| Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli Y Yang, S Fang, JP Jensen, AM Weissman, JD Ashwell Science 288 (5467), 874-877, 2000 | 1313 | 2000 |
| Glucocorticoids in T cell development and function JD Ashwell, FWM Lu, MS Vacchio Annual review of immunology 18 (1), 309-345, 2000 | 1076 | 2000 |
| Outer membrane vesicles of a human commensal mediate immune regulation and disease protection Y Shen, MLG Torchia, GW Lawson, CL Karp, JD Ashwell, SK Mazmanian Cell host & microbe 12 (4), 509-520, 2012 | 687 | 2012 |
| Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation CJ Wu, DB Conze, T Li, SM Srinivasula, JD Ashwell Nature cell biology 8 (4), 398-406, 2006 | 663 | 2006 |
| IAPs: what's in a name? SM Srinivasula, JD Ashwell Molecular cell 30 (2), 123-135, 2008 | 639 | 2008 |
| Genomic instability in Gadd45a-deficient mice MC Hollander, MS Sheikh, DV Bulavin, K Lundgren, L Augeri-Henmueller, ... Nature genetics 23 (2), 176-184, 1999 | 636 | 1999 |
| TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2 X Li, Y Yang, JD Ashwell Nature 416 (6878), 345-347, 2002 | 584 | 2002 |
| The many paths to p38 mitogen-activated protein kinase activation in the immune system JD Ashwell Nature Reviews Immunology 6 (7), 532-540, 2006 | 502 | 2006 |
| Failure to synthesize the T cell CD3-ζ chain: structure and function of a partial T cell receptor complex JJ Sussman, JS Bonifacino, J Lippincott-Schwartz, AM Weissman, T Saito, ... Cell 52 (1), 85-95, 1988 | 461 | 1988 |
| Steroid production in the thymus: implications for thymocyte selection. MS Vacchio, V Papadopoulos, JD Ashwell The Journal of experimental medicine 179 (6), 1835-1846, 1994 | 451 | 1994 |
| Programmed T lymphocyte death. Cell activation-and steroid-induced pathways are mutually antagonistic. CM Zacharchuk, M Merćep, PK Chakraborti, SS Simons Jr, JD Ashwell Journal of immunology (Baltimore, Md.: 1950) 145 (12), 4037-4045, 1990 | 424 | 1990 |
| Genetic and mutational analysis of the T-cell antigen receptor. JD Ashwell, RD Klusner Annual review of immunology 8, 139-167, 1990 | 417 | 1990 |
| Alternative p38 activation pathway mediated by T cell receptor–proximal tyrosine kinases JM Salvador, PR Mittelstadt, T Guszczynski, TD Copeland, H Yamaguchi, ... Nature immunology 6 (4), 390-395, 2005 | 406 | 2005 |
| Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells. MK Jenkins, JD Ashwell, RH Schwartz Journal of immunology (Baltimore, Md.: 1950) 140 (10), 3324-3330, 1988 | 400 | 1988 |
| Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ PR Mittelstadt, JD Ashwell Journal of Biological Chemistry 276 (31), 29603-29610, 2001 | 374 | 2001 |
| Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP G Zhu, CJ Wu, Y Zhao, JD Ashwell Current Biology 17 (16), 1438-1443, 2007 | 322 | 2007 |
| Cell growth cycle block of T cell hybridomas upon activation with antigen. JD Ashwell, RE Cunningham, PD Noguchi, D Hernandez The Journal of experimental medicine 165 (1), 173-194, 1987 | 309 | 1987 |
| Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis JM Lenczowski, L Domínguez, AM Eder, LB King, CM Zacharchuk, ... Molecular and cellular biology 17 (1), 170-181, 1997 | 308 | 1997 |
| Structural basis for recognition of diubiquitins by NEMO YC Lo, SC Lin, CC Rospigliosi, DB Conze, CJ Wu, JD Ashwell, D Eliezer, ... Molecular cell 33 (5), 602-615, 2009 | 306 | 2009 |
| Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor-and toll-like receptor-mediated NF-κB activation DB Conze, CJ Wu, JA Thomas, A Landstrom, JD Ashwell Molecular and cellular biology 28 (10), 3538-3547, 2008 | 296 | 2008 |
