Theo dõi
Venubabu Kotikam
Venubabu Kotikam
Senior Scientist
Email được xác minh tại primemedicine.com
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications
N Brodyagin, M Katkevics, V Kotikam, CA Ryan, E Rozners
Beilstein journal of organic chemistry 17 (1), 1641-1688, 2021
592021
Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids
V Kotikam, SD Kennedy, JA MacKay, E Rozners
Chemistry–A European Journal 25 (17), 4367-4372, 2019
432019
A single amide linkage in the passenger strand suppresses its activity and enhances guide strand targeting of siRNAs
T Hardcastle, I Novosjolova, V Kotikam, SK Cheruiyot, D Mutisya, ...
ACS chemical biology 13 (3), 533-536, 2018
332018
Amide-modified RNA: using protein backbone to modulate function of short interfering RNAs
V Kotikam, E Rozners
Accounts of chemical research 53 (9), 1782-1790, 2020
322020
Comparing the interactions of DNA, polyamide (PNA) and polycarbamate nucleic acid (PCNA) oligomers with graphene oxide (GO)
V Kotikam, M Fernandes, VA Kumar
Physical Chemistry Chemical Physics 14 (43), 15003-15006, 2012
302012
Synthesis and biological activity of short interfering RNAs having several consecutive amide internucleoside linkages
V Kotikam, JA Viel, E Rozners
Chemistry–A European Journal 26 (3), 685-690, 2020
162020
Concurrent hydrogenation of three functional groups enables synthesis of C3′-homologated nucleoside amino acids
V Kotikam, E Rozners
Organic letters 19 (15), 4122-4125, 2017
162017
Inhibition of miR-21 by 3′/5′-Serinyl-Capped 2′-O-Methyl RNA Interspersed with 2′-O-(2-Amino-3-Methoxypropyl) Uridine Units
S Nahar, V Kotikam, VA Kumar, S Maiti
nucleic acid therapeutics 26 (5), 327-334, 2016
122016
Amide internucleoside linkages are well tolerated in protospacer adjacent motif-distal region of CRISPR RNAs
V Kotikam, PK Gajula, L Coyle, E Rozners
ACS chemical biology 17 (3), 509-512, 2022
102022
Amide modifications in the seed region of the guide strand improve the on-target specificity of short interfering RNA
M Richter, JA Viel, V Kotikam, PK Gajula, L Coyle, C Pal, E Rozners
ACS chemical biology 18 (1), 7-11, 2022
92022
Synthesis and properties of 2′-O-[R-and S-(2-amino-3-methoxy) propyl](R-AMP and S-AMP) nucleic acids
V Kotikam, VA Kumar
Tetrahedron 69 (31), 6404-6408, 2013
92013
Enzymatic beacons for specific sensing of dilute nucleic acid
X Zhang, V Kotikam, E Rozners, BP Callahan
ChemBioChem 23 (4), e202100594, 2022
62022
Enhanced splice correction by 3′, 5′-serinol and 2′-(ω-O-methylserinol) guarded OMe-RNA/DNA mixmers in cells
V Kotikam, AA Arzumanov, MJ Gait, VA Kumar
Artificial DNA: PNA & XNA 4 (3), 77-83, 2013
52013
Locked and unlocked 2'-o phosphoramidite nucleosides, process of preparation thereof and oligomers comprising the nucleosides
AK Vaijayanti, AD Gunjai, M D'costa, ND Erande, V Kotikam
US Patent App. 12/876,494, 2011
42011
Robust synthesis of enantiopure cyclohexenyl analogues of 2/3-deoxyribose sugars as carbocyclic nucleoside precursors
M Varada, V Kotikam, VA Kumar
Tetrahedron 67 (32), 5744-5749, 2011
32011
Inhibition of miR-21 by 3 [variant prime]/5 [variant prime]-Serinyl-Capped 2 [variant prime]-O-Methyl RNA Interspersed with 2 [variant prime]-O-(2-Amino-3-Methoxypropyl …
S Nahar, V Kotikam, VA Kumar, S Maiti
Nucleic Acid Therapeutics 26 (5), 327, 2016
12016
Enzymatic Beacons for Specific Sensing of Dilute Nucleic Acid and Potential Utility for SARS-CoV-2 Detection
X Zhang, V Kotikam, E Rozners, BP Callahan
bioRxiv, 2021
2021
2′/3′/5′-(R/S)-serinyl functionalized oligonucleotides
VA Kumar, V Kotikam, S Maiti, S Nahar
US Patent 9,920,319, 2018
2018
Synthesis and evaluation of designed (S)-polycarbamate nucleic acids, erythrulose-based-and 2'-functionalized-oligonucleotide analogs for RNA targeting
V Kotikam
CSIR-National Chemical Laboratory, Pune, 2013
2013
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