P Zamboni, ... Blood, The Journal of the American Society of Hematology 96 (12), 3838-3846, 2000 | 690 | 2000 |
IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice V Bronte, P Serafini, C De Santo, I Marigo, V Tosello, A Mazzoni, ... The Journal of Immunology 170 (1), 270-278, 2003 | 655 | 2003 |
High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells P Serafini, R Carbley, KA Noonan, G Tan, V Bronte, I Borrello Cancer research 64 (17), 6337-6343, 2004 | 644 | 2004 |
Derangement of immune responses by myeloid suppressor cells P Serafini, C De Santo, I Marigo, S Cingarlini, L Dolcetti, G Gallina, ... Cancer Immunology, Immunotherapy 53, 64-72, 2004 | 437 | 2004 |
Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination C De Santo, P Serafini, I Marigo, L Dolcetti, M Bolla, P Del Soldato, ... Proceedings of the National Academy of Sciences 102 (11), 4185-4190, 2005 | 371 | 2005 |
Tumor-induced immune dysfunctions caused by myeloid suppressor cells V Bronte, P Serafini, E Apolloni, P Zanovello Journal of immunotherapy 24 (6), 431-446, 2001 | 292 | 2001 |
Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma DT Weed, JL Vella, IM Reis, AC De la Fuente, C Gomez, Z Sargi, ... Clinical cancer research 21 (1), 39-48, 2015 | 271 | 2015 |
Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression F Roth, AC De La Fuente, JL Vella, A Zoso, L Inverardi, P Serafini Cancer research 72 (6), 1373-1383, 2012 | 209 | 2012 |
Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma JA Califano, Z Khan, KA Noonan, L Rudraraju, Z Zhang, H Wang, ... Clinical cancer research 21 (1), 30-38, 2015 | 200 | 2015 |
Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes E Apolloni, V Bronte, A Mazzoni, P Serafini, A Cabrelle, DM Segal, ... The Journal of Immunology 165 (12), 6723-6730, 2000 | 197 | 2000 |
Human fibrocytic myeloid‐derived suppressor cells express IDO and promote tolerance via Treg‐cell expansion A Zoso, EMC Mazza, S Bicciato, S Mandruzzato, V Bronte, P Serafini, ... European journal of immunology 44 (11), 3307-3319, 2014 | 146 | 2014 |
Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors K Noonan, W Matsui, P Serafini, R Carbley, G Tan, J Khalili, M Bonyhadi, ... Cancer research 65 (5), 2026-2034, 2005 | 142 | 2005 |
Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells P Daftarian, AE Kaifer, W Li, BB Blomberg, D Frasca, F Roth, ... Cancer research 71 (24), 7452-7462, 2011 | 128 | 2011 |