Differential mass spectrometry: A label-free LC− MS method for finding significant differences in complex peptide and protein mixtures MC Wiener, JR Sachs, EG Deyanova, NA Yates Analytical chemistry 76 (20), 6085-6096, 2004 | 363 | 2004 |
Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations J Zhu, MC Wiener, C Zhang, A Fridman, E Minch, PY Lum, JR Sachs, ... PLoS computational biology 3 (4), e69, 2007 | 262 | 2007 |
Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-γ agonists DL Gerhold, F Liu, G Jiang, Z Li, J Xu, M Lu, JR Sachs, A Bagchi, ... Endocrinology 143 (6), 2106-2118, 2002 | 240 | 2002 |
Mass spectrometry data analysis techniques JR Sachs, MC Wiener, NA Yates US Patent 6,906,320, 2005 | 203 | 2005 |
Optimal dosing for targeted therapies in oncology: drug development cases leading by example JR Sachs, K Mayawala, S Gadamsetty, SP Kang, DP de Alwis Clinical Cancer Research 22 (6), 1318-1324, 2016 | 151 | 2016 |
A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults AO Aliprantis, CA Shaw, P Griffin, N Farinola, RA Railkar, X Cao, W Liu, ... Human Vaccines & Immunotherapeutics 17 (5), 1248-1261, 2021 | 133 | 2021 |
Using model‐based “learn and confirm” to reveal the pharmacokinetics‐pharmacodynamics relationship of pembrolizumab in the KEYNOTE‐001 Trial J Elassaiss‐Schaap, S Rossenu, A Lindauer, SP Kang, R De Greef, ... CPT: pharmacometrics & systems pharmacology 6 (1), 21-28, 2017 | 112 | 2017 |
Quantitative analysis of complex peptide mixtures using FTMS and differential mass spectrometry F Meng, MC Wiener, JR Sachs, C Burns, P Verma, CP Paweletz, ... Journal of the American Society for Mass Spectrometry 18 (2), 226-233, 2007 | 89 | 2007 |
High resolution discovery proteomics reveals candidate disease progression markers of Alzheimer’s disease in human cerebrospinal fluid RC Hendrickson, AYH Lee, Q Song, A Liaw, M Wiener, CP Paweletz, ... PloS one 10 (8), e0135365, 2015 | 79 | 2015 |
Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates T Zohar, JC Hsiao, N Mehta, J Das, A Devadhasan, W Karpinski, ... Cell host & microbe 30 (1), 41-52. e5, 2022 | 69 | 2022 |
Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometry CP Paweletz, MC Wiener, AY Bondarenko, NA Yates, Q Song, A Liaw, ... Journal of proteome research 9 (3), 1392-1401, 2010 | 51 | 2010 |
Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis BM Maas, J Lommerse, N Plock, RA Railkar, SYA Cheung, L Caro, ... EBioMedicine 73, 2021 | 40 | 2021 |
Electromechanical spectroscopy of cartilage using a surface probe with applied mechanical displacement JR Sachs, AJ Grodzinsky Journal of biomechanics 28 (8), 963-976, 1995 | 40 | 1995 |
An electromechanically coupled poroelastic médium driven by an applied electric-current-surface détection of bulk material properties JR Sachs, AJ Grodzinsky Physicochemical Hydrodynamics 11 (4), 585-614, 1989 | 38 | 1989 |
Sitagliptin 100 mg daily effect on DPP-4 inhibition and compound-specific glycemic improvement M Alba, D Sheng, Y Guan, D Williams-Herman, P Larson, JR Sachs, ... Current medical research and opinion 25 (10), 2507-2514, 2009 | 31 | 2009 |
Quantification and identification of components in solution mixtures from 1D proton NMR spectra using singular value decomposition Q Xu, JR Sachs, TC Wang, WH Schaefer Analytical chemistry 78 (20), 7175-7185, 2006 | 28 | 2006 |
Identification of peptidase substrates in human plasma by FTMS based differential mass spectrometry NA Yates, EG Deyanova, W Geissler, MC Wiener, JR Sachs, KK Wong, ... International Journal of Mass Spectrometry 259 (1-3), 174-183, 2007 | 25 | 2007 |
Immunogenicity and safety of a tetravalent recombinant subunit dengue vaccine in adults previously vaccinated with a live attenuated tetravalent dengue vaccine: results of a … AP Durbin, KK Pierce, BD Kirkpatrick, P Grier, BP Sabundayo, H He, ... The American journal of tropical medicine and hygiene 103 (2), 855, 2020 | 24 | 2020 |
Weakly nonlinear deformation of a thin poroelastic layer with a free surface OE Jensen, MR Glucksberg, JR Sachs, JB Grotberg | 24 | 1994 |
Safety and immunogenicity of the measles vector-based SARS-CoV-2 vaccine candidate, V591, in adults: results from a phase 1/2 randomised, double-blind, placebo-controlled, dose … F Vanhoutte, W Liu, RT Wiedmann, L Haspeslagh, X Cao, K Boundy, ... EBioMedicine 75, 2022 | 23 | 2022 |