Theo dõi
Leena Gandhi
Leena Gandhi
Chief Medical Officer, NextPoint Therapeutics
Email được xác minh tại nextpointtx.com
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Pembrolizumab for the treatment of non–small-cell lung cancer
EB Garon, NA Rizvi, R Hui, N Leighl, AS Balmanoukian, JP Eder, ...
New England Journal of Medicine 372 (21), 2018-2028, 2015
68472015
Pembrolizumab plus chemotherapy in metastatic non–small-cell lung cancer
L Gandhi, D Rodríguez-Abreu, S Gadgeel, E Esteban, E Felip, ...
New England journal of medicine 378 (22), 2078-2092, 2018
63352018
Anaplastic lymphoma kinase inhibition in non–small-cell lung cancer
EL Kwak, YJ Bang, DR Camidge, AT Shaw, B Solomon, RG Maki, SHI Ou, ...
New England Journal of Medicine 363 (18), 1693-1703, 2010
55422010
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study
DR Camidge, YJ Bang, EL Kwak, AJ Iafrate, M Varella-Garcia, SB Fox, ...
The lancet oncology 13 (10), 1011-1019, 2012
15792012
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
S Koyama, EA Akbay, YY Li, GS Herter-Sprie, KA Buczkowski, ...
Nature communications 7 (1), 10501, 2016
15362016
Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study
CJ Langer, SM Gadgeel, H Borghaei, VA Papadimitrakopoulou, A Patnaik, ...
The lancet oncology 17 (11), 1497-1508, 2016
15302016
Overall survival and long-term safety of nivolumab (anti–programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non–small-cell lung cancer
SN Gettinger, L Horn, L Gandhi, DR Spigel, SJ Antonia, NA Rizvi, ...
Journal of clinical oncology 33 (18), 2004-2012, 2015
13332015
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
Z Sun, CW Arendt, W Ellmeier, EM Schaeffer, MJ Sunshine, L Gandhi, ...
Nature 404 (6776), 402-407, 2000
11442000
PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib
JA Engelman, K Zejnullahu, CM Gale, E Lifshits, AJ Gonzales, ...
Cancer research 67 (24), 11924-11932, 2007
8532007
Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG …
SM Gadgeel, L Gandhi, GJ Riely, AA Chiappori, HL West, MC Azada, ...
The Lancet Oncology 15 (10), 1119-1128, 2014
8112014
Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (6), 311-335, 2017
8002017
Efficacy and safety of abemaciclib, an inhibitor of CDK4 and CDK6, for patients with breast cancer, non–small cell lung cancer, and other solid tumors
A Patnaik, LS Rosen, SM Tolaney, AW Tolcher, JW Goldman, L Gandhi, ...
Cancer discovery 6 (7), 740-753, 2016
7292016
Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial
AT Shaw, L Gandhi, S Gadgeel, GJ Riely, J Cetnar, H West, DR Camidge, ...
The lancet oncology 17 (2), 234-242, 2016
7202016
Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the international immunooncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (5), 235-251, 2017
7032017
Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors
L Gandhi, DR Camidge, M Ribeiro de Oliveira, P Bonomi, D Gandara, ...
Journal of clinical oncology 29 (7), 909-916, 2011
6852011
Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer
CM Rudin, CL Hann, EB Garon, M Ribeiro de Oliveira, PD Bonomi, ...
Clinical Cancer Research 18 (11), 3163-3169, 2012
6522012
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
EM Van Allen, N Wagle, P Stojanov, DL Perrin, K Cibulskis, S Marlow, ...
Nature medicine 20 (6), 682-688, 2014
5862014
Small cell lung cancer
GP Kalemkerian, W Akerley, P Bogner, H Borghaei, LQM Chow, ...
Journal of the National Comprehensive Cancer Network 11 (1), 78-98, 2013
4912013
Bias-corrected targeted next-generation sequencing for rapid, multiplexed detection of actionable alterations in cell-free DNA from advanced lung cancer patients
CP Paweletz, AG Sacher, CK Raymond, RS Alden, A O'Connell, SL Mach, ...
Clinical Cancer Research 22 (4), 915-922, 2016
3222016
Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib
N Wagle, BC Grabiner, EM Van Allen, E Hodis, S Jacobus, JG Supko, ...
Cancer discovery 4 (5), 546-553, 2014
3072014
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