| Chalcones: a valid scaffold for monoamine oxidases inhibitors F Chimenti, R Fioravanti, A Bolasco, P Chimenti, D Secci, F Rossi, ... Journal of medicinal chemistry 52 (9), 2818-2824, 2009 | 249 | 2009 |
| Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins F Chimenti, D Secci, A Bolasco, P Chimenti, B Bizzarri, A Granese, ... Journal of medicinal chemistry 52 (7), 1935-1942, 2009 | 196 | 2009 |
| Synthesis and biological evaluation of N-substituted-3, 5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors R Fioravanti, A Bolasco, F Manna, F Rossi, F Orallo, F Ortuso, S Alcaro, ... European journal of medicinal chemistry 45 (12), 6135-6138, 2010 | 181 | 2010 |
| Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors A Gaspar, T Silva, M Yánez, D Vina, F Orallo, F Ortuso, E Uriarte, S Alcaro, ... Journal of medicinal chemistry 54 (14), 5165-5173, 2011 | 166 | 2011 |
| Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3, 5-diaryl-4, 5-dihydro-(1 H)-pyrazole derivatives F Chimenti, E Maccioni, D Secci, A Bolasco, P Chimenti, A Granese, ... Journal of medicinal chemistry 48 (23), 7113-7122, 2005 | 164 | 2005 |
| Quercetin as the Active Principle of Hypericum hircinum Exerts a Selective Inhibitory Activity against MAO-A: Extraction, Biological Analysis, and Computational … F Chimenti, F Cottiglia, L Bonsignore, L Casu, M Casu, C Floris, D Secci, ... Journal of natural products 69 (6), 945-949, 2006 | 149 | 2006 |
| GBPM: GRID-based pharmacophore model: concept and application studies to protein–protein recognition F Ortuso, T Langer, S Alcaro Bioinformatics 22 (12), 1449-1455, 2006 | 130 | 2006 |
| Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study F Chimenti, D Secci, A Bolasco, P Chimenti, A Granese, O Befani, P Turini, ... Bioorganic & medicinal chemistry letters 14 (14), 3697-3703, 2004 | 129 | 2004 |
| A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors F Chimenti, R Fioravanti, A Bolasco, P Chimenti, D Secci, F Rossi, ... Bioorganic & medicinal chemistry 18 (3), 1273-1279, 2010 | 126 | 2010 |
| Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations F Moraca, J Amato, F Ortuso, A Artese, B Pagano, E Novellino, S Alcaro, ... Proceedings of the National Academy of Sciences 114 (11), E2136-E2145, 2017 | 125 | 2017 |
| Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors A Procopio, S Alcaro, M Nardi, M Oliverio, F Ortuso, P Sacchetta, ... Journal of agricultural and food chemistry 57 (23), 11161-11167, 2009 | 124 | 2009 |
| Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives D Secci, S Carradori, A Bolasco, P Chimenti, M Yáñez, F Ortuso, S Alcaro European journal of medicinal chemistry 46 (10), 4846-4852, 2011 | 120 | 2011 |
| Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives F Chimenti, E Maccioni, D Secci, A Bolasco, P Chimenti, A Granese, ... Journal of medicinal chemistry 50 (4), 707-712, 2007 | 120 | 2007 |
| Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl) hydrazones F Chimenti, E Maccioni, D Secci, A Bolasco, P Chimenti, A Granese, ... Journal of medicinal chemistry 51 (16), 4874-4880, 2008 | 112 | 2008 |
| Modeling and biological evaluation of 3, 3′-(1, 2-ethanediyl) bis [2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor R Ottaná, E Mazzon, L Dugo, F Monforte, R Maccari, L Sautebin, ... European Journal of Pharmacology 448 (1), 71-80, 2002 | 109 | 2002 |
| Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties N Desideri, A Bolasco, R Fioravanti, L Proietti Monaco, F Orallo, M Yáñez, ... Journal of medicinal chemistry 54 (7), 2155-2164, 2011 | 108 | 2011 |
| Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors F Chimenti, A Bolasco, D Secci, P Chimenti, A Granese, S Carradori, ... Bioorganic & medicinal chemistry 18 (15), 5715-5723, 2010 | 106 | 2010 |
| Discovery of new chemical entities for old targets: insights on the lead optimization of chromone-based monoamine oxidase B (MAO-B) inhibitors J Reis, F Cagide, D Chavarria, T Silva, C Fernandes, A Gaspar, E Uriarte, ... Journal of Medicinal Chemistry 59 (12), 5879-5893, 2016 | 102 | 2016 |
| Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches S Alcaro, C Musetti, S Distinto, M Casatti, G Zagotto, A Artese, L Parrotta, ... Journal of medicinal chemistry 56 (3), 843-855, 2013 | 100 | 2013 |
| N-myristoylation determines dual targeting of mammalian NADH-cytochrome b (5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning S Colombo, R Longhi, S Alcaro, F Ortuso, T Sprocati, A Flora, N Borgese The Journal of cell biology 168 (5), 735-745, 2005 | 99 | 2005 |