Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery L Tang, Y Zheng, MB Melo, L Mabardi, AP Castaño, YQ Xie, N Li, ... Nature biotechnology 36 (8), 707-716, 2018 | 591 | 2018 |
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination HH Tam, MB Melo, M Kang, JM Pelet, VM Ruda, MH Foley, JK Hu, ... Proceedings of the National Academy of Sciences 113 (43), E6639-E6648, 2016 | 426 | 2016 |
Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants MC Hanson, MP Crespo, W Abraham, KD Moynihan, GL Szeto, SH Chen, ... The Journal of clinical investigation 125 (6), 2532-2546, 2015 | 391 | 2015 |
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ... Cell 177 (5), 1153-1171. e28, 2019 | 372 | 2019 |
Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice WA Andrade, M do Carmo Souza, E Ramos-Martinez, K Nagpal, ... Cell host & microbe 13 (1), 42-53, 2013 | 261 | 2013 |
The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response W Niedelman, DA Gold, EE Rosowski, JK Sprokholt, D Lim, ... PLoS pathogens 8 (6), e1002784, 2012 | 251 | 2012 |
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii G Gorfu, KM Cirelli, MB Melo, K Mayer-Barber, D Crown, BH Koller, ... MBio 5 (1), 10.1128/mbio. 01117-13, 2014 | 245 | 2014 |
The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease C Junqueira, B Caetano, DC Bartholomeu, MB Melo, C Ropert, ... Expert reviews in molecular medicine 12, e29, 2010 | 245 | 2010 |
Toxoplasma gondii effectors are master regulators of the inflammatory response MB Melo, KDC Jensen, JPJ Saeij Trends in parasitology 27 (11), 487-495, 2011 | 243 | 2011 |
Engineered immunogen binding to alum adjuvant enhances humoral immunity TJ Moyer, Y Kato, W Abraham, JYH Chang, DW Kulp, N Watson, ... Nature medicine 26 (3), 430-440, 2020 | 242 | 2020 |
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity EL Dane, A Belessiotis-Richards, C Backlund, J Wang, K Hidaka, ... Nature Materials 21 (6), 710-720, 2022 | 205 | 2022 |
Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity S Minot, MB Melo, F Li, D Lu, W Niedelman, SS Levine, JPJ Saeij Proceedings of the National Academy of Sciences 109 (33), 13458-13463, 2012 | 121 | 2012 |
Transcriptional analysis of murine macrophages infected with different Toxoplasma strains identifies novel regulation of host signaling pathways MB Melo, QP Nguyen, C Cordeiro, MA Hassan, N Yang, R McKell, ... PLoS Pathog 9 (12), e1003779, 2013 | 110 | 2013 |
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity Y Agarwal, LE Milling, JYH Chang, L Santollani, A Sheen, EA Lutz, ... Nature biomedical engineering 6 (2), 129-143, 2022 | 109 | 2022 |
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity M Silva, Y Kato, MB Melo, I Phung, BL Freeman, Z Li, K Roh, ... Science immunology 6 (66), eabf1152, 2021 | 103 | 2021 |
Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi BC Caetano, BB Carmo, MB Melo, A Cerny, SL dos Santos, ... The Journal of Immunology 187 (4), 1903-1911, 2011 | 99 | 2011 |
Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination KDC Jensen, A Camejo, MB Melo, C Cordeiro, L Julien, GM Grotenbreg, ... MBio 6 (2), 10.1128/mbio. 02280-14, 2015 | 95 | 2015 |
Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles YSS Yang, KD Moynihan, A Bekdemir, TM Dichwalkar, MM Noh, ... Biomaterials science 7 (1), 113-124, 2019 | 89 | 2019 |
Enhancing humoral responses against HIV envelope trimers via nanoparticle delivery with stabilized synthetic liposomes T Tokatlian, DW Kulp, AA Mutafyan, CA Jones, S Menis, E Georgeson, ... Scientific Reports 8 (1), 16527, 2018 | 89 | 2018 |
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi DC Bartholomeu, C Ropert, MB Melo, P Parroche, CF Junqueira, ... The Journal of Immunology 181 (2), 1333-1344, 2008 | 88 | 2008 |