Tight junction pore and leak pathways: a dynamic duo L Shen, CR Weber, DR Raleigh, D Yu, JR Turner Annual review of physiology 73 (1), 283-309, 2011 | 985 | 2011 |
A porous defense: the leaky epithelial barrier in intestinal disease DR Clayburgh, L Shen, JR Turner Laboratory investigation 84 (3), 282-291, 2004 | 633 | 2004 |
Molecular ordering of the initial signaling events of CD95 A Algeciras-Schimnich, L Shen, BC Barnhart, AE Murmann, JK Burkhardt, ... Molecular and cellular biology 22 (1), 207-220, 2002 | 554 | 2002 |
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure L Shen, ED Black, ED Witkowski, WI Lencer, V Guerriero, ... Journal of cell science 119 (10), 2095-2106, 2006 | 551 | 2006 |
Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection S Liu, W Yang, L Shen, JR Turner, CB Coyne, T Wang Journal of virology 83 (4), 2011-2014, 2009 | 501 | 2009 |
Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo AM Marchiando, L Shen, WV Graham, CR Weber, BT Schwarz, JR Austin, ... Journal of Cell Biology 189 (1), 111-126, 2010 | 498 | 2010 |
Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis L Su, L Shen, DR Clayburgh, SC Nalle, EA Sullivan, JB Meddings, ... Gastroenterology 136 (2), 551-563, 2009 | 495 | 2009 |
The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state L Shen, CR Weber, JR Turner The Journal of cell biology 181 (4), 683-695, 2008 | 417 | 2008 |
Recognition of host immune activation by Pseudomonas aeruginosa L Wu, O Estrada, O Zaborina, M Bains, L Shen, JE Kohler, N Patel, ... Science 309 (5735), 774-777, 2005 | 409 | 2005 |
TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis L Su, SC Nalle, L Shen, ES Turner, G Singh, LA Breskin, EA Khramtsova, ... Gastroenterology 145 (2), 407-415, 2013 | 406 | 2013 |
Tight junction–associated MARVEL proteins MarvelD3, tricellulin, and occludin have distinct but overlapping functions DR Raleigh, AM Marchiando, Y Zhang, L Shen, H Sasaki, Y Wang, ... Molecular biology of the cell 21 (7), 1200-1213, 2010 | 383 | 2010 |
Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis L Shen, JR Turner Molecular biology of the cell 16 (9), 3919-3936, 2005 | 366 | 2005 |
Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity CR Weber, DR Raleigh, L Su, L Shen, EA Sullivan, Y Wang, JR Turner Journal of Biological Chemistry 285 (16), 12037-12046, 2010 | 331 | 2010 |
The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding AM Marchiando, L Shen, WV Graham, KL Edelblum, CA Duckworth, ... Gastroenterology 140 (4), 1208-1218. e2, 2011 | 314 | 2011 |
Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5 CB Coyne, L Shen, JR Turner, JM Bergelson Cell host & microbe 2 (3), 181-192, 2007 | 306 | 2007 |
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function DR Raleigh, DM Boe, D Yu, CR Weber, AM Marchiando, EM Bradford, ... Journal of Cell Biology 193 (3), 565-582, 2011 | 285 | 2011 |
PKCη regulates occludin phosphorylation and epithelial tight junction integrity T Suzuki, BC Elias, A Seth, L Shen, JR Turner, F Giorgianni, D Desiderio, ... Proceedings of the National Academy of Sciences 106 (1), 61-66, 2009 | 275 | 2009 |
MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function D Yu, AM Marchiando, CR Weber, DR Raleigh, Y Wang, L Shen, ... Proceedings of the National Academy of Sciences 107 (18), 8237-8241, 2010 | 272 | 2010 |
Tight junctions on the move: molecular mechanisms for epithelial barrier regulation L Shen Annals of the New York Academy of Sciences 1258 (1), 9-18, 2012 | 254 | 2012 |
Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed L Shen, JR Turner American journal of physiology-gastrointestinal and liver physiology 290 (4 …, 2006 | 254 | 2006 |