An integrative genomics approach to infer causal associations between gene expression and disease EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ... Nature genetics 37 (7), 710-717, 2005 | 1249 | 2005 |
Variations in DNA elucidate molecular networks that cause disease Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ... Nature 452 (7186), 429-435, 2008 | 1088 | 2008 |
EUROCARE-3 summary: cancer survival in Europe at the end of the 20th century MP Coleman, G Gatta, A Verdecchia, J Esteve, M Sant, H Storm, ... Annals of oncology 14, v128-v149, 2003 | 703 | 2003 |
Experimental annotation of the human genome using microarray technology DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ... Nature 409 (6822), 922-927, 2001 | 619 | 2001 |
Genetic inheritance of gene expression in human cell lines SA Monks, A Leonardson, H Zhu, P Cundiff, P Pietrusiak, S Edwards, ... The American Journal of Human Genetics 75 (6), 1094-1105, 2004 | 478 | 2004 |
Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments JM Johnson, S Edwards, D Shoemaker, EE Schadt TRENDS in Genetics 21 (2), 93-102, 2005 | 462 | 2005 |
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility MP Keller, YJ Choi, P Wang, DB Davis, ME Rabaglia, AT Oler, ... Genome research 18 (5), 706-716, 2008 | 405 | 2008 |
Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA) KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ... Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014 | 373 | 2014 |
Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action GT Ankley, DC Bencic, MS Breen, TW Collette, RB Conolly, ND Denslow, ... Aquatic toxicology 92 (3), 168-178, 2009 | 325 | 2009 |
An integrative genomics approach to the reconstruction of gene networks in segregating populations J Zhu, PY Lum, J Lamb, D GuhaThakurta, SW Edwards, R Thieringer, ... Cytogenetic and genome research 105 (2-4), 363-374, 2004 | 294 | 2004 |
Increasing scientific confidence in adverse outcome pathways: application of tailored Bradford-Hill considerations for evaluating weight of evidence RA Becker, GT Ankley, SW Edwards, SW Kennedy, I Linkov, B Meek, ... Regulatory Toxicology and Pharmacology 72 (3), 514-537, 2015 | 272 | 2015 |
Genes, themes and microarrays H Shatkay, S Edwards, WJ Wilbur, M Boguski Proc. Int. Conf. Intell. Syst. Mol. Biol 8, 317-327, 2000 | 246 | 2000 |
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits M Mehrabian, H Allayee, J Stockton, PY Lum, TA Drake, LW Castellani, ... Nature genetics 37 (11), 1224-1233, 2005 | 243 | 2005 |
Synthesis of redox derivatives of lysine and related peptides containing phenothiazine or tris (2, 2′‐bipyridine) ruthenium (II) BM PEEK, GT ROSS, SW EDWARDS, GJ MEYER, TJ MEYER, ... International journal of peptide and protein research 38 (2), 114-123, 1991 | 217 | 1991 |
Adverse outcome pathways—organizing toxicological information to improve decision making SW Edwards, YM Tan, DL Villeneuve, ME Meek, CA McQueen The Journal of pharmacology and experimental therapeutics 356 (1), 170-181, 2016 | 207 | 2016 |
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels AC Cervino, G Li, S Edwards, J Zhu, C Laurie, G Tokiwa, PY Lum, S Wang, ... Genomics 86 (5), 505-517, 2005 | 162 | 2005 |
A comprehensive transcript index of the human genome generated using microarrays and computational approaches EE Schadt, SW Edwards, D GuhaThakurta, D Holder, L Ying, V Svetnik, ... Genome biology 5, 1-17, 2004 | 152 | 2004 |
Completing the link between exposure science and toxicology for improved environmental health decision making: the aggregate exposure pathway framework JG Teeguarden, YM Tan, SW Edwards, JA Leonard, KA Anderson, ... Environmental Science & Technology 50 (9), 4579-4586, 2016 | 140 | 2016 |
Systems biology and mode of action based risk assessment SW Edwards, RJ Preston Toxicological Sciences 106 (2), 312-318, 2008 | 128 | 2008 |
The adverse outcome pathway: a multifaceted framework supporting 21st century toxicology GT Ankley, SW Edwards Current opinion in toxicology 9, 1-7, 2018 | 127 | 2018 |