Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis A Ordureau, SA Sarraf, DM Duda, JM Heo, MP Jedrychowski, ... Molecular cell 56 (3), 360-375, 2014 | 745 | 2014 |
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors N Maheshri, JT Koerber, BK Kaspar, DV Schaffer Nature biotechnology 24 (2), 198-204, 2006 | 694 | 2006 |
A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery ML Forrest, JT Koerber, DW Pack Bioconjugate chemistry 14 (5), 934-940, 2003 | 534 | 2003 |
Partial Acetylation of Polyethylenimine Enhances In Vitro Gene Delivery ML Forrest, GE Meister, JT Koerber, DW Pack Pharmaceutical research 21, 365-371, 2004 | 313 | 2004 |
A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer PloS one 4 (10), e7467, 2009 | 242 | 2009 |
Directed evolution of adeno-associated virus to an infectious respiratory virus KJDA Excoffon, JT Koerber, DD Dickey, M Murtha, S Keshavjee, ... Proceedings of the National Academy of Sciences 106 (10), 3865-3870, 2009 | 228 | 2009 |
DNA shuffling of adeno-associated virus yields functionally diverse viral progeny JT Koerber, JH Jang, DV Schaffer Molecular Therapy 16 (10), 1703-1709, 2008 | 227 | 2008 |
Molecular engineering of viral gene delivery vehicles DV Schaffer, JT Koerber, K Lim Annu. Rev. Biomed. Eng. 10 (1), 169-194, 2008 | 220 | 2008 |
Molecular evolution of adeno-associated virus for enhanced glial gene delivery JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer Molecular Therapy 17 (12), 2088-2095, 2009 | 219 | 2009 |
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal KM Storek, MR Auerbach, H Shi, NK Garcia, D Sun, NN Nickerson, R Vij, ... Proceedings of the National Academy of Sciences 115 (14), 3692-3697, 2018 | 185 | 2018 |
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab L Rougé, N Chiang, M Steffek, C Kugel, TI Croll, C Tam, A Estevez, ... Science 367 (6483), 1224-1230, 2020 | 163 | 2020 |
Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3 D Slaga, D Ellerman, TN Lombana, R Vij, J Li, M Hristopoulos, R Clark, ... Science translational medicine 10 (463), eaat5775, 2018 | 139 | 2018 |
An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells JH Jang, JT Koerber, JS Kim, P Asuri, T Vazin, M Bartel, A Keung, I Kwon, ... Molecular Therapy 19 (4), 667-675, 2011 | 129 | 2011 |
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehicles JT Koerber, N Maheshri, BK Kaspar, DV Schaffer Nature protocols 1 (2), 701-706, 2006 | 108 | 2006 |
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ... Cell 179 (2), 417-431. e19, 2019 | 97 | 2019 |
Adeno-associated virus virions with variant capsid and methods of use thereof DV Schaffer, RR Klimczak, JT Koerber, JG Flannery, DD Mourot, M Visel, ... US Patent 9,193,956, 2015 | 92 | 2015 |
Nature-inspired design of motif-specific antibody scaffolds JT Koerber, ND Thomsen, BT Hannigan, WF Degrado, JA Wells Nature biotechnology 31 (10), 916-921, 2013 | 88 | 2013 |
Adeno-associated virus virions with variant capsid and methods of use thereof DV Schaffer, RR Klimczak, JT Koerber, JG Flannery US Patent 9,457,103, 2016 | 79 | 2016 |
Structural snapshots reveal distinct mechanisms of procaspase-3 and-7 activation ND Thomsen, JT Koerber, JA Wells Proceedings of the National Academy of Sciences 110 (21), 8477-8482, 2013 | 79 | 2013 |
Engineering adeno-associated virus for one-step purification via immobilized metal affinity chromatography JT Koerber, JH Jang, JH Yu, RS Kane, DV Schaffer Human gene therapy 18 (4), 367-378, 2007 | 77 | 2007 |