Theo dõi
A. Phillip West
A. Phillip West
The Jackson Laboratory
Email được xác minh tại jax.org - Trang chủ
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
AP West, IE Brodsky, C Rahner, DK Woo, H Erdjument-Bromage, ...
Nature 472 (7344), 476-480, 2011
17942011
Mitochondrial DNA stress primes the antiviral innate immune response
P West
Biophysical Journal 108 (2), 3a, 2015
16782015
NF-κB and the immune response
MS Hayden, AP West, S Ghosh
Oncogene 25 (51), 6758-6780, 2006
16322006
Mitochondria in innate immune responses
AP West, GS Shadel, S Ghosh
Nature Reviews Immunology 11 (6), 389-402, 2011
15162011
Recognition and signaling by toll-like receptors
AP West, AA Koblansky, S Ghosh
Annu. Rev. Cell Dev. Biol. 22 (1), 409-437, 2006
9672006
Mitochondrial DNA in innate immune responses and inflammatory pathology
AP West, GS Shadel
Nature Reviews Immunology 17 (6), 363-375, 2017
9292017
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
A Rongvaux, R Jackson, CCD Harman, T Li, AP West, MR De Zoete, ...
Cell 159 (7), 1563-1577, 2014
8102014
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1
B Zhao, F Du, P Xu, C Shu, B Sankaran, SL Bell, M Liu, Y Lei, X Gao, X Fu, ...
Nature 569 (7758), 718-722, 2019
3502019
Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes
SB Mizel, AN Honko, MA Moors, PS Smith, AP West
The Journal of Immunology 170 (12), 6217-6223, 2003
2662003
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
N Kerur, S Fukuda, D Banerjee, Y Kim, D Fu, I Apicella, A Varshney, ...
Nature medicine 24 (1), 50-61, 2018
2542018
Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
CG Weindel, EL Martinez, X Zhao, CJ Mabry, SL Bell, KJ Vail, ...
Cell 185 (17), 3214-3231. e23, 2022
2262022
IκBβ acts to inhibit and activate gene expression during the inflammatory response
P Rao, MS Hayden, M Long, ML Scott, AP West, D Zhang, A Oeckinghaus, ...
Nature 466 (7310), 1115-1119, 2010
2222010
The molecular basis of tight nuclear tethering and inactivation of cGAS
B Zhao, P Xu, CM Rowlett, T Jing, O Shinde, Y Lei, AP West, WR Liu, P Li
Nature 587 (7835), 673-677, 2020
2072020
Mitochondrial dysfunction as a trigger of innate immune responses and inflammation
AP West
Toxicology 391, 54-63, 2017
2002017
Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo
KF Yambire, C Rostosky, T Watanabe, D Pacheu-Grau, S Torres-Odio, ...
Elife 8, e51031, 2019
1972019
Identification of a sequence in human toll-like receptor 5 required for the binding of Gram-negative flagellin
SB Mizel, AP West, RR Hantgan
Journal of Biological Chemistry 278 (26), 23624-23629, 2003
1912003
Subversion of innate immune responses by Brucella through the targeted degradation of the TLR signaling adapter, MAL
D Sengupta, A Koblansky, J Gaines, T Brown, AP West, D Zhang, ...
The journal of immunology 184 (2), 956-964, 2010
1482010
Mitochondrial DNA stress signalling protects the nuclear genome
Z Wu, S Oeck, AP West, KC Mangalhara, AG Sainz, LE Newman, ...
Nature metabolism 1 (12), 1209-1218, 2019
1152019
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
Y Lei, JJ VanPortfliet, YF Chen, JD Bryant, Y Li, D Fails, S Torres-Odio, ...
Cell 186 (14), 3013-3032. e22, 2023
1102023
MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury
P Mannam, AS Shinn, A Srivastava, RF Neamu, WE Walker, M Bohanon, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 306 (7 …, 2014
1042014
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