Các bài viết có thể truy cập công khai - John P. OveringtonTìm hiểu thêm
Không có ở bất kỳ nơi nào: 2
Meeting the discovery challenge of drug-resistant infections: progress and focusing resources
G Dougan, C Dowson, J Overington, NGADS Participants
Drug discovery today 24 (2), 452-461, 2019
Các cơ quan ủy nhiệm: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
Drug discovery and development in the era of big data
J Bajorath, J Overington, JL Jenkins, P Walters
Future Medicinal Chemistry 8 (15), 1807-1813, 2016
Các cơ quan ủy nhiệm: European Commission
Có tại một số nơi: 55
ChEMBL: a large-scale bioactivity database for drug discovery
A Gaulton, LJ Bellis, AP Bento, J Chambers, M Davies, A Hersey, Y Light, ...
Nucleic Acids Research 40, D1100-1107, 2012
Các cơ quan ủy nhiệm: Cancer Research UK
The ChEMBL database in 2017
A Gaulton, A Hersey, M Nowotka, AP Bento, J Chambers, D Mendez, ...
Nucleic acids research 45 (D1), D945-D954, 2017
Các cơ quan ủy nhiệm: US National Institutes of Health, Wellcome Trust
A comprehensive map of molecular drug targets
R Santos, O Ursu, A Gaulton, AP Bento, RS Donadi, CG Bologa, ...
Nature reviews Drug discovery 16 (1), 19-34, 2017
Các cơ quan ủy nhiệm: US National Institutes of Health, Cancer Research UK, Wellcome Trust
The ChEMBL bioactivity database: an update
AP Bento, A Gaulton, A Hersey, LJ Bellis, J Chambers, M Davies, ...
Nucleic acids research 42 (D1), D1083-D1090, 2014
Các cơ quan ủy nhiệm: UK Engineering and Physical Sciences Research Council, Wellcome Trust
An atlas of genetic influences on human blood metabolites
SY Shin, EB Fauman, AK Petersen, J Krumsiek, R Santos, J Huang, ...
Nature Genetics 46, 543-540, 2014
Các cơ quan ủy nhiệm: US National Institutes of Health, Canadian Institutes of Health Research …
The genome of the blood fluke Schistosoma mansoni
M Berriman, BJ Haas, PT LoVerde, RA Wilson, GP Dillon, GC Cerqueira, ...
Nature 460 (7253), 352-358, 2009
Các cơ quan ủy nhiệm: US National Institutes of Health
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
Các cơ quan ủy nhiệm: US National Institutes of Health, Cancer Research UK, UK Medical Research …
A community effort to assess and improve drug sensitivity prediction algorithms.
WK Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M ...
Nat Biotechnol. 32 (6), 2014
Các cơ quan ủy nhiệm: US National Institutes of Health, Howard Hughes Medical Institute
ChEMBL web services: streamlining access to drug discovery data and utilities
M Davies, M Nowotka, G Papadatos, N Dedman, A Gaulton, F Atkinson, ...
Nucleic acids research 43 (W1), W612-W620, 2015
Các cơ quan ủy nhiệm: Wellcome Trust
The druggable genome and support for target identification and validation in drug development
C Finan, A Gaulton, FA Kruger, RT Lumbers, T Shah, J Engmann, ...
Science translational medicine 9 (383), eaag1166, 2017
Các cơ quan ủy nhiệm: European Molecular Biology Laboratory, British Heart Foundation, National …
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317-332, 2018
Các cơ quan ủy nhiệm: US National Institutes of Health, European Molecular Biology Laboratory …
Genomic-scale prioritization of drug targets: the TDR Targets database
F Agüero, B Al-Lazikani, M Aslett, M Berriman, FS Buckner, RK Campbell, ...
Nature reviews Drug discovery 7 (11), 900-907, 2008
Các cơ quan ủy nhiệm: US National Institutes of Health
Comprehensive characterization of the published kinase inhibitor set
JM Elkins, V Fedele, M Szklarz, KR Abdul Azeez, E Salah, J Mikolajczyk, ...
Nature biotechnology 34 (1), 95-103, 2016
Các cơ quan ủy nhiệm: Genome Canada, British Heart Foundation, Wellcome Trust
A community computational challenge to predict the activity of pairs of compounds
M Bansal, J Yang, C Karan, MP Menden, JC Costello, H Tang, G Xiao, ...
Nature biotechnology 32 (12), 1213-1222, 2014
Các cơ quan ủy nhiệm: US National Institutes of Health, Howard Hughes Medical Institute, Wellcome …
PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease
AF Schmidt, LS Pearce, JT Wilkins, JP Overington, AD Hingorani, ...
Cochrane Database of Systematic Reviews, 2017
Các cơ quan ủy nhiệm: British Heart Foundation, National Institute for Health Research, UK
PSICQUIC and PSISCORE: accessing and scoring molecular interactions
B Aranda, H Blankenburg, S Kerrien, FSL Brinkman, A Ceol, E Chautard, ...
Nature Methods 8 (7), 528-529, 2011
Các cơ quan ủy nhiệm: US National Institutes of Health, Canadian Institutes of Health Research …
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
Các cơ quan ủy nhiệm: US National Institutes of Health
Improving the odds of drug development success through human genomics: modelling study
AD Hingorani, V Kuan, C Finan, FA Kruger, A Gaulton, S Chopade, ...
Scientific reports 9 (1), 18911, 2019
Các cơ quan ủy nhiệm: European Molecular Biology Laboratory, Versus Arthritis, UK, British Heart …
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