| A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ... Molecular cell 73 (4), 714-726. e4, 2019 | 269 | 2019 |
| Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice P Liu, SQ Liang, C Zheng, E Mintzer, YG Zhao, K Ponnienselvan, A Mir, ... Nature communications 12 (1), 2121, 2021 | 247 | 2021 |
| Type II-C CRISPR-Cas9 biology, mechanism, and application A Mir, A Edraki, J Lee, EJ Sontheimer ACS chemical biology 13 (2), 357-365, 2018 | 180 | 2018 |
| NmeCas9 is an intrinsically high-fidelity genome-editing platform N Amrani, XD Gao, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, KE Sasaki, ... Genome Biology 19, 1-25, 2018 | 145 | 2018 |
| C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2 XD Gao, LC Tu, A Mir, T Rodriguez, Y Ding, J Leszyk, J Dekker, ... Nature methods 15 (6), 433-436, 2018 | 144 | 2018 |
| All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo R Ibraheim, CQ Song, A Mir, N Amrani, W Xue, EJ Sontheimer Genome Biology, 2018 | 117 | 2018 |
| Heavily and Fully Modified RNAs Guide Efficient SpyCas9-Mediated Genome Editing A Mir, JF Alterman, MR Hassler, AJ Debacker, E Hudgens, D Echeverria, ... Nature Communications, 2018 | 116 | 2018 |
| Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 anti-CRISPR proteins J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ... MBio 9 (6), 10.1128/mbio. 02321-18, 2018 | 98 | 2018 |
| Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ... Nature communications 12 (1), 6267, 2021 | 85 | 2021 |
| Two active site divalent ions in the crystal structure of the hammerhead ribozyme bound to a transition state analogue A Mir, BL Golden Biochemistry 55 (4), 633-636, 2016 | 84 | 2016 |
| Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction A Mir, J Chen, K Robinson, E Lendy, J Goodman, D Neau, BL Golden Biochemistry 54 (41), 6369-6381, 2015 | 80 | 2015 |
| 5′ Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing 2 KS Ghanta, GA Dokshin, A Mir, PM Krishnamurthy | 56 | 2018 |
| Anti-CRISPR AcrIIA5 potently inhibits all Cas9 homologs used for genome editing B Garcia, J Lee, A Edraki, Y Hidalgo-Reyes, S Erwood, A Mir, CN Trost, ... Cell reports 29 (7), 1739-1746. e5, 2019 | 51 | 2019 |
| Nucleic acid-guided nucleases J Kim, B Mijts, A Mir, A Garst, K Seamon US Patent 10,745,678, 2020 | 47 | 2020 |
| Nucleic acid-guided nucleases J Kim, B Mijts, A Mir, A Garst, K Seamon US Patent 10,724,021, 2020 | 47 | 2020 |
| Nucleic acid-guided nucleases J Kim, B Mijts, A Mir, A Garst, K Seamon US Patent 10,704,033, 2020 | 47 | 2020 |
| Nucleic acid-guided nucleases J Kim, B Mijts, A Mir, A Garst, K Seamon US Patent 10,767,169, 2020 | 39 | 2020 |
| Efficient homology-directed repair with circular single-stranded DNA donors S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ... The CRISPR journal 5 (5), 685-701, 2022 | 32 | 2022 |
| Automated multi-module cell processing methods, instruments, and systems E Feldman, B Mijts, A Mir, E Zimmerman, A Garst US Patent 10,689,669, 2020 | 17 | 2020 |
| Efficient homology-directed repair with circular ssDNA donors S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ... bioRxiv, 864199, 2019 | 11 | 2019 |