Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications N Brodyagin, M Katkevics, V Kotikam, CA Ryan, E Rozners Beilstein journal of organic chemistry 17 (1), 1641-1688, 2021 | 59 | 2021 |
Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids V Kotikam, SD Kennedy, JA MacKay, E Rozners Chemistry–A European Journal 25 (17), 4367-4372, 2019 | 43 | 2019 |
A single amide linkage in the passenger strand suppresses its activity and enhances guide strand targeting of siRNAs T Hardcastle, I Novosjolova, V Kotikam, SK Cheruiyot, D Mutisya, ... ACS chemical biology 13 (3), 533-536, 2018 | 33 | 2018 |
Amide-modified RNA: using protein backbone to modulate function of short interfering RNAs V Kotikam, E Rozners Accounts of chemical research 53 (9), 1782-1790, 2020 | 32 | 2020 |
Comparing the interactions of DNA, polyamide (PNA) and polycarbamate nucleic acid (PCNA) oligomers with graphene oxide (GO) V Kotikam, M Fernandes, VA Kumar Physical Chemistry Chemical Physics 14 (43), 15003-15006, 2012 | 30 | 2012 |
Synthesis and biological activity of short interfering RNAs having several consecutive amide internucleoside linkages V Kotikam, JA Viel, E Rozners Chemistry–A European Journal 26 (3), 685-690, 2020 | 16 | 2020 |
Concurrent hydrogenation of three functional groups enables synthesis of C3′-homologated nucleoside amino acids V Kotikam, E Rozners Organic letters 19 (15), 4122-4125, 2017 | 16 | 2017 |
Inhibition of miR-21 by 3′/5′-Serinyl-Capped 2′-O-Methyl RNA Interspersed with 2′-O-(2-Amino-3-Methoxypropyl) Uridine Units S Nahar, V Kotikam, VA Kumar, S Maiti nucleic acid therapeutics 26 (5), 327-334, 2016 | 12 | 2016 |
Amide internucleoside linkages are well tolerated in protospacer adjacent motif-distal region of CRISPR RNAs V Kotikam, PK Gajula, L Coyle, E Rozners ACS chemical biology 17 (3), 509-512, 2022 | 10 | 2022 |
Amide modifications in the seed region of the guide strand improve the on-target specificity of short interfering RNA M Richter, JA Viel, V Kotikam, PK Gajula, L Coyle, C Pal, E Rozners ACS chemical biology 18 (1), 7-11, 2022 | 9 | 2022 |
Synthesis and properties of 2′-O-[R-and S-(2-amino-3-methoxy) propyl](R-AMP and S-AMP) nucleic acids V Kotikam, VA Kumar Tetrahedron 69 (31), 6404-6408, 2013 | 9 | 2013 |
Enzymatic beacons for specific sensing of dilute nucleic acid X Zhang, V Kotikam, E Rozners, BP Callahan ChemBioChem 23 (4), e202100594, 2022 | 6 | 2022 |
Enhanced splice correction by 3′, 5′-serinol and 2′-(ω-O-methylserinol) guarded OMe-RNA/DNA mixmers in cells V Kotikam, AA Arzumanov, MJ Gait, VA Kumar Artificial DNA: PNA & XNA 4 (3), 77-83, 2013 | 5 | 2013 |
Locked and unlocked 2'-o phosphoramidite nucleosides, process of preparation thereof and oligomers comprising the nucleosides AK Vaijayanti, AD Gunjai, M D'costa, ND Erande, V Kotikam US Patent App. 12/876,494, 2011 | 4 | 2011 |
Robust synthesis of enantiopure cyclohexenyl analogues of 2/3-deoxyribose sugars as carbocyclic nucleoside precursors M Varada, V Kotikam, VA Kumar Tetrahedron 67 (32), 5744-5749, 2011 | 3 | 2011 |
Inhibition of miR-21 by 3 [variant prime]/5 [variant prime]-Serinyl-Capped 2 [variant prime]-O-Methyl RNA Interspersed with 2 [variant prime]-O-(2-Amino-3-Methoxypropyl … S Nahar, V Kotikam, VA Kumar, S Maiti Nucleic Acid Therapeutics 26 (5), 327, 2016 | 1 | 2016 |
Enzymatic Beacons for Specific Sensing of Dilute Nucleic Acid and Potential Utility for SARS-CoV-2 Detection X Zhang, V Kotikam, E Rozners, BP Callahan bioRxiv, 2021 | | 2021 |
2′/3′/5′-(R/S)-serinyl functionalized oligonucleotides VA Kumar, V Kotikam, S Maiti, S Nahar US Patent 9,920,319, 2018 | | 2018 |
Synthesis and evaluation of designed (S)-polycarbamate nucleic acids, erythrulose-based-and 2'-functionalized-oligonucleotide analogs for RNA targeting V Kotikam CSIR-National Chemical Laboratory, Pune, 2013 | | 2013 |