| Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21 T Inagaki, P Dutchak, G Zhao, X Ding, L Gautron, V Parameswara, Y Li, ... Cell metabolism 5 (6), 415-425, 2007 | 1773 | 2007 |
| Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones PA Dutchak, T Katafuchi, AL Bookout, JH Choi, TY Ruth, DJ Mangelsdorf, ... Cell 148 (3), 556-567, 2012 | 635 | 2012 |
| Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ W Wei, PA Dutchak, X Wang, X Ding, X Wang, AL Bookout, R Goetz, ... Proceedings of the National Academy of Sciences 109 (8), 3143-3148, 2012 | 434 | 2012 |
| Metabolic Networks Influencing Skeletal Muscle Fiber Composition I Bourdeau-Julien, CF Sephton, PA Dutchak Frontiers in Cell and Developmental Biology 6, 125, 2018 | 79 | 2018 |
| Loss of a negative regulator of mTORC1 induces aerobic glycolysis and altered fiber composition in skeletal muscle PA Dutchak, SJ Estill-Terpack, AA Plec, X Zhao, C Yang, J Chen, B Ko, ... Cell reports 23 (7), 1907-1914, 2018 | 60 | 2018 |
| Regulation of hematopoiesis and methionine homeostasis by mTORC1 inhibitor NPRL2 PA Dutchak, S Laxman, SJ Estill, C Wang, Y Wang, Y Wang, GB Bulut, ... Cell reports 12 (3), 371-379, 2015 | 52 | 2015 |
| FUS contributes to mTOR-dependent inhibition of translation M Sévigny, IB Julien, JP Venkatasubramani, JB Hui, PA Dutchak, ... Journal of Biological Chemistry 295 (52), 18459-18473, 2020 | 47 | 2020 |
| Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease PA Gelon, PA Dutchak, CF Sephton Frontiers in Molecular Neuroscience, 510, 2022 | 42 | 2022 |
| NPRL2 inhibition of mTORC1 controls sodium channel expression and brain amino acid homeostasis JB Hui, JCH Silva, MC Pelaez, M Sévigny, JP Venkatasubramani, ... Eneuro 9 (2), 2022 | 8 | 2022 |
| Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition CFS Mari Carmen Pelaez, Antoine Desmeules, Pauline A. Gelon, Bastien Glasson ... Acta Neuropathologica Communications 11, 1-21, 2023 | 7* | 2023 |
| A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics G Nicolas, M Sévigny, F Lecoquierre, F Marguet, A Deschênes, ... Acta neuropathologica communications 10 (1), 20, 2022 | 7 | 2022 |
| Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation G Aggarwal, S Banerjee, SA Jones, Y Benchaar, J Bélanger, M Sévigny, ... Journal of Biological Chemistry 299 (12), 2023 | 5 | 2023 |
| GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1 M Muller, J Bélanger, I Hadj-Aissa, C Zhang, CF Sephton, PA Dutchak Int. J. Mol. Sci. 25 (4), doi.org/10.3390/ijms25042068, 2024 | 3 | 2024 |
| Antisense oligonucleotides targeting miR‐29b binding site increase translation of progranulin protein: potential therapeutic strategy for progranulin‐deficient frontotemporal … G Aggarwal, S Banerjee, SA Jones, M Pavlack, Y Benchaar, J Bélanger, ... Alzheimer's & Dementia 18, e067828, 2022 | | 2022 |
| Altering cellular differentiation and energy metabolism by the mTORC1 inhibitor NPRL2 PA Dutchak, SJ Terpack, BP Tu Molecular Cancer Research 14 (4_Supplement), B08-B08, 2016 | | 2016 |
| Metabolic Regulation by Fibroblast Growth Factor 21 PA Dutchak | | 2011 |
