Kamu erişimi zorunlu olan makaleler - James Edward LongbothamDaha fazla bilgi edinin
Bir yerde sunuluyor: 11
Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling
JE Longbotham, CM Chio, V Dharmarajan, MJ Trnka, IO Torres, ...
Nature communications 10 (1), 94, 2019
Zorunlu olanlar: US National Institutes of Health
Convergence of theory and experiment on the role of preorganization, quantum tunneling, and enzyme motions into flavoenzyme-catalyzed hydride transfer
M Delgado, S Gorlich, JE Longbotham, NS Scrutton, S Hay, V Moliner, ...
ACS catalysis 7 (5), 3190-3198, 2017
Zorunlu olanlar: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Untangling heavy protein and cofactor isotope effects on enzyme-catalyzed hydride transfer
JE Longbotham, SJO Hardman, S Gorlich, NS Scrutton, S Hay
Journal of the American Chemical Society 138 (41), 13693-13699, 2016
Zorunlu olanlar: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Structure and mechanism of a viral collagen prolyl hydroxylase
JE Longbotham, C Levy, LO Johannissen, H Tarhonskaya, S Jiang, ...
Biochemistry 54 (39), 6093-6105, 2015
Zorunlu olanlar: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2
IP Chen, JE Longbotham, S McMahon, RK Suryawanshi, MM Khalid, ...
Cell Reports 40 (3), 2022
Zorunlu olanlar: US National Institutes of Health
Extended recognition of the histone H3 tail by histone demethylase KDM5A
N Petronikolou, JE Longbotham, DG Fujimori
Biochemistry 59 (5), 647-651, 2020
Zorunlu olanlar: US National Institutes of Health
Recognition of histone H3 methylation states by the PHD1 domain of histone demethylase KDM5A
JE Longbotham, MJS Kelly, DG Fujimori
ACS Chemical Biology, 2021
Zorunlu olanlar: US National Institutes of Health
Domain cross-talk in regulation of histone modifications: molecular mechanisms and targeting opportunities
JE Longbotham, MY Zhang, DG Fujimori
Current opinion in chemical biology 57, 105-113, 2020
Zorunlu olanlar: US National Institutes of Health
Exploring the ligand preferences of the PHD1 domain of histone demethylase KDM5A reveals tolerance for modifications of the Q5 residue of histone 3
SE Anderson, JE Longbotham, PT O’Kane, FS Ugur, DG Fujimori, ...
ACS chemical biology 16 (1), 205-213, 2020
Zorunlu olanlar: US Department of Defense, US National Institutes of Health
Identifying ligands for the PHD1 finger of KDM5A through high-throughput screening
G Ortiz, JE Longbotham, SL Qin, MY Zhang, GM Lee, RJ Neitz, MJS Kelly, ...
RSC Chemical Biology 5 (3), 209-215, 2024
Zorunlu olanlar: US National Institutes of Health
Dissecting contributions of catalytic and reader domains in regulation of histone demethylation
N Petronikolou, JE Longbotham, DG Fujimori
Methods in enzymology 639, 217-236, 2020
Zorunlu olanlar: US National Institutes of Health
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