Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets Y Schaerli, RC Wootton, T Robinson, V Stein, C Dunsby, MAA Neil, ... Analytical chemistry 81 (1), 302-306, 2009 | 373 | 2009 |
Synthetic protein switches: design principles and applications V Stein, K Alexandrov Trends in biotechnology 33 (2), 101-110, 2015 | 179 | 2015 |
New genotype–phenotype linkages for directed evolution of functional proteins H Leemhuis, V Stein, AD Griffiths, F Hollfelder Current Opinion in Structural Biology 15 (4), 472-478, 2005 | 167 | 2005 |
Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases AP Siskos, A Baerga-Ortiz, S Bali, V Stein, H Mamdani, D Spiteller, ... Chemistry & biology 12 (10), 1145-1153, 2005 | 148 | 2005 |
Reaction site mapping of xenobiotic biotransformations S Boyer, CH Arnby, L Carlsson, J Smith, V Stein, RC Glen Journal of chemical information and modeling 47 (2), 583-590, 2007 | 125 | 2007 |
Protease-based synthetic sensing and signal amplification V Stein, K Alexandrov Proceedings of the National Academy of Sciences 111 (45), 15934-15939, 2014 | 102 | 2014 |
Engineered PQQ-glucose dehydrogenase as a universal biosensor platform Z Guo, L Murphy, V Stein, WA Johnston, S Alcala-Perez, K Alexandrov Journal of the American Chemical Society 138 (32), 10108-10111, 2016 | 71 | 2016 |
Engineering PQQ-glucose dehydrogenase into an allosteric electrochemical Ca2+ sensor Z Guo, WA Johnston, V Stein, P Kalimuthu, S Perez-Alcala, PV Bernhardt, ... Chemical Communications 52 (3), 485-488, 2015 | 52 | 2015 |
A covalent chemical genotype–phenotype linkage for in vitro protein evolution V Stein, I Sielaff, K Johnsson, F Hollfelder Chembiochem 8 (18), 2191-2194, 2007 | 52 | 2007 |
USER friendly DNA recombination (USERec): a simple and flexible near homology-independent method for gene library construction BRM Villiers, V Stein, F Hollfelder Protein Engineering, Design & Selection 23 (1), 1-8, 2010 | 50 | 2010 |
Linker engineering in the context of synthetic protein switches and sensors A Gräwe, V Stein Trends in biotechnology 39 (7), 731-744, 2021 | 46 | 2021 |
Semisynthetic tRNA Complement Mediates in Vitro Protein Synthesis Z Cui, V Stein, Z Tnimov, S Mureev, K Alexandrov Journal of the American Chemical Society 137 (13), 4404-4413, 2015 | 46 | 2015 |
iFLinkC: an iterative functional linker cloning strategy for the combinatorial assembly and recombination of linker peptides with functional domains A Gräwe, J Ranglack, A Weyrich, V Stein Nucleic acids research 48 (4), e24-e24, 2020 | 44 | 2020 |
SPORCalc: A development of a database analysis that provides putative metabolic enzyme reactions for ligand-based drug design J Smith, V Stein Computational Biology and Chemistry 33 (2), 149-159, 2009 | 35 | 2009 |
SNAP dendrimers: Multivalent protein display on dendrimer‐like DNA for directed evolution M Kaltenbach, V Stein, F Hollfelder Chembiochem 12 (14), 2208-2216, 2011 | 34 | 2011 |
Isothermal DNA amplification using the T4 replisome: circular nicking endonuclease-dependent amplification and primase-based whole-genome amplification Y Schaerli, V Stein, MM Spiering, SJ Benkovic, C Abell, F Hollfelder Nucleic acids research 38 (22), e201-e201, 2010 | 34 | 2010 |
Ultrasensitive scaffold-dependent protease sensors with large dynamic range V Stein, M Nabi, K Alexandrov ACS Synthetic Biology 6 (7), 1337-1342, 2017 | 32 | 2017 |
Towards the Systematic Mapping and Engineering of the Protein Prenylation Machinery in Saccharomyces cerevisiae V Stein, MH Kubala, J Steen, SM Grimmond, K Alexandrov PloS one 10 (3), e0120716, 2015 | 27 | 2015 |
An efficient method to assemble linear DNA templates for in vitro screening and selection systems V Stein, F Hollfelder Nucleic acids research 37 (18), e122-e122, 2009 | 26 | 2009 |
Ultrasensitive and selective copper (ii) detection: Introducing a bioinspired and robust sensor LK Müller, I Duznovic, D Tietze, W Weber, M Ali, V Stein, W Ensinger, ... Chemistry–A European Journal 26 (39), 8511-8517, 2020 | 25 | 2020 |