Các bài viết có thể truy cập công khai - Francesco OrtusoTìm hiểu thêm
Không có ở bất kỳ nơi nào: 11
Discovery of new chemical entities for old targets: insights on the lead optimization of chromone-based monoamine oxidase B (MAO-B) inhibitors
J Reis, F Cagide, D Chavarria, T Silva, C Fernandes, A Gaspar, E Uriarte, ...
Journal of Medicinal Chemistry 59 (12), 5879-5893, 2016
Các cơ quan ủy nhiệm: Fundação para a Ciência e a Tecnologia, Portugal, European Commission
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors
J Reis, F Cagide, ME Valencia, J Teixeira, D Bagetta, C Perez, E Uriarte, ...
European Journal of Medicinal Chemistry 158, 781-800, 2018
Các cơ quan ủy nhiệm: Fundação para a Ciência e a Tecnologia, Portugal, European Commission …
Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?
L Parrotta, F Ortuso, F Moraca, R Rocca, G Costa, S Alcaro, A Artese
Expert opinion on drug discovery 9 (10), 1167-1187, 2014
Các cơ quan ủy nhiệm: Government of Italy
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data
A Artese, G Costa, S Distinto, F Moraca, F Ortuso, L Parrotta, S Alcaro
European Journal of Medicinal Chemistry 68, 139-149, 2013
Các cơ quan ủy nhiệm: Government of Italy
Hit Identification of a Novel Dual Binder for h‐telo/c‐myc G‐Quadruplex by a Combination of Pharmacophore Structure‐Based Virtual Screening and Docking Refinement
R Rocca, G Costa, A Artese, L Parrotta, F Ortuso, E Maccioni, O Pinato, ...
ChemMedChem 11 (16), 1721-1733, 2016
Các cơ quan ủy nhiệm: Government of Italy
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4′-biphenyl)-5-phenyl-4, 5-dihydro …
F Ortuso, S Alcaro, S Menta, R Fioravanti, R Cirilli
Journal of Chromatography A 1324, 71-77, 2014
Các cơ quan ủy nhiệm: US National Institutes of Health
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G‐quadruplex DNA c‐myc and bcl‐2 Sequences
G Costa, R Rocca, F Moraca, C Talarico, I Romeo, F Ortuso, S Alcaro, ...
Molecular Informatics 35 (8-9), 391-402, 2016
Các cơ quan ủy nhiệm: European Commission, Government of Italy
Synthesis, Monoamine Oxidase Inhibition and Computational Analysis of Diversely Substituted N‐Propargylated‐1, 3, 5‐triazines
M Chioua, A González‐Camuñas, MT Catarozzo, S Alcaro, F Ortuso, ...
ChemistrySelect 4 (28), 8334-8337, 2019
Các cơ quan ủy nhiệm: Government of Spain
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
J Reis, C Fernandes, H Salem, M Maia, C Tomé, S Benfeito, J Teixeira, ...
European Journal of Medicinal Chemistry 239, 114507, 2022
Các cơ quan ủy nhiệm: Fundação para a Ciência e a Tecnologia, Portugal, European Commission
From homology modeling to the hit identification and drug repurposing: a structure-based approach in the discovery of novel potential anti-obesity compounds
G Costa, A Artese, F Ortuso, S Alcaro
Protein-Ligand Interactions and Drug Design, 263-277, 2021
Các cơ quan ủy nhiệm: European Commission
Identification of SET/EED dual binders as innovative PRC2 inhibitors
R Catalano, A Maruca, R Rocca, P Tassone, G Panzarella, G Costa, ...
Future Medicinal Chemistry 14 (9), 609-621, 2022
Các cơ quan ủy nhiệm: European Commission, Government of Italy, AIRC Foundation for Cancer …
Có tại một số nơi: 44
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
F Moraca, J Amato, F Ortuso, A Artese, B Pagano, E Novellino, S Alcaro, ...
Proceedings of the National Academy of Sciences 114 (11), E2136-E2145, 2017
Các cơ quan ủy nhiệm: Swiss National Science Foundation, European Commission, Government of Italy
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome
D Bagetta, A Maruca, A Lupia, F Mesiti, R Catalano, I Romeo, F Moraca, ...
European journal of medicinal chemistry 186, 111903, 2020
Các cơ quan ủy nhiệm: European Commission, Government of Italy
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy
C Talarico, L D'Antona, D Scumaci, A Barone, F Gigliotti, CV Fiumara, ...
Oncotarget 6 (35), 37511, 2015
Các cơ quan ủy nhiệm: Government of Italy
SGK1, the new player in the game of resistance: chemo-radio molecular target and strategy for inhibition
C Talarico, V Dattilo, L D'antona, M Menniti, C Bianco, F Ortuso, S Alcaro, ...
Cellular physiology and biochemistry 39 (5), 1863-1876, 2016
Các cơ quan ủy nhiệm: Government of Italy
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells
C Talarico, V Dattilo, L D'Antona, A Barone, N Amodio, S Belviso, ...
Oncotarget 7 (13), 15868, 2016
Các cơ quan ủy nhiệm: US National Institutes of Health, Government of Italy
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile
A Maruca, R Catalano, D Bagetta, F Mesiti, FA Ambrosio, I Romeo, ...
European journal of medicinal chemistry 181, 111579, 2019
Các cơ quan ủy nhiệm: European Commission
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase …
OM Bautista-Aguilera, A Samadi, M Chioua, K Nikolic, S Filipic, D Agbaba, ...
Journal of medicinal chemistry 57 (24), 10455-10463, 2014
Các cơ quan ủy nhiệm: European Commission, Government of Spain
SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation
L D''antona, R Amato, C Talarico, F Ortuso, M Menniti, V Dattilo, R Iuliano, ...
Cellular physiology and biochemistry 35 (5), 2006-2018, 2015
Các cơ quan ủy nhiệm: Government of Italy
Structural genetics of circulating variants affecting the SARS-CoV-2 spike/human ACE2 complex
F Ortuso, D Mercatelli, PH Guzzi, FM Giorgi
Journal of Biomolecular Structure and Dynamics 40 (14), 6545-6555, 2022
Các cơ quan ủy nhiệm: Government of Italy
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