| Prediction and reduction of the aggregation of monoclonal antibodies R van der Kant, AR Karow-Zwick, J Van Durme, M Blech, R Gallardo, ... Journal of molecular biology 429 (8), 1244-1261, 2017 | 168 | 2017 |
| GPCRDB: an information system for G protein-coupled receptors V Isberg, B Vroling, R van der Kant, K Li, G Vriend, D Gloriam Nucleic acids research 42 (D1), D422-D425, 2014 | 157 | 2014 |
| Hsp90 mediates membrane deformation and exosome release E Lauwers, YC Wang, R Gallardo, R Van der Kant, E Michiels, J Swerts, ... Molecular cell 71 (5), 689-702. e9, 2018 | 153 | 2018 |
| Solubis: a webserver to reduce protein aggregation through mutation J Van Durme, G De Baets, R Van Der Kant, M Ramakers, A Ganesan, ... Protein Engineering, Design and Selection 29 (8), 285-289, 2016 | 73 | 2016 |
| Structural hot spots for the solubility of globular proteins A Ganesan, A Siekierska, J Beerten, M Brams, J Van Durme, G De Baets, ... Nature communications 7 (1), 10816, 2016 | 73 | 2016 |
| Post-translational control of the temporal dynamics of transcription factor activity regulates neurogenesis XJ Quan, L Yuan, L Tiberi, A Claeys, N De Geest, J Yan, R Van Der Kant, ... Cell 164 (3), 460-475, 2016 | 69 | 2016 |
| Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia E Van Nieuwenhove, JS Barber, J Neumann, E Smeets, M Willemsen, ... Journal of Allergy and Clinical Immunology 146 (5), 1180-1193, 2020 | 44 | 2020 |
| Thermodynamic and evolutionary coupling between the native and amyloid state of globular proteins T Langenberg, R Gallardo, R van der Kant, N Louros, E Michiels, ... Cell reports 31 (2), 2020 | 44 | 2020 |
| Alpha-bulges in G protein-coupled receptors R Van der Kant, G Vriend International journal of molecular sciences 15 (5), 7841-7864, 2014 | 44 | 2014 |
| Reverse engineering synthetic antiviral amyloids E Michiels, K Roose, R Gallardo, L Khodaparast, L Khodaparast, ... Nature communications 11 (1), 2832, 2020 | 39 | 2020 |
| Thermodynamic analysis of amyloid fibril structures reveals a common framework for stability in amyloid polymorphs R van der Kant, N Louros, J Schymkowitz, F Rousseau Structure 30 (8), 1178-1189. e3, 2022 | 35* | 2022 |
| Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues B Houben, E Michiels, M Ramakers, K Konstantoulea, N Louros, ... The EMBO journal 39 (11), e102864, 2020 | 35 | 2020 |
| Solubis: optimize your protein G De Baets, J Van Durme, R van der Kant, J Schymkowitz, F Rousseau Bioinformatics 31 (15), 2580-2582, 2015 | 29 | 2015 |
| Adaption of human antibody λ and κ light chain architectures to CDR repertoires R van der Kant, J Bauer, AR Karow-Zwick, S Kube, P Garidel, M Blech, ... Protein Engineering, Design and Selection 32 (3), 109-127, 2019 | 17 | 2019 |
| StAmP-DB: a platform for structures of polymorphic amyloid fibril cores N Louros, R Van Der Kant, J Schymkowitz, F Rousseau Bioinformatics 38 (9), 2636-2638, 2022 | 15 | 2022 |
| SolubiS: Optimizing protein solubility by minimal point mutations R van der Kant, J van Durme, F Rousseau, J Schymkowitz Protein Misfolding Diseases: Methods and Protocols, 317-333, 2019 | 13 | 2019 |
| The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis N Guthertz, R Van Der Kant, RM Martinez, Y Xu, CH Trinh, BI Iorga, ... Proceedings of the National Academy of Sciences 119 (22), e2200468119, 2022 | 11 | 2022 |
| Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein K Janssen, F Claes, D Van de Velde, VL Wehbi, B Houben, Y Lampi, ... Proceedings of the National Academy of Sciences 120 (9), e2214921120, 2023 | 6 | 2023 |
| Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V F Claes, S Rudyak, AS Laird, N Louros, J Beerten, M Debulpaep, ... Protein Engineering, Design and Selection 32 (10), 443-457, 2019 | 6 | 2019 |
| De novodesign of high-affinity single-domain antibodies R van der Kant, Z Zhang, I Marković, D Vizarraga, T Garcia, K Maragkou, ... | 4 | 2024 |
Nikolaos LourosAssistant Professor, UT Soutwestern Medical CenterEmail được xác minh tại utsouthwestern.edu
Emiel MichielsPostdoc, VIB-KULeuven UniversityEmail được xác minh tại kuleuven.be
Bert HoubenPhD Researcher, VIB KULeuvenEmail được xác minh tại kuleuven.be
Tobias LangenbergVIBEmail được xác minh tại vib.be
Vriend GDirector BIPS Mindoro PhilippinesEmail được xác minh tại radboudumc.nl
Chris UlensKU LeuvenEmail được xác minh tại kuleuven.be
Daniel SeeligerBoehringer IngelheimEmail được xác minh tại boehringer-ingelheim.com
Maxime SiemonsThe Janssen Pharmaceutical Companies of Johnson & JohnsonEmail được xác minh tại its.jnj.com
Johan NeytsProfessor of Virology @KU Leuven; Co-Founder AstriVax Therapeutics & VirusbankPlatformEmail được xác minh tại rega.kuleuven.be
Guy BormansProfessor KU LeuvenEmail được xác minh tại kuleuven.be
Lorena Itati IbañezInstituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE)Email được xác minh tại qi.fcen.uba.ar
Vignir IsbergSenior Manager, NovonesisEmail được xác minh tại vignir.org
David E. GloriamDepartment of Drug Design and Pharmacology, University of CopenhagenEmail được xác minh tại sund.ku.dk
Kang LiDepartment of Mathmatical Sciences, University of CopenhagenEmail được xác minh tại math.ku.dkNatalia V. GounkoUTSWEmail được xác minh tại utsouthwestern.edu
Shelli McAlpineVisiting Professor, University of California, IrvineEmail được xác minh tại uci.edu
Ramon Duran-RomañaPost-doctoral researcher at VIB Switch LabEmail được xác minh tại kuleuven.be
Bassem HassanInserm Research Director and Team Leader, Paris Brain InstituteEmail được xác minh tại icm-institute.org
Mathieu BollenProfessor of Molecular Cell Biology, University of Leuven, BelgiumEmail được xác minh tại kuleuven.be