Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation F Fallarino, C Volpi, F Fazio, S Notartomaso, C Vacca, C Busceti, ... Nature medicine 16 (8), 897-902, 2010 | 184 | 2010 |
Xanthurenic acid activates mGlu2/3 metabotropic glutamate receptors and is a potential trait marker for schizophrenia F Fazio, L Lionetto, M Curto, L Iacovelli, M Cavallari, C Zappulla, ... Scientific reports 5 (1), 17799, 2015 | 116 | 2015 |
Altered kynurenine pathway metabolites in serum of chronic migraine patients M Curto, L Lionetto, A Negro, M Capi, F Fazio, MA Giamberardino, ... The journal of headache and pain 17, 1-7, 2016 | 98 | 2016 |
Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study. L Lionetto, M Ulivieri, M Capi, D De Bernardini, F Fazio, A Petrucca, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (3), 166042, 2021 | 94 | 2021 |
Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors F Fazio, L Lionetto, G Molinaro, HO Bertrand, F Acher, RT Ngomba, ... Molecular pharmacology 81 (5), 643-656, 2012 | 94 | 2012 |
Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors F Fazio, L Lionetto, M Curto, L Iacovelli, CS Copeland, SA Neale, V Bruno, ... Neuropharmacology 112, 365-372, 2017 | 85 | 2017 |
Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1 S Notartomaso, C Zappulla, F Biagioni, M Cannella, D Bucci, G Mascio, ... Molecular brain 6, 1-17, 2013 | 74 | 2013 |
Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice F Fazio, C Zappulla, S Notartomaso, C Busceti, A Bessede, P Scarselli, ... Neuropharmacology 81, 237-243, 2014 | 62 | 2014 |
N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors M Bernabucci, S Notartomaso, C Zappulla, F Fazio, M Cannella, ... Molecular pain 8, 1744-8069-8-77, 2012 | 61 | 2012 |
Targeting metabotropic glutamate receptors for the treatment of neuroinflammation F Fazio, M Ulivieri, C Volpi, M Gargaro, F Fallarino Current Opinion in Pharmacology 38, 16-23, 2018 | 48 | 2018 |
Switch in the expression of mGlu1 and mGlu5 metabotropic glutamate receptors in the cerebellum of mice developing experimental autoimmune encephalomyelitis and in autoptic … F Fazio | 47 | 2008 |
Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia F Nicoletti, R Orlando, L Di Menna, M Cannella, S Notartomaso, G Mascio, ... Frontiers in psychiatry 10, 49, 2019 | 46 | 2019 |
Vasorelaxing action of the kynurenine metabolite, xanthurenic acid: the missing link in endotoxin-induced hypotension? F Fazio, A Carrizzo, L Lionetto, A Damato, L Capocci, M Ambrosio, ... Frontiers in pharmacology 8, 214, 2017 | 43 | 2017 |
The trace kynurenine, cinnabarinic acid, displays potent antipsychotic-like activity in mice and its levels are reduced in the prefrontal cortex of individuals affected by … M Ulivieri, JM Wierońska, L Lionetto, K Martinello, P Cieslik, A Chocyk, ... Schizophrenia Bulletin 46 (6), 1471-1481, 2020 | 28 | 2020 |
Fathoming the kynurenine pathway in migraine: why understanding the enzymatic cascades is still critically important M Curto, L Lionetto, F Fazio, DD Mitsikostas, P Martelletti Internal and emergency medicine 10, 413-421, 2015 | 28 | 2015 |
Improving adherence to pharmacological treatment for schizophrenia: a systematic assessment M Curto, F Fazio, M Ulivieri, S Navari, L Lionetto, RJ Baldessarini Expert opinion on pharmacotherapy 22 (9), 1143-1155, 2021 | 27 | 2021 |
mGlu3 receptor regulates microglial cell reactivity in neonatal rats M Zinni, J Mairesse, J Pansiot, F Fazio, L Iacovelli, N Antenucci, ... Journal of Neuroinflammation 18, 1-16, 2021 | 20 | 2021 |
Hippocampal transcriptome deconvolution reveals differences in cell architecture of not demented elderly subjects underwent late-life physical activity C Sanfilippo, G Musumeci, P Castrogiovanni, F Fazio, GL Volti, ... Journal of Chemical Neuroanatomy 113, 101934, 2021 | 11 | 2021 |
Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease … C Sanfilippo, L Giuliano, P Castrogiovanni, R Imbesi, M Ulivieri, F Fazio, ... Current Neuropharmacology 21 (3), 740-760, 2023 | 9 | 2023 |
Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis M Curto, L Lionetto, F Fazio, V Corigliano, A Comparelli, S Ferracuti, ... Schizophrenia research 208, 465-466, 2019 | 9 | 2019 |