| Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle C Yu, Y Chen, GW Cline, D Zhang, H Zong, Y Wang, R Bergeron, JK Kim, ... Journal of Biological Chemistry 277 (52), 50230-50236, 2002 | 1974 | 2002 |
| Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. ME Griffin, MJ Marcucci, GW Cline, K Bell, N Barucci, D Lee, LJ Goodyear, ... Diabetes 48 (6), 1270-1274, 1999 | 1734 | 1999 |
| Influence of dietary fat composition on development of insulin resistance in rats: relationship to muscle triglyceride and ω-3 fatty acids in muscle phospholipid LH Storlien, AB Jenkins, DJ Chisholm, WS Pascoe, S Khouri, ... Diabetes 40 (2), 280-289, 1991 | 1388 | 1991 |
| Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states YS Lee, WS Kim, KH Kim, MJ Yoon, HJ Cho, Y Shen, JM Ye, CH Lee, ... Diabetes 55 (8), 2256-2264, 2006 | 1379 | 2006 |
| Fish oil prevents insulin resistance induced by high-fat feeding in rats LH Storlien, EW Kraegen, DJ Chisholm, GL Ford, DG Bruce, WS Pascoe Science 237 (4817), 885-888, 1987 | 894 | 1987 |
| Development of muscle insulin resistance after liver insulin resistance in high-fat–fed rats EW Kraegen, PW Clark, AB Jenkins, EA Daley, DJ Chisholm, LH Storlien Diabetes 40 (11), 1397-1403, 1991 | 845 | 1991 |
| Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats LH Storlien, DE James, KM Burleigh, DJ Chisholm, EW Kraegen American Journal of Physiology-Endocrinology and Metabolism 251 (5), E576-E583, 1986 | 772 | 1986 |
| Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans Y Wang, KSL Lam, EW Kraegen, G Sweeney, J Zhang, AWK Tso, ... Clinical chemistry 53 (1), 34-41, 2007 | 755 | 2007 |
| Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP … N Turner, JY Li, A Gosby, SWC To, Z Cheng, H Miyoshi, MM Taketo, ... Diabetes 57 (5), 1414-1418, 2008 | 629 | 2008 |
| Insulin resistance is a cellular antioxidant defense mechanism KL Hoehn, AB Salmon, C Hohnen-Behrens, N Turner, AJ Hoy, ... Proceedings of the National Academy of Sciences 106 (42), 17787-17792, 2009 | 622 | 2009 |
| Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding ND Oakes, GJ Cooney, S Camilleri, DJ Chisholm, EW Kraegen Diabetes 46 (11), 1768-1774, 1997 | 583 | 1997 |
| Dose-response curves for in vivo insulin sensitivity in individual tissues in rats EW Kraegen, DE James, AB Jenkins, DJ Chisholm American Journal of Physiology-Endocrinology and Metabolism 248 (3), E353-E362, 1985 | 581 | 1985 |
| Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats AW Thorburn, LH Storlien, AB Jenkins, S Khouri, EW Kraegen The American Journal of Clinical Nutrition 49 (6), 1155-1163, 1989 | 500 | 1989 |
| Heterogeneity of insulin action in individual muscles in vivo: euglycemic clamp studies in rats DE James, AB Jenkins, EW Kraegen American Journal of Physiology-Endocrinology and Metabolism 248 (5), E567-E574, 1985 | 499 | 1985 |
| Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding N Turner, GM Kowalski, SJ Leslie, S Risis, C Yang, RS Lee-Young, ... Diabetologia 56, 1638-1648, 2013 | 488 | 2013 |
| Peroxisome Proliferator—Activated Receptor (PPAR)-αActivation Lowers Muscle Lipids and Improves Insulin Sensitivity in High Fat—Fed Rats: Comparison With PPAR-γ Activation JM Ye, PJ Doyle, MA Iglesias, DG Watson, GJ Cooney, EW Kraegen Diabetes 50 (2), 411-417, 2001 | 480 | 2001 |
| Apparatus for improving blood sugar control in diabetics EW Kraegen, L Lazarus, DJ Bell, DJ Chisholm US Patent 4,475,901, 1984 | 460 | 1984 |
| Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet–induced insulin resistance CR Bruce, AJ Hoy, N Turner, MJ Watt, TL Allen, K Carpenter, GJ Cooney, ... Diabetes 58 (3), 550-558, 2009 | 447 | 2009 |
| Alterations in the expression and cellular localization of protein kinase C isozymes ε and θ are associated with insulin resistance in skeletal muscle of the high-fat–fed rat C Schmitz-Peiffer, CL Browne, ND Oakes, A Watkinson, DJ Chisholm, ... Diabetes 46 (2), 169-178, 1997 | 436 | 1997 |
| Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes DG Bruce, DJ Chisholm, LH Storlien, EW Kraegen Diabetes 37 (6), 736-744, 1988 | 407 | 1988 |
