| The role of human carboxylesterases in drug metabolism: have we overlooked their importance? S Casey Laizure, V Herring, Z Hu, K Witbrodt, RB Parker Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 33 (2 …, 2013 | 479 | 2013 |
| Dose-dependent association between UGT1A1* 28 genotype and irinotecan-induced neutropenia: low doses also increase risk ZY Hu, Q Yu, Q Pei, C Guo Clinical Cancer Research 16 (15), 3832-3842, 2010 | 165 | 2010 |
| Dose-dependent association between UGT1A1∗ 28 polymorphism and irinotecan-induced diarrhoea: a meta-analysis ZY Hu, Q Yu, YS Zhao European journal of cancer 46 (10), 1856-1865, 2010 | 126 | 2010 |
| Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis SC Laizure, RB Parker, VL Herring, ZY Hu Drug Metabolism and Disposition 42 (2), 201-206, 2014 | 121 | 2014 |
| A phase I/Ib trial of the VEGFR-sparing multikinase RET inhibitor RXDX-105 A Drilon, S Fu, MR Patel, M Fakih, D Wang, AJ Olszanski, D Morgensztern, ... Cancer discovery 9 (3), 384-395, 2019 | 112 | 2019 |
| Combinatorial metabolism notably affects human systemic exposure to ginsenosides from orally administered extract of Panax notoginseng roots (Sanqi) Z Hu, J Yang, C Cheng, Y Huang, F Du, F Wang, W Niu, F Xu, R Jiang, ... Drug Metabolism and Disposition 41 (7), 1457-1469, 2013 | 77 | 2013 |
| Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in … ZY Hu, RB Parker, VL Herring, SC Laizure Analytical and bioanalytical chemistry 405, 1695-1704, 2013 | 55 | 2013 |
| Sex-dependent differences in cytochrome P450 3A activity as assessed by midazolam disposition in humans: a meta-analysis ZY Hu, YS Zhao Drug metabolism and disposition 38 (5), 817-823, 2010 | 55 | 2010 |
| Effects of alcohol on human carboxylesterase drug metabolism RB Parker, ZY Hu, B Meibohm, SC Laizure Clinical pharmacokinetics 54, 627-638, 2015 | 48 | 2015 |
| Oral bioavailability and brain penetration of (−)‐stepholidine, a tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors, in rats Y Sun, J Dai, Z Hu, F Du, W Niu, F Wang, F Liu, G Jin, C Li British journal of pharmacology 158 (5), 1302-1312, 2009 | 41 | 2009 |
| Physiologically based pharmacokinetic modelling and in vivo [I]/Ki accurately predict P‐glycoprotein‐mediated drug‐drug interactions with dabigatran etexilate Y Zhao, ZY Hu British journal of pharmacology 171 (4), 1043-1053, 2014 | 40 | 2014 |
| Simultaneous determination of 6β-hydroxycortisol and cortisol in human urine and plasma by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A … Z Hu, Q Gong, X Hu, L Wang, Y Cao, W Cao, Q Yu, Z Cheng Journal of Chromatography B 826 (1-2), 238-243, 2005 | 39 | 2005 |
| Measurement of caffeine and its three primary metabolites in human plasma by HPLC‐ESI‐MS/MS and clinical application F Chen, ZY Hu, RB Parker, SC Laizure Biomedical Chromatography 31 (6), e3900, 2017 | 37 | 2017 |
| CYP3A4-mediated pharmacokinetic interactions in cancer therapy D Tian, Z Hu Current Drug Metabolism 15 (8), 808-817, 2014 | 37 | 2014 |
| Evaluation of Chlorpheniramine Maleate microparticles in orally disintegrating film and orally disintegrating tablet for pediatrics H Lou, M Liu, W Qu, Z Hu, E Brunson, J Johnson, H Almoazen Drug Development and Industrial Pharmacy 40 (7), 910-918, 2014 | 36 | 2014 |
| HPLC–MS–MS for the simultaneous determination of atorvastatin and amlodipine in plasma of hypertensive patients Q Yu, ZY Hu, FY Zhu, JH Zhu, LL Wan, Y Li, C Guo Chromatographia 73, 257-262, 2011 | 34 | 2011 |
| A physiologically based pharmacokinetic model of alvespimycin in mice and extrapolation to rats and humans ZY Hu, J Lu, Y Zhao British journal of pharmacology 171 (11), 2778-2789, 2014 | 31 | 2014 |
| Association between Common CYP1A2 Polymorphisms and Theophylline Metabolism in Non‐smoking Healthy Volunteers L Wang, Z Hu, X Deng, Y Wang, Z Zhang, ZN Cheng Basic & clinical pharmacology & toxicology 112 (4), 257-263, 2013 | 30 | 2013 |
| Pharmacokinetics of imipenem/cilastatin burn intensive care unit patients undergoing high‐dose continuous venovenous hemofiltration BA Boucher, JQ Hudson, DM Hill, JM Swanson, GC Wood, SC Laizure, ... Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 36 (12 …, 2016 | 27 | 2016 |
| Evaluation of CYP3A activity in humans using three different parameters based on endogenous cortisol metabolism X Luo, X Li, Z Hu, Z Cheng Acta Pharmacologica Sinica 30 (9), 1323-1329, 2009 | 27 | 2009 |
