Reductive carboxylation supports growth in tumour cells with defective mitochondria AR Mullen, WW Wheaton, ES Jin, PH Chen, LB Sullivan, T Cheng, ... Nature 481 (7381), 385-388, 2012 | 1463 | 2012 |
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells T Cheng, J Sudderth, C Yang, AR Mullen, ES Jin, JM Matés, ... Proceedings of the National Academy of Sciences 108 (21), 8674-8679, 2011 | 552 | 2011 |
Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects AR Mullen, Z Hu, X Shi, L Jiang, LK Boroughs, Z Kovacs, R Boriack, ... Cell reports 7 (5), 1679-1690, 2014 | 384 | 2014 |
The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling LB Sullivan, E Martinez-Garcia, H Nguyen, AR Mullen, E Dufour, ... Molecular cell 51 (2), 236-248, 2013 | 330 | 2013 |
Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development RB Hamanaka, A Glasauer, P Hoover, S Yang, H Blatt, AR Mullen, ... Science signaling 6 (261), ra8-ra8, 2013 | 319 | 2013 |
Glutamine: pleiotropic roles in tumor growth and stress resistance NP Shanware, AR Mullen, RJ DeBerardinis, RT Abraham Journal of molecular medicine 89, 229-236, 2011 | 230 | 2011 |
Genetically-defined metabolic reprogramming in cancer AR Mullen, RJ DeBerardinis Trends in Endocrinology & Metabolism 23 (11), 552-559, 2012 | 100 | 2012 |
SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair KM Providence, SP Higgins, A Mullen, A Battista, R Samarakoon, ... Archives of Dermatological Research 300, 303-310, 2008 | 82 | 2008 |
Metabolic changes in cancer cells upon suppression of MYC E Anso, AR Mullen, DW Felsher, JM Matés, RJ DeBerardinis, NS Chandel Cancer & metabolism 1, 1-10, 2013 | 77 | 2013 |
Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction N Cetinbas, M Daugaard, AR Mullen, S Hajee, B Rotblat, A Lopez, A Li, ... Oncogene 34 (30), 4005-4010, 2015 | 35 | 2015 |
N-acetyl cysteine abrogates silver-induced reactive oxygen species in human cells without altering silver-based antimicrobial activity KN Shah, PN Shah, AR Mullen, Q Chen, MR Southerland, B Chirra, ... Toxicology letters 332, 118-129, 2020 | 10 | 2020 |
Reductive Carboxylation Is a Novel Pathway of Glutamine Metabolism That Supports the Growth of Tumor Cells with Metabolic Defects AR Mullen | 1 | 2013 |
Friday 24 July 2015 P Higgins, N Latta, A Seeley, S Hettige, K Barnett, S Nicholls, K Clarke, ... Journal of Medical Radiation Sciences 62 (Suppl 1), 1-36, 2015 | | 2015 |
Amelioration Of Cytotoxic And Metabolic Effects Of Silver Cations On Respiratory Epithelial Cells By N-Acetyl Cysteine PN Shah, AR Mullen, RJ DeBerardinis, CL Cannon B52. TOXICOLOGY OF OCCUPATIONAL AND ENVIRONMENTAL DISEASE, A3260-A3260, 2011 | | 2011 |
Exome sequencing and ex-vivo metabolic flux analysis as a diagnostic platform for inborn errors of metabolism AR Mullen, F Jiang, R Haller, J Cohen, RJ DeBerardinis MOLECULAR GENETICS AND METABOLISM 102 (3), 249-250, 2011 | | 2011 |
545 The consequences of enhanced cell-autonomous glucose metabolism AR Mullen, RJ DeBerardinis, W Luo, GL Semenza, I Goldstein, V Rotter, ... | | |