Takip et
Nicolas Doucet
Nicolas Doucet
Centre Armand-Frappier Santé Biotechnologie, INRS, Université du Québec
inrs.ca üzerinde doğrulanmış e-posta adresine sahip - Ana Sayfa
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design
RA Chica, N Doucet, JN Pelletier
Current opinion in biotechnology 16 (4), 378-384, 2005
7612005
The end of an old hypothesis: the Pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids
CE Dulcey, V Dekimpe, DA Fauvelle, S Milot, MC Groleau, N Doucet, ...
Chemistry & biology 20 (12), 1481-1491, 2013
1622013
The flexibility of a distant loop modulates active site motion and product release in ribonuclease A
N Doucet, ED Watt, JP Loria
Biochemistry 48 (30), 7160-7168, 2009
982009
Incorporation of manganese complexes into xylanase: new artificial metalloenzymes for enantioselective epoxidation
M Allard, C Dupont, V Munoz Robles, N Doucet, A Lledós, JD Maréchal, ...
ChemBioChem 13 (2), 240-251, 2012
932012
Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 β-lactamase
N Doucet, PY De Wals, JN Pelletier
Journal of Biological Chemistry 279 (44), 46295-46303, 2004
752004
Combining chitinase C and N-acetylhexosaminidase from Streptomyces coelicolor A3 (2) provides an efficient way to synthesize N-acetylglucosamine from crystalline chitin
N Nguyen-Thi, N Doucet
Journal of Biotechnology 220, 25-32, 2016
732016
Short-chain flavor ester synthesis in organic media by an E. coli whole-cell biocatalyst expressing a newly characterized heterologous lipase
G Brault, F Shareck, Y Hurtubise, F Lépine, N Doucet
PLoS One 9 (3), e91872, 2014
712014
Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells
AA Grosset, M Labrie, D Gagné, MC Vladoiu, L Gaboury, N Doucet, ...
BMC cancer 14, 1-10, 2014
582014
NMR investigation of Tyr105 mutants in TEM-1 β-lactamase: dynamics are correlated with function
N Doucet, PY Savard, JN Pelletier
Journal of Biological Chemistry 282 (29), 21448-21459, 2007
552007
Isolation and Characterization of EstC, a New Cold-Active Esterase from Streptomyces coelicolor A3(2)
G Brault, F Shareck, Y Hurtubise, F Lépine, N Doucet
PloS one 7 (3), e32041, 2012
502012
Enzyme dynamics: Looking beyond a single structure
PK Agarwal, DN Bernard, K Bafna, N Doucet
ChemCatChem 12 (19), 4704-4720, 2020
482020
Structural and functional importance of local and global conformational fluctuations in the RN ase A superfamily
D Gagné, N Doucet
The FEBS journal 280 (22), 5596-5607, 2013
472013
Conservation of dynamics associated with biological function in an enzyme superfamily
C Narayanan, DN Bernard, K Bafna, D Gagné, CS Chennubhotla, ...
Structure 26 (3), 426-436. e3, 2018
462018
Conservation of flexible residue clusters among structural and functional enzyme homologues
D Gagné, LA Charest, S Morin, EL Kovrigin, N Doucet
Journal Of Biological Chemistry 287 (53), 44289-44300, 2012
462012
Protein context shapes the specificity of SH3 domain-mediated interactions in vivo
U Dionne, É Bourgault, AK Dubé, D Bradley, FJM Chartier, R Dandage, ...
Nature communications 12 (1), 1597, 2021
442021
Perturbation of the conformational dynamics of an active-site loop alters enzyme activity
D Gagné, RL French, C Narayanan, M Simonović, PK Agarwal, N Doucet
Structure 23 (12), 2256-2266, 2015
432015
Synthesis and biological assessment of a ruthenium (II) cyclopentadienyl complex in breast cancer cells and on the development of zebrafish embryos
G Golbaghi, I Pitard, M Lucas, MM Haghdoost, YL de Los Santos, ...
European journal of medicinal chemistry 188, 112030, 2020
422020
Direct phosphorylation of SRC homology 3 domains by tyrosine kinase receptors disassembles ligand-induced signaling networks
U Dionne, FJM Chartier, YL de Los Santos, N Lavoie, DN Bernard, ...
Molecular cell 70 (6), 995-1007. e11, 2018
422018
Alteration of hydrogen bonding in the vicinity of histidine 48 disrupts millisecond motions in RNase A
N Doucet, G Khirich, EL Kovrigin, JP Loria
Biochemistry 50 (10), 1723-1730, 2011
402011
Applications of NMR and computational methodologies to study protein dynamics
C Narayanan, K Bafna, LD Roux, PK Agarwal, N Doucet
Archives of biochemistry and biophysics 628, 71-80, 2017
392017
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Makaleler 1–20