Takip et
Le Shen
Le Shen
the University of Chicago
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Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Tight junction pore and leak pathways: a dynamic duo
L Shen, CR Weber, DR Raleigh, D Yu, JR Turner
Annual review of physiology 73 (1), 283-309, 2011
9852011
A porous defense: the leaky epithelial barrier in intestinal disease
DR Clayburgh, L Shen, JR Turner
Laboratory investigation 84 (3), 282-291, 2004
6332004
Molecular ordering of the initial signaling events of CD95
A Algeciras-Schimnich, L Shen, BC Barnhart, AE Murmann, JK Burkhardt, ...
Molecular and cellular biology 22 (1), 207-220, 2002
5542002
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
L Shen, ED Black, ED Witkowski, WI Lencer, V Guerriero, ...
Journal of cell science 119 (10), 2095-2106, 2006
5512006
Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection
S Liu, W Yang, L Shen, JR Turner, CB Coyne, T Wang
Journal of virology 83 (4), 2011-2014, 2009
5012009
Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
AM Marchiando, L Shen, WV Graham, CR Weber, BT Schwarz, JR Austin, ...
Journal of Cell Biology 189 (1), 111-126, 2010
4982010
Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
L Su, L Shen, DR Clayburgh, SC Nalle, EA Sullivan, JB Meddings, ...
Gastroenterology 136 (2), 551-563, 2009
4952009
The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state
L Shen, CR Weber, JR Turner
The Journal of cell biology 181 (4), 683-695, 2008
4172008
Recognition of host immune activation by Pseudomonas aeruginosa
L Wu, O Estrada, O Zaborina, M Bains, L Shen, JE Kohler, N Patel, ...
Science 309 (5735), 774-777, 2005
4092005
TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis
L Su, SC Nalle, L Shen, ES Turner, G Singh, LA Breskin, EA Khramtsova, ...
Gastroenterology 145 (2), 407-415, 2013
4062013
Tight junction–associated MARVEL proteins MarvelD3, tricellulin, and occludin have distinct but overlapping functions
DR Raleigh, AM Marchiando, Y Zhang, L Shen, H Sasaki, Y Wang, ...
Molecular biology of the cell 21 (7), 1200-1213, 2010
3832010
Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis
L Shen, JR Turner
Molecular biology of the cell 16 (9), 3919-3936, 2005
3662005
Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity
CR Weber, DR Raleigh, L Su, L Shen, EA Sullivan, Y Wang, JR Turner
Journal of Biological Chemistry 285 (16), 12037-12046, 2010
3312010
The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding
AM Marchiando, L Shen, WV Graham, KL Edelblum, CA Duckworth, ...
Gastroenterology 140 (4), 1208-1218. e2, 2011
3142011
Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5
CB Coyne, L Shen, JR Turner, JM Bergelson
Cell host & microbe 2 (3), 181-192, 2007
3062007
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function
DR Raleigh, DM Boe, D Yu, CR Weber, AM Marchiando, EM Bradford, ...
Journal of Cell Biology 193 (3), 565-582, 2011
2852011
PKCη regulates occludin phosphorylation and epithelial tight junction integrity
T Suzuki, BC Elias, A Seth, L Shen, JR Turner, F Giorgianni, D Desiderio, ...
Proceedings of the National Academy of Sciences 106 (1), 61-66, 2009
2752009
MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function
D Yu, AM Marchiando, CR Weber, DR Raleigh, Y Wang, L Shen, ...
Proceedings of the National Academy of Sciences 107 (18), 8237-8241, 2010
2722010
Tight junctions on the move: molecular mechanisms for epithelial barrier regulation
L Shen
Annals of the New York Academy of Sciences 1258 (1), 9-18, 2012
2542012
Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed
L Shen, JR Turner
American journal of physiology-gastrointestinal and liver physiology 290 (4 …, 2006
2542006
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