| A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality BA Buckley, KB Burkhart, SG Gu, G Spracklin, A Kershner, H Fritz, ... Nature 489 (7416), 447-451, 2012 | 567 | 2012 |
| Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint SG Gu, J Pak, S Guang, JM Maniar, S Kennedy, A Fire Nature Genetics 44 (2), 157-164, 2012 | 308 | 2012 |
| Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls D Witten, R Tibshirani, S Gu, A Fire, WO Lui BMC biology 8 (1), 58, 2010 | 227 | 2010 |
| Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites S Sasaki, CC Mello, A Shimada, Y Nakatani, S Hashimoto, M Ogawa, ... Science 323 (5912), 401-404, 2009 | 148 | 2009 |
| A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans JZ Ni, N Kalinava, E Chen, A Huang, T Trinh, SG Gu Epigenetics & chromatin 9 (1), 3, 2016 | 118 | 2016 |
| A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference JI Gent, M Schvarzstein, AM Villeneuve, SG Gu, V Jantsch, AZ Fire, ... Genetics 183 (4), 1297-1314, 2009 | 115 | 2009 |
| Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan M Vora, M Shah, S Ostafi, B Onken, J Xue, JZ Ni, S Gu, M Driscoll PLoS Genetics 9 (8), e1003737, 2013 | 89 | 2013 |
| Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated … N Kalinava, JZ Ni, K Peterman, E Chen, SG Gu Epigenetics & Chromatin 10 (1), 6, 2017 | 83 | 2017 |
| Partitioning the C. elegans genome by nucleosome modification, occupancy, and positioning SG Gu, A Fire Chromosoma 119 (1), 73-87, 2010 | 68 | 2010 |
| MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality NE Weiser, DX Yang, S Feng, N Kalinava, KC Brown, J Khanikar, ... Developmental Cell 41 (4), 408-423. e7, 2017 | 67 | 2017 |
| Complex coding of endogenous siRNA, transcriptional silencing and H3K9 methylation on native targets of germline nuclear RNAi in C. elegans JZ Ni, E Chen, SG Gu BMC Genomics 15 (1), 1157, 2014 | 64 | 2014 |
| The Transcription Start Site Landscape of C. elegans TL Saito, S Hashimoto, SG Gu, JJ Morton, M Stadler, T Blumenthal, A Fire, ... Genome research, 2013 | 64 | 2013 |
| C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing N Kalinava, JZ Ni, Z Gajic, M Kim, H Ushakov, SG Gu Cell reports 25 (8), 2273-2284. e3, 2018 | 55 | 2018 |
| The conformation of microRNA seed regions in native microRNPs is prearranged for presentation to mRNA targets NJ Lambert, SG Gu, AM Zahler Nucleic Acids Research 39 (11), 4827-4835, 2011 | 55 | 2011 |
| The zinc transporter ZIPT-7.1 regulates sperm activation in nematodes Y Zhao, CH Tan, A Krauchunas, A Scharf, N Dietrich, K Warnhoff, Z Yuan, ... PLoS biology 16 (6), e2005069, 2018 | 46 | 2018 |
| Caenorhabditis elegans nuclear RNAi factor SET-32 deposits the transgenerational histone modification, H3K23me3 L Schwartz-Orbach, C Zhang, S Sidoli, R Amin, D Kaur, A Zhebrun, J Ni, ... Elife 9, e54309, 2020 | 45 | 2020 |
| Reprogramming the piRNA pathway for multiplexed and transgenerational gene silencing in C. elegans M Priyadarshini, JZ Ni, AM Vargas-Velazquez, SG Gu, C Frøkjær-Jensen Nature methods 19 (2), 187-194, 2022 | 36 | 2022 |
| Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans SG Gu, J Pak, S Barberan-Soler, M Ali, A Fire, AM Zahler RNA 13 (9), 1492-1504, 2007 | 30 | 2007 |
| Distributed probing of chromatin structure in vivo reveals pervasive chromatin accessibility for expressed and non-expressed genes during tissue differentiation in C. elegans K Sha, SG Gu, LC Pantalena-Filho, A Goh, J Fleenor, D Blanchard, ... BMC genomics 11 (1), 465, 2010 | 27 | 2010 |
| The spatial and temporal dynamics of nuclear RNAi-targeted retrotransposon transcripts in Caenorhabditis elegans JZ Ni, N Kalinava, SG Mendoza, SG Gu Development 145 (20), dev167346, 2018 | 15 | 2018 |
