| High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability LWT Cheung, BT Hennessy, J Li, S Yu, AP Myers, B Djordjevic, Y Lu, ... Cancer discovery 1 (2), 170-185, 2011 | 533 | 2011 |
| The genomic landscape and clinical relevance of A-to-I RNA editing in human cancers L Han, L Diao, S Yu, X Xu, J Li, R Zhang, Y Yang, HMJ Werner, ... Cancer cell 28 (4), 515-528, 2015 | 517 | 2015 |
| Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer H Liang, LWT Cheung, J Li, Z Ju, S Yu, K Stemke-Hale, T Dogruluk, Y Lu, ... Genome research 22 (11), 2120-2129, 2012 | 319 | 2012 |
| Systematic Functional Annotation of Somatic Mutations in Cancer PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ... Cancer cell 33 (3), 450-462. e10, 2018 | 294 | 2018 |
| Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor α SH Park, LWT Cheung, AST Wong, PCK Leung Molecular endocrinology 22 (9), 2085-2098, 2008 | 271 | 2008 |
| Gonadotropin‐releasing hormone: GnRH receptor signaling in extrapituitary tissues LWT Cheung, AST Wong The FEBS journal 275 (22), 5479-5495, 2008 | 171 | 2008 |
| Ginsenoside Rb1 inhibits tube‐like structure formation of endothelial cells by regulating pigment epithelium‐derived factor through the oestrogen β receptor KW Leung, LWT Cheung, YL Pon, RNS Wong, NK Mak, TPD Fan, SCL Au, ... British journal of pharmacology 152 (2), 207-215, 2007 | 139 | 2007 |
| Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase–mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 LWT Cheung, PCK Leung, AST Wong Cancer research 66 (22), 10902-10910, 2006 | 118 | 2006 |
| Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells LWT Cheung, SCL Au, ANY Cheung, HYS Ngan, J Tombran-Tink, ... Endocrinology 147 (9), 4179-4191, 2006 | 111 | 2006 |
| Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors LWT Cheung, S Yu, D Zhang, J Li, PKS Ng, N Panupinthu, S Mitra, Z Ju, ... Cancer Cell 26 (4), 479-494, 2014 | 97 | 2014 |
| Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer LWT Cheung, PCK Leung, AST Wong Oncogene 29 (16), 2427-2440, 2010 | 95 | 2010 |
| Regulation of the PI3K pathway through a p85α monomer–homodimer equilibrium LWT Cheung, KW Walkiewicz, TMD Besong, H Guo, DH Hawke, ST Arold, ... Elife 4, e06866, 2015 | 93 | 2015 |
| Ginsenoside-Rg1 induces angiogenesis via non-genomic crosstalk of glucocorticoid receptor and fibroblast growth factor receptor-1 LWT Cheung, KW Leung, CKC Wong, RNS Wong, AST Wong Cardiovascular research 89 (2), 419-425, 2011 | 75 | 2011 |
| Somatic mutations of PIK3R1 promote gliomagenesis SN Quayle, JY Lee, LWT Cheung, L Ding, R Wiedemeyer, RW Dewan, ... PloS one 7 (11), e49466, 2012 | 72 | 2012 |
| Exposure to light at night (LAN) and risk of breast cancer: A systematic review and meta-analysis KY Lai, C Sarkar, MY Ni, LWT Cheung, J Gallacher, C Webster Science of the Total Environment 762, 143159, 2021 | 64 | 2021 |
| Targeting therapeutic liabilities engendered by PIK3R1 mutations for cancer treatment LWT Cheung, GB Mills Pharmacogenomics 17 (3), 297-307, 2016 | 57 | 2016 |
| Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer X Li, VCY Mak, Y Zhou, C Wang, ESY Wong, R Sharma, Y Lu, ... Nature communications 10 (1), 716, 2019 | 50 | 2019 |
| Drugging IGF-1R in cancer: New insights and emerging opportunities P Wang, VCY Mak, LWT Cheung Genes & Diseases 10 (1), 199-211, 2023 | 48 | 2023 |
| A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets P Zhou, BKC Chan, YK Wan, CTL Yuen, GCG Choi, X Li, CSW Tong, ... Cell Reports 32 (6), 108020, 2020 | 46 | 2020 |
| P-cadherin cooperates with insulin-like growth factor-1 receptor to promote metastatic signaling of gonadotropin-releasing hormone in ovarian cancer via p120 catenin LWT Cheung, ASC Mak, ANY Cheung, HYS Ngan, PCK Leung, ... Oncogene 30 (26), 2964-2974, 2011 | 43 | 2011 |